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Biomedical subjects

P Muller

Publications and source records attributed to P Muller.

264 records · Page 15Linked to original sources
PubMedDate not supplied

[Pregnancy and delivery in adolescents. Apropos of 112 case reports].

The authors studied the course of pregnancy in 112 adolescents under the age of 15 years 3 months seen over the last decade. 10% of pregnancies were marked by anaemia, 23% by excessive weight gain and 20% by toxaemia of pregnancy. Although the delivery is often premature, it is usually simple, with rapid labour and expulsion. Forceps were required in 8% of cases and the ventouse was used in 11% of cases. Epidural anaesthesia was performed in 50% of deliveries. Despite an almost normal pregnancy and a eutocic delivery, 21% of babies presented a malformation.

Adolescent↗
PubMedDate not supplied

[Practical thoughts on the matter of responsibility in phlebology].

If the general concept of responsibility has been widening, so, too, the concept of medical responsibility. The changes in outlook may be good for us in that they oblige us personally to keep a check on our medical actions. But they also gradually restrict our medical rights, and our right to make ethical decisions. The most notable points in these changes include the concept of enlightened consent, important considerations of the comparative pros and cons of all treatment or diagnosis; considerations too of the time spent on these, and examinations of our work-methods, and of the means used in our practice. One of the most notable changes concerns the patient-doctor relationship. Taken to extremes, such changes could have a negative and paralysing effect on medical practice, and be detrimental to the patient.

Humans↗
PubMedDate not supplied

In-vitro and in-vivo comparative analysis of four tissue pH monitoring systems.

The purpose of this investigation was to identify the type of pH-reference electrode combination that is the most suitable and reliable in clinical applications involving long-term postoperative monitoring of microvascular reconstructive transplants and diagnosis of compartment syndrome. Four types of pH-sensing devices were chosen for the study: a standard glass pH electrode, a polymer-based pH electrode, an ISFET pH sensor, and a fiberoptic pH sensor. Various combinations of electrodes were tested in vitro for typically four days. The glass and polymer electrodes maintained stable pH readings, averaging drifts of 0.14 +/- 0.07 and 0.14 +/- 0.08 pH units per 96 hours, respectively. The fiberoptic sensors displayed an average drift of 0.20 +/- 0.15 pH units per 96 hours. ISFET sensors displayed nearly linear drifts, averaging 1.36 +/- 0.54 pH units per 96 hours. When placed in healthy animal tissue, glass and polymer electrode pH readings followed the arterial blood pH values, measured by a blood gas analyzer. In compromised tissue, both glass and polymer electrodes recorded falling pH levels correctly, indicating ischemic conditions. Generally, ISFET sensors in healthy tissue produced pH readings that did not correlate well with arterial blood pH values. Fiberoptic sensors monitored healthy-tissue pH correctly; however, mechanical disturbances of the fiberoptic sensor and occasional discontinuation of computer operation would shift the pH output significantly (at times by 0.2 pH units), resulting in subsequent inaccurate pH readings. The glass electrode was the only sensor evaluated clinically. It correctly indicated tissue viability in all clinical cases, involving both healthy and ischemic tissue. The authors conclude that the glass pH electrode has the best combination of characteristics for clinical tissue pH measurements.

Animals↗