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Biomedical subjects

P Metzger

Publications and source records attributed to P Metzger.

44 records · Page 3Linked to original sources
PubMed1976

Incorporation of amino acids into protein of foetal rabbit diaphragm: effect of insulin.

The incorporation of six L-amino acids into the protein fraction of the diaphragm of foetal and neonatal rabbits has been measured. Insulin stimulates the incorporation of lysine from the 29th day and of glycine from the 31st day of gestation onwards. The incorporation of histidine, serine and threonine is only enhanced in the diaphragm of 16-20 hour-old rabbits; no effect of insulin on the incorporation of leucine has been shown for the period under study.

Amino Acids↗
PubMedDate not supplied

Some characteristics of TRH-induced grooming behavior in rats.

Intracerebroventricular administration of TRH induces excessive grooming behavior that is characterized by an important contribution of the elements scratching and paw licking. As compared with other grooming inducing peptides, the pattern of TRH-induced grooming resembles that induced by beta-endorphin rather than those elicited by ACTH or bombesin. TRH-induced excessive grooming is suppressed by pretreatment with haloperidol, naloxone or neurotensin. Haloperidol suppresses TRH-induced grooming in a general way, whereas the suppressive effect of the other drugs is mainly due to a selective reduction of TRH-induced excessive scratching. Combined treatments of rats with TRH and a submaximal dose of ACTH, bombesin or beta-endorphin do not result in higher grooming scores than with single peptide treatment. Excessive grooming elicited by water immersion is not affected by TRH. It is concluded that TRH is undoubtedly an excessive grooming inducing peptide. In situations where excessive grooming is elicited by other peptides or by water immersion, TRH does not further activate the operating systems involved in the existing excessive grooming.

Animals↗
PubMedDate not supplied

Bile duct injuries in the era of laparoscopic cholecystectomy.

By the introduction of laparoscopic cholecystectomy a new field of surgical development has been opened, resulting in the reduction of conventional surgical trauma, and giving the chance to the patient seeking for less postoperative pain, short hospital stay and quick return to activity and work. In spite of these advantages, many laparoscopic cholecystectomy related complications occurred, especially in the period of the learning curve. Due to the special technical requirements, problems of the two dimensional vision, depth perception and hand-eye coordination guided to injuries of the bile ducts, which reached a high rate of 3%. This rate is ten times more when compared with conventional cholecystectomy. The authors present a detailed account of the causes of the injuries, their typical localisation and the best way to avoid and treat them.

Activities of Daily Living↗