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Biomedical subjects

P North

Publications and source records attributed to P North.

29 records · Page 2Linked to original sources

[Clinical and E.E.G. study of 9 cases of cortical blindness (author's transl)].

The authors report 9 cases of cortical blindness (7 of vascular origin, 2 due to septic embolism). These were characterised by blindness, loss of the blink reflex in response to threat, and of optokinetic nystagmus, conservation of the pupil reflexes, a confusional state with memory disturbances and anosognosia. The accompanying E.E.G. changes were basically impoverishment of occipital alpha activity, with theta and delta waves mainly in posterior regions on one or both sides; blocking to eye opening was absent, and following of the occiptal background rhythm in response to photic stimulation was rare and partial. One patient developed repetitive slow waves in the left occiptal region, another developed bi-occipital spikes and a third developed bi-occipital paroxymal activity, more predominant on the right. These abnormalities resemble those seen during extraterritorial circulatory insufficiency or air emboli.

Aged↗

An informal assessment of nutritional status in acute stroke for use in an international multicentre trial of feeding regimens.

Patients with acute stroke may become malnourished because of feeding difficulties, so dietary supplementation may improve outcome. We investigated the validity and reliability of an 'eyeball' assessment of nutritional status for use in an international trial of different feeding following acute stroke. One hundred and one inpatients (mean age 75 years), of whom 40 had suffered an acute stroke, were independently observed by two medical students, a doctor and a nurse, and categorised as underweight, normal weight or overweight. Body mass index (BMI) was calculated using height and weight. Sensitivity of the informal assessment for correctly classifying the patient as underweight (BMI < 20 kg/m2), normal (20-30 kg/m2) and overweight (BMI > 30 kg/m2) ranged from 64% to 100% and specificity from 71% to 100%. Interobserver agreement between different pairs of observers was moderate to good. An 'eyeball' assessment of nutritional status is valid and reliable enough for use in a multicentre trial of feeding regimens following acute stroke.

Acute Disease↗