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Biomedical subjects

P N Zubarev

Publications and source records attributed to P N Zubarev.

At least 19 recordsLinked to original sources
PubMed2002

[Role of the interferon system in the course of neglected forms of colorectal cancer].

Operations for neglected forms of colorectal carcinoma were performed on 66 patients. The interferon status was determined before the operation, on the 1st, 7th and 14th days after the operative intervention. "Viferon-2" was given to 18 patients (starting from 2 days before the operation) with the daily dose 1,000,000 IU. The investigation has shown that deep inhibition of production of interferon (alpha and beta by leukocytes increased risk of the development of postoperative pyo-inflammatory complications. Using the preparation "Viferon-2" is highly effective for prevention of such complications.

Colorectal Neoplasms↗
PubMed2001

[Idiopathic portal hypertension].

The authors present a report of 14 patients with the syndrome of portal hypertension without liver cirrhosis and with recurring esophagogastric bleedings. The cause of the alterations in portal hemodynamics remains unknown. Operative treatments (splenorenal shunts in 9 cases, 3 splenectomies and 1 ligation of the splenic artery) were successful. Two patients in whom splenectomy had been performed in combination with omentohepatopexy died 6 and 10 years after operation due to recurrent hemorrhages. The other patients did not have recurrent bleedings, but in 6 patients 6-10 years after splenorenal shunts there appeared other diseases (encephalopathy, nephrolithiasis, arterial hypertension, duodenal ulcer). The authors consider that indications for shunting operations for idiopathic portal hypertension, especially when using renal veins, should be determined more carefully, phlebosclerotic therapy and transsection of the esophagus being recommended as alternative interventions.

Adolescent↗
PubMed2001

[New surgical methods for treating hepatic hydatic cyst].

The authors have developed a set of instruments for endovideosurgical treatment of hydatid cysts of the liver. It was successfully used in operative ablation of the cysts by a traditional method in 9 patients, and in 7 patients laparoscopic echinococcus ectomy was performed without any complications.

Adult↗
PubMed2000

[The fixed omentum syndrome].

Ten cases of the fixed omentum syndrome which appeared in women operated on organs of the small pelvis are discussed. The cause of adhesions of the greater omentum and the parietal peritoneum and internal organs was the operative trauma in combination with inflammatory alterations of the peritoneum. The surgical treatment consisted in the division of adhesions of the greater omentum, resection of the omentum portion being fulfilled in cases of its cicatricial alterations. Complete healing was noted in all the patients.

Adult↗
PubMed1999

[Combined vagotomy in the surgical treatment of patients with duodenal ulcer].

Short-term and long-term results of surgical treatment of 487 patients with duodenal ulcer were studied. In 337 patients (69.2%) truncal vagotomy was performed; in 94 patients (19.3%)--combined vagotomy; in 56 patients (11.5%)--selective vagotomy. With no lethal outcomes, the frequency of general surgical complications was 5.6% which did not depend on the type of vagotomy. According to the Visick criteria long-term excellent and good results were noted after truncal vagotomy in 90.4% of the patients, after combined vagotomy--in 88% and after selective proximal vagotomy--in 70% of the patients. With the same frequency of recurrent ulcers, diarrhea and dumping-syndrome combined vagotomy has some advantages in recovery of the motor evacuating function as compared with truncal vagotomy; yielding in frequency of diarrhea it has better long-term results by the Visick criteria as compared with selective proximal vagotomy and less frequency of recurrent ulcers.

Dumping Syndrome↗
PubMed1998

[Procedures for the surgical treatment of cancer of the distal portions of the large intestine].

The authors observed 224 patients with neglected forms of carcinoma of distal portions of the colon, 171 (76.3%) of them being considered to be operable. The character of operative interventions depended on neglect of the tumour process which was determined by its spread to the neighbouring organs and tissues. The endolymphatic antibacterial therapy through the inguinal lymph node allowed the perifocal inflammation to be controlled which made the ablation of the tumour and the involved lymph nodes easier. The veritable ingrowth of the tumour into the neighbouring organs and tissues was noted in 15.4% of the patients. Radical operations were performed on 128 patients (74.9%), the other patients were submitted to palliative operations. The strategy of surgical treatment must be based upon the detailed diagnosis of the tumour growth and adequate preoperative preparation including endolymphatic infusions of antibacterial medicine. It allows to increase the amount of radical interventions and widen the indications for performing sphincter-saving operations.

Digestive System Surgical Procedures↗
PubMed1998

[The surgical treatment of cancer of the esophagus and cardia. The complications and hazards].

One-stage operations for carcinoma of the esophagus and cardia were performed on 100 patients. The substitution of the resected esophagus was made with a isoperistaltic tube from the greater curvature of the stomach with anastomosis on the neck, in the pleural or abdominal cavities. Palliative interventions were fulfilled on 31 patients with inoperable carcinomas. An analysis of the structure and causes of postoperative complications and postoperative lethality has shown that among the most frequent causes of deaths in the postoperative period were purulent-infectious complications as a result of ischemia of gastric transplants and incompetence of sutures of the anastomoses as well as pleuro-pulmonary complications. Special attention was given to an analysis of complications after operations performed without thoracotomy from the cervico-abdominal access. The amount of postoperative complications was 30%, postoperative lethality 15%. One-year survival after operations made up 57%, 3-year survival--less than 30%, 5-year survival--less than 15%. Some recommendations are given for the surgical policy and methods of prophylactics of certain complications. Endolymphatic infusions of cytostatics used as adjuvant chemotherapy in complex treatment of patients with cardioesophageal carcinoma represent a perspective direction providing longer life of the patients without recidivations. From the oncological viewpoint the operation without thoracotomy are not always thought to be justifiable.

Cardia↗
PubMed1997

[Digital subtraction arterioportography in the examination of patients with the portal hypertension syndrome].

Based upon data of 107 angiographic examinations in the regimen of digital subtraction the authors propose a regional program of angiographic examinations of patients with the syndrome of portal hypertension including the digital subtraction recurrent celiac and mesenteric portography, terminal occlusive flebohepatography. The given complex of investigations allows the determination with a minimum traumatic action of the form of portal hypertension and selection of the best for each patient kind of operative intervention. The article describes the methods of angiographic examinations improved and adapted by the authors for diagnosing the syndrome of portal hypertension. Criteria for the assessment of the results obtained are proposed. The use of digital subtraction arterioportography in complex with digital occlusive flebohepatography allows the main problems facing the surgeons when choosing the kind of operative interventions for patients with portal hypertension to be solved.

Angiography, Digital Subtraction↗
PubMed1996

[The mental health of surgical patients with combat wounds].

Under analysis were results of examination of 119 servicemen who had got wounds of different degree during military operations. The authors come to a conclusion that mental disorders are a component in semiology of traumatic disease in the wounded. Clinical manifestations were found to correlate with the view of the injuring factor, localization, degree of the injuries combination as well as with specific personal reactions to stress.

Acute Disease↗
PubMed1995

[Gunshot trauma].

Explore the source record for details and available documents.

Blast Injuries↗
PubMed1992

[Simultaneous operations in the surgical treatment of cancer of the esophagus and cardia].

In the clinic one-stage operations for cancer of the esophagus of different localizations and cardia were performed on 63 patients. The substitution of the removed esophagus was fulfilled with an isoperistaltic tube made from the greater curvature of the stomach with anastomosis on the neck or in the pleural cavity. After intrapleural plasty lethality was 21%, after total one with extracavital esophagogastroanastomoses--14%. For prevention of ischemic complications an intraoperative assessment of viability of the transplant was performed with the help of microphotoplethysmography. The authors have shown the advantage of endolymphatic route of administration of cytostatic in 25 patients as compared with the intravenous one.

Anastomosis, Surgical↗
PubMed1992

[The indications and methods for decompression of the gastrointestinal tract in injuries to the abdominal cavity organs].

The article analyses the treatment of 122 patients with injuries of organs in abdominal cavity. One of the most important elements in intra- and postoperative treatment for paresis or paralysis of intestines was an abdominal decompression. Its basic methods were the following: nasoenteral drainage, gastroenterostomy by Iu. M. Dederer's method (31), enterostomy by I. D. Zhitniuk (25), and cecostomy (2). The application of decompression made it possible to treat the patients with severe peritonitis caused by gunshot injuries.

Abdominal Injuries↗
PubMed1991

[Is jejunostomy needed in single-stage plastic operations on the esophagus?].

50 patients with carcinomas or corrosive strictures of the esophagus were operated upon with the simultaneous esophagogastroplasty. At the same time the primary provisional jejunostomy after Witzel was performed on 20 of them in order to ensure an adequate decompression and nutrition at the early postoperative period. In cases of dangerous complications (fistulas of esophagogastrostomies--in 37%, purulent mediastinitis or empyemas--in 14% etc.) the use of jejunostomy allows enteral nutrition to be prolonged up to the moment of the independent oral feeding. It is concluded that the formation of primary jejunostomy for curative and prophylactic purposes is expedient in the simultaneous reconstructive esophageal operations for tumors and strictures.

Esophagectomy↗
PubMed1991

[Prevention and treatment of pleuropulmonary complications after simultaneous reconstructive operations on the esophagus in esophageal cancer].

Pleuropulmonary complications in 50 patients who underwent operation for esophageal carcinoma with simultaneous esophagogastroplasty were most frequent (59%) and serious and accounted for up to 60% of all causes of early postoperative mortality. In operations through a transthoracic approach these complications occur more frequently (75%) than in operations without thoracotomy (48%). The possible causes and measures for the prevention of pleuropulmonary complications in the pre-, intra-, and postoperative periods are discussed. Particular attention is focused on the acute respiratory insufficiency syndrome during resection of the esophagus without thoracotomy. It is concluded that this serious pathological condition can be avoided by a complex of preventive and therapeutic measures carried out in all stages of treatment.

Adult↗
PubMed1990

[Surgical tactics in gunshot wounds of the colon].

Differential surgical tactics was used in 74 wounded patients with injuries of the colon. It allowed to obtain good immediate results. The amount of postoperative complications was 23%, lethality was 12%. The wounds were sutured in 50 patients, among them in 15 patients the sutured parts were extraperitonized, in 21 patients decompression of proximal portions of the gastrointestinal tract was performed. Resection of the right flank with making ileo-transverso-anastomosis was performed in 5 patients, resection of the left flank with a proximal colostomy ++--in 9 patients. Operations of bringing the destroyed portion of the colon onto the anterior abdominal wall were fulfilled on most critically wounded patients.

Anastomosis, Surgical↗