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Biomedical subjects

P Monaco

Publications and source records attributed to P Monaco.

27 records · Page 2Linked to original sources
PubMedDate not supplied

[Study of a new hypnotic drug: Ro 5-4200 (flunitrazepam)].

The Authors carried out a clinical study of a new benzodiazepinic derivative (Ro 5-4200) presenting hypnotic properties particularly "interesting". The results emerged from this study confirmed the hypnotic efficacy of the preparation also in case of insomnia of a certain seriousness, as well as its excellent tolerance.

Adult↗
PubMedDate not supplied

[Study of the antidepressive effects of a biological transmethylating agent (S-adenosyl-methione or SAM)].

A research has been made in monotherapy and double blind in order to study the antidepressive effects of S-adenosil-L-methionine (SAMe) on homogeneous groups of patients suffering from relapsing endogenous depression out responding to tryciclique tymoleptiques or suffering from neurotic depression. In this last case the drug in question was being studied against amytriptiline. The antidepressive effects of SAMe have been evident and statistically highly interesting, precocious, free from collateral effects and maniacal rebounds. The sample positive effects were noticed also in those patients not responding to tryclique tymoleptiques. Any biochemical mechanism following the central action of SAMe are being discussed.

Adjustment Disorders↗