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Biomedical subjects

P Myrianthopoulou

Publications and source records attributed to P Myrianthopoulou.

4 recordsLinked to original sources
PubMed2006

Epileptic seizures followed by nonepileptic manifestations: a video-EEG diagnosis.

OBJECTIVE: To present and discuss a case of a woman who for many years was presumed to have nonepileptic seizures (NES), but proved to actually have both electrical and non-electrical seizures, the latter occurring in a close temporal association with the former. To also discuss the seimiology her true as well as NES and compare to other cases identified from a literature review on this subject. MATERIALS AND METHODS: Closed-circuit video-EEG monitoring was performed in order to capture and subsequently analyse the patient's events. RESULTS: During video-EEG monitoring, she proved to have short electrical seizures followed by psychogenic elaborations. Her NES had obscured her true seizures for a number of years. CONCLUSIONS: Psychogenic elaboration of an epileptic seizure (ES) may occur in the same patient and the latter may obscure the former. The use of video-EEG monitoring may delineate the correct diagnosis and help clarify the relationship of the two types of events.

Electroencephalography↗
PubMedDate not supplied

Click evoked neurogenic vestibular potentials (NVESTEPs): a method of assessing the function of the vestibular system.

OBJECTIVES: To obtain neurogenic vestibular evoked potentials (NVESTEPs) with surface scalp recording using high intensity auditory clicks. The same stimulus is used in myogenic vestibular evoked potentials which has been shown to evoke potentials in the vestibular division of the vestibulocochlear nerve. METHODS: A whole head recording with surface EEG electrodes was performed using high intensity clicks in one normal volunteer to determine the best recording position for vestibular evoked potentials. The results were compared to responses at moderate click intensities used for brainstem auditory evoked potentials (BAEPs). The difference in the location of the two responses on the scalp was assumed to be from the vestibular system. RESULTS: Responses specific to the high intensity clicks were best obtained in the parietal areas, with no reproducible responses obtained in the same area with moderate intensity clicks normally used in BAEPs. Recordings in neurologically normal volunteers showed a consistent response with a negative polarity at around 3 ms, which we therefore called N3. Two case studies are presented. The first case is a patient with unilateral sensorineural hearing loss with NVESTEPs present, suggesting that NVESTEPs is not a cochlear response. The second case is a patient with multiple sclerosis with demyelinating lesions in the pons and an unobtainable NVESTEP response. CONCLUSION: NVESTEPs is a possible new diagnostic technique that may be specific for the vestibular pathway. It has potential use in patients with symptoms of dizziness, subclinical symptoms in multiple sclerosis, and in disorders specific for the vestibular nerve.

Adolescent↗
PubMedDate not supplied

Brainstem auditory evoked responses that disappear during sleep: a possible manifestation of a neurogenic vestibular evoked response.

OBJECTIVE: To present a case of unilateral hearing loss in which a brainstem auditory evoked potential (BAEP) disappeared during sleep on the symptomatic side, and to argue that this may actually be a manifestation of a neurogenic vestibular evoked potential (NVESTEP). MATERIAL AND METHOD: Brainstem auditory evoked potentials were performed in the standard manner. RESULT: A poorly organized response was obtained during wakefulness on the symptomatic side that resembled a BAEP. The BAEP for the right ear was better organized. During sleep, the response for the left ear disappeared. CONCLUSIONS: The poor organization of the response of the left ear compared to the right, and its disappearance during sleep, suggests that the response for the left ear was actually an NVESTEP and not a BAEP. The possibility of recording vestibular responses with auditory stimuli may have important implications for BAEP examinations performed during wakefulness that may lead to false negative results, in neonatal screening for hearing loss that use tone stimuli, and also in brain mapping using magnetic resonance imaging (MRI) and positron emission tomography (PET) relating to the auditory cortex.

Child↗