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Biomedical subjects

P N Miller

Publications and source records attributed to P N Miller.

4 recordsLinked to original sources

Stereotypes of the elderly in magazine advertisements 1956-1996.

The globalization of American culture is increasing as various media target an international market. This article reports the results of a study examining trends in the stereotyping of the elderly in print advertisements appearing from 1956 to 1996 in U.S. magazines. Results show that the percentage of elderly portrayals in print ads has decreased. There has been relatively little overall stereotyping of elderly, with only 4 percent of the sample depicting negative stereotypes. Nevertheless, there has been an increasing percentage of negative stereotypes and a decreasing percentage of positive stereotypes. Results are analyzed in relationship to marketing trends and the social impact on aging.

Advertising↗

Growth of 9.5-day rat embryos in folic-acid-deficient serum.

Rat embryos (9.5-day-old) were cultured for 48 hours in serum from diet-induced folic-acid-deficient rats. Resultant embryos were frequently abnormal; many were growth retarded and exhibited a defect in the turning mechanism that inverts the embryo from ventrally to dorsally convex. Affected embryos displayed abnormal twisting or kinking of the neural tube. Gross anaemia was also frequently observed, and the protein content of the embryos was markedly less than that of embryos grown in normal rat serum. Supplementation of the deficient serum with folic acid improved growth and greatly reduced the occurrence of deformities. It virtually eliminated the incidence of gross anaemia but only partially restored the protein content of the embryos to the level observed in those grown in normal rat serum. The effects of the folate deficiency could be eliminated by supplementation with normal rat serum. The data indicate that embryos have a requirement for adequate folate in order for normal growth and differentiation to take place; they also suggest that some of the embryopathic effects of maternal folate deficiency are mediated by secondary effects on maternal metabolism. This may take the form of a disturbance in the production of maternally synthesised growth factors necessary for normal embryonic development.

Animals↗

Sequential production of specific antibodies in serum and at the skin surface of cattle following intradermal vaccination with Dermatophilus congolensis.

Studies of the temporal changes in specific antibody titres to D. congolensis in serum and washings from inoculated and uninoculated skin indicate that production of IgG1 and IgG2 antibody at the skin surface is a transudative process related to serum antibody concentration. Transport of IgM is likely to be based on a similar mechanism but that of IgA appears to depend on a local secretory process.

Actinomycetales↗