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Biomedical subjects

P Oja

Publications and source records attributed to P Oja.

102 records · Page 6Linked to original sources
PubMed1980

Mortality and incidence of chest pain after an exercise intervention programme.

One hundred and sixty-six middle-aged Finnish men free of clinical coronary heart disease (CHD), but having at least one CHD risk factor, participated in an 18-month controlled exercise intervention study, one-half as an exercising group and the other half as a matched control group; thereafter all 166 followed a partially controlled exercise programme for the next year. These men formed the intervention group for the present follow-up study covering the subsequent 6 years. The reference group for the follow-up comprised 152 men who fulfilled the same inclusion criteria for the original study as the intervention subjects, but who had been excluded from the study for non-medical reasons, mainly because they could not be pair-matched. Mortality statistics were collected, and a postal questionnaire on chest pain symptoms and physical activity was sent to all of the men 8 years after the start of the study. On CHD death and four deaths occurred in the reference group, and one CHD and no other deaths in the intervention group. Severe chest pain possibly suggestive of myocardial infarction was more common in the reference group than in the intervention group, but no difference was found in angina pectoris symptoms. The level of recent physical activity or smoking did not affect the chest pain symptoms independently.

Adult↗
PubMed1977

Age and sex as determinants of the relative aerobic strain of nonmotorized mail delivery.

The relative aerobic strain (RAS) of nonmotorized mail delivery was assessed in 54 Finnish mail carriers who represented both sexes, the entire workage range and both downtown and suburban delivery districts. The mean RAS of the entire delivery time was 55% of the maximal oxygen uptake (ml/kg-min). It was higher for women than for men, and higher for suburban than for downtown delivery. The RAS tended to increase systematically with age after the age of 50. The work strain of mail carriers of over 50 years of age, especially of older women carriers in suburban areas, was concluded to be high enough to lead to possible excessive strain on the workers.

Adult↗
PubMedDate not supplied

Circulating oxidized low-density lipoprotein and common carotid artery intima-media thickness in a random sample of middle-aged men.

Circulating oxidized low-density lipoprotein (oxLDL) has been suggested to play an important role in atherosclerosis development. According to previous observations, oxLDL correlates with clinically manifest coronary and carotid artery disease. We investigated the association between the oxLDL concentration measured directly in plasma and common carotid artery intima-media thickness (IMT) in a population-based, case-control study in middle-aged men from Southern Finland. oxLDL was determined in 214 men by a commercially available sandwich ELISA test (Mercodia). Carotid artery IMT was measured at 12 standardized segments by B-mode ultrasonography (at the near and far wall of the left and right common carotid arteries, bifurcations and internal carotid arteries), and the overall mean maximum IMT (MMaxIMT) was calculated. The MMaxIMT of the carotid arteries was significantly associated with circulating oxLDL (r(s) = 0.16, p = 0.018). In a stepwise multiple regression model with MMaxIMT as dependent variable and systolic blood pressure, smoking, oxLDL, HDL cholesterol and apolipoprotein B as covariates, systolic blood pressure (beta = 0.22, p < 0.001), oxLDL (beta = 0.15, p = 0.022) and smoking (beta = 0.17, p = 0.014) showed an independent association with IMT (R(2) = 0.10, p < 0.001). Our results show that oxLDL measured directly from plasma is independently associated with subclinical carotid artery atherosclerosis in middle-aged men.

Carotid Arteries↗
PubMedDate not supplied

The site-specific effects of long-term unilateral activity on bone mineral density and content.

This study assessed the site-specific effects of long-term tennis playing on the bone mineral density (BMD) and content (BMC) of upper extremities in male Finnish top-level players using a dual energy x-ray absorptiometric (DXA) scanner. In players (n = 20), the BMDs and BMCs were significantly higher in each bone of the playing right extremity (p < 0.05-0.001), the side-to-side difference being largest in the humeral shaft (BMD + 25.4%, BMC + 28.7%) and proximal humerus (BMD + 14.4%, BMC + 20.5%), and smallest in the ulnar shaft (BMD + 3.1%, BMC + 7.5%) and distal ulna (BMD + 6.3%, BMC + 7.8%). In sex-, age-, weight-, and height-matched controls (n = 20), the right-to-left differences were small ranging from 0.0% to + 6.4% (average +3%). The number of training sessions per week was the only variable in muscle strength and training history assessment which showed, in several anatomic sites, a significant correlation with the relative bone mineral variables (r = 0.460-0.627, p < 0.05-0.001). In conclusion, long-term unilateral tennis activity had a clearly positive effect on the BMD and BMC of the bones of the playing extremity. The effect was very site-specific, being greatest in the humerus and smallest in the ulna. The effect was always greater in BMC than BMD indicating that the excess mineral was used not only for condensation of the bone tissue, but also for enlargement of bone dimensions.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Bone mineral density and muscle strength of lower extremities after long-term strength training, subsequent knee ligament injury and rehabilitation: a unique 2-year follow-up of a 26-year-old female student.

Physical training is shown to have potential to increase the mass of healthy bones. In contrast, immobilization, used as a treatment of soft tissue and bone injuries, is shown to result in atrophy of these tissues. In this unique 26-month follow-up of a 26-year-old female student, we determined the effects of a 1-year strenuous unilateral lower limb strength training and subsequent anterior cruciate ligament (ACL) rupture on bone mineral density (BMD) of lumbar spine and lower extremities (femoral neck, distal femur, patella, proximal tibia, calcaneus), measured repeatedly (11 times) by dual-energy X-ray absorptiometry (DXA). Also, the strength and functional characteristics of the lower extremities were repeatedly examined. This prospective study strikingly demonstrated the deleterious effects of an ACL rupture on the BMD of the affected limb in contrast to beneficial but modest effects of the preceding controlled training. The site-specific increases in the BMD were 1.8-3.1% during the training. The posttraumatic decrease in the BMD of the injured knee was rapid and corresponded to approximately 2 SD (approximately 20%) observed in the age- and sex-matched population. A year after the injury, the subject's knee function and muscular performance as well as the usage of the injured limb were completely recovered, but the site-specific BMDs were still approximately 1 SD below the subject's baseline BMD, although continuously increasing. This study suggests that considerable posttraumatic osteopenia at the affected bone sites occurs quickly regardless of appropriate preventive and rehabilitative actions, and the time needed for steady-state and recovery will be long.(ABSTRACT TRUNCATED AT 250 WORDS)

Absorptiometry, Photon↗