Familial multiple naevi flammei.
The third family with multiple naevi flammei and the first description of its occurrence in unidentical twins is presented. Autosomal dominant inheritance is confirmed.
Biomedical subjects
Publications and source records attributed to P Merlob.
The third family with multiple naevi flammei and the first description of its occurrence in unidentical twins is presented. Autosomal dominant inheritance is confirmed.
A newborn infant with postaxial polydactyly of the hands, preaxial polydactyly of the feet, syndactyly and craniofacial dysmorphism (Greig's Syndrome) is reported. The radiographic manifestations in the neonatal period are described. The advanced bone age, the unusual shape of the iliac bones and the supernumerary prehallux toe are new radiological findings in Greig's Syndrome at this age. The diffuse distribution of skeletal anomalies suggests a more complex problem of the intrauterine process of ossification.
Explore the source record for details and available documents.
The present study establishes normal anthropometric standards for head length and head width in newborn infants born between 27 and 41 gestational weeks. These parameters were measured in 198 term and preterm newborn infants, and their relation to head circumference was determined for each gestational week. The results are presented as growth curves for gestational age.
Explore the source record for details and available documents.
The mathematical relationship between blood viscosity and hematocrit levels was studied in 93 venous blood samples drawn within the first 6 hours of life from 20 full-term infants with weight appropriate for gestational age. A highly significant linear correlation (r = .948) between the logarithm of the viscosity at all the shear rates examined and the Hct was found. This indicates an exponential relationship between the blood viscosity and the Hct levels for every value of the Hct greater than 42%. A new dynamic definition of neonatal polycythemia, which takes into consideration the time of sampling, is suggested. By determining the mean + 2 SD, the upper limit of the normal Hct at the age of 2 hours was 71% and at the age of 6 hours was 68%.
The dynamic changes occurring in hematocrit and blood viscosity within the first 18 hours of life were studied in 50 full-term infants who were vaginally delivered and had weight appropriate for gestational age. In all cases, the cord was clamped within 30 seconds and cord blood was collected from the vein and artery. Subsequently, samples were taken from a peripheral vein at ages 15 minutes, and 2, 4, 6, and between 12 to 18 hours. Both the Hct and blood viscosity reach their peak at age 2 hours. The incidence of neonatal polycythemia varied greatly with age. Thus at the age of 2 hours, ten infants (20%) were polycythemic, whereas by age 6 hours only six (12%) of these infants were still polycythemic and by age 12 to 18 hours only one infant (2%) was polycythemic. A linear correlation was found between cord Hct levels and peripheral venous Hct levels by age 2 hours. None of the infants with cord blood Hct levels less than or equal to 56% had developed polycythemia, whereas ten of the 12 infants with cord Hct levels greater than 56% developed polycythemia. In this particular group of infants, cord blood Hct levels may be used for the screening of neonatal polycythemia.
Anterior displacement of the anus is a common cause of constipation in infancy and early childhood. However, normal values are not available for defining anal displacement. Using a simple technique, an anal position index of less than 0.34 in girls and less than 0.46 in boys was indicative of anterior displacement. The diagnosis can be made in the neonatal period.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The present study assists the clinician in determining an abnormal upper limb in the newborn. To define standards for upper limb measurements in the newborn, 198 term and preterm infants (gestational age range, 27 to 41 weeks) were examined. In every case, the gestational age was determined chronologically and clinically, and the total length of the arm, upper extremity and forearm lengths, and total hand and middle finger lengths were measured by two observers using standard techniques. Normal values were determined by plotting the mean +/- 2 SDs for each gestational week v the gestational age.
A prospective study on supernumerary nipples (SNNs) was performed on 1,691 consecutively born neonates. We used a new technique for easier routine detection of SNNs. The incidence of this anomaly was one per 40 or 25 per 1,000 live births. Association of other congenital abnormalities with SNNs was not found.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
In order to define standards for philtrum length and mouth width in the newborn infant, 198 term and preterm infants (27 to 41 gestational weeks) were examined. In every case the gestational age was determined chronologically and clinically and the philtrum length and mouth width (oral intercommissural distance) were measured by two observers using standard measurement techniques. Normal values are presented by plotting the mean +/- 2 SD for each gestational week versus the gestational age.
In order to define normal values for ear length and position in the newborn infant, 198 (87 term and 111 preterm) infants were examined. In every case gestational age was determined chronologically and clinically. Ear length was measured from the superior to the inferior aspects of the ear. Using a horizontal line passing through the inner canthi of the eyes the portion of the ear above this line was measured, determining the position of the ear by its relation to total ear length. Normal values are presented by plotting the mean +/- 2 SD versus the gestational age. Small ears and low set ears are defined as values less than the mean -2 SD.
A high incidence of hymenal tags (5.75%) and hymenal bands (2.7%) was found during the routine physical examination of 974 female infants within the first 24 hours of life. Hymenal tags usually disappear spontaneously as the estrogen effect diminishes. If they do not, biopsy should be considered. A simple test is proposed to demonstrate the superficial position of the hymenal band and its lack of connection with an internal structure.