Search PubMed⌕ Search

Biomedical subjects

P Nicolopoulou

Publications and source records attributed to P Nicolopoulou.

3 recordsLinked to original sources

Congenital epulis: an ultrastructural and immunohistochemical case study.

We report a case of an otherwise healthy, two days old, female with a a mass derived from the mandible. Light microscopy findings were compatible with the diagnosis of congenital epulis. The lesion showed negative staining for S-100 protein, which is a characteristic finding in cases of epulis and distinguishes it from granular cell tumor. The characteristic electron microscopy findings, as well as other features of epulis in relation to the theories for its possible origin are also reviewed

Female↗

Three-dimensional DNA image cytometry by confocal scanning laser microscopy in thick tissue blocks of prostatic lesions.

DNA ploidy provides important information for the evaluation of the prognosis of prostate cancer. For the purpose of DNA cytometry and nuclear measurements, we developed an image processing system for the acquisition and processing of three-dimensional (3D) images based on confocal scanning laser microscopy (CSLM). The advantage of the CSLM is the preservation of the tissue architecture and the possibility of multilabeling. It is possible to determine both individual nuclear features and cellular features and the degree of the spatial heterogeneity of several markers. Special attention was paid to the development of the automatic method for the 3D segmentation of cell nuclei. Thick tissue slides (100 microm), stained for DNA with chromomycin A3, from 4 patients (with benign hyperplasia, prostatic intraepithelial neoplasia (PIN), and well-and poorly-differentiated adenocarcinoma of the prostate), were studied in order to test the practicability of the developed methodology. DNA histograms showed a single peak in the diploid range for the hyperplasia and PIN cases. For the case of well-differentiated carcinoma, 2 peaks were observed, 1 in the diploid range and I in the tetraploid range. The case of poorly-differentiated carcinoma was characterized by an aneuploid distribution. For the cases of PIN and carcinomas, we observed a considerable variation of the volume of nuclei.

Adenocarcinoma↗

[Overdentures (a case report)].

In this article, the advantages, disadvantages, indications, contraindications, and the details of overdenture treatment are outlined and a case is presented. We prepared an overdenture for a patient who came to the Clinic of Removable Prosthodontics of the University of Athens. The patient had a severe abrasion of his teeth as well as reduced vertical dimension (2.5 cm). The construction was made in such a way that we obtained a good esthetic results with no great expense, as the financial condition of the patient was the factor that influenced the plan of treatment basically.

Aged↗