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Biomedical subjects

P Mazet

Publications and source records attributed to P Mazet.

At least 19 recordsLinked to original sources

Clinical relevance of electroconvulsive therapy (ECT) in adolescents with severe mood disorder: evidence from a follow-up study.

Given the limited knowledge on the long-term outcome of adolescents who receive electroconvulsive therapy (ECT), the study aimed to follow-up adolescents treated with ECT for severe mood disorder. Eleven subjects treated during adolescence with bilateral ECT for psychotic depression (n = 6) or mania (n = 5), and ten psychiatric controls matched for sex, age, school level, and clinical diagnosis, completed at least 1 year after treatment a clinical and social evaluation. Mean duration between time of index episode and time of follow-up evaluation was 5.2 years (range 2-9 years). At follow-up: (1) all patients except two in the control group received a diagnosis of bipolar disorder. (2) Fifteen patients had had more than one episode of mood disorder. (3) The two groups did not differ in social functioning nor school achievement. (4) Impact on school achievement was related to the severity of the mood disorder rather than ECT treatment. The results suggest that adolescents given ECT for bipolar disorder, depressed or manic, do not differ in subsequent school and social functioning from carefully matched controls.

Achievement↗

Electroconvulsive therapy in adolescents with mood disorder: patients' and parents' attitudes.

The aim of the study was to assess retrospectively patients' and parents' experiences and attitudes towards the use of electroconvulsive therapy (ECT) in adolescence. The experiences of subjects (n=10) who were administered ECT in adolescence for a severe mood disorder and their parents (n=18) were assessed using a semi-structured interview after a mean of 4.5 years (range, 19 months to 9 years). Their attitudes were mostly positive and ECT was considered a helpful treatment. Concerns were frequently expressed, probably because ECT was not fully understood by the patients and their families. Most complaints were of transitory memory impairment. The parents were satisfied with the consent procedure, while all but one patient did not remember the consent procedure. We concluded that, despite negative views about ECT in public opinion, adolescent recipients and their parents shared overall positive attitudes towards the use of ECT in this age range.

Adolescent↗

Borna disease virus and psychiatry.

Borna disease virus (BDV), a noncytolytic neurotropic nonsegmented negative-stranded RNA virus with a wide geographic distribution, infects several vertebrate animal species and causes an immune-mediated central nervous system (CNS) disease with various manifestations, depending on both host and viral factors. In animal infections, BDV can persist in the CNS and induce alterations in brain cell functions, neurodevelopmental abnormalities and behavioral disturbances. An association between BDV and psychiatric disorders (essentially schizophrenia and affective disorders) has been suggested by some serologic and molecular studies but further investigations are required to substantiate the possible contribution of this virus to the pathogenesis of these disorders.

Autistic Disorder↗

[A French classification of mental disorders in children and adolescents].

A French classification of child and teenage mental problems is presented. It is biaxial; a glossary is included. The motives and options that went into its creation and differences with existing classifications are specified. Equivalencies with CHO project ICD-10 have been set up. The results of a first trial by child psychiatrists are commented on.

Adolescent↗

[Theoretical viewpoints in psychosomatic medicine. The historical and current aspects].

Everyday cases, clinical experience, and some experimental data show that emotional life has significant and varied expressions in the body: behaviours expressed somatically, "functional" visceral disorders, and even "organic" diseases. To explain these findings, various theoretical concepts have been or are currently put forward. Taking the basic hypothesis of psychosomatics, i.e. the notion of a psyche-soma functional unit, as a starting point, the author considers these main concepts under three different lightings, which are related to the methodologic conditions under which facts are studied: 1) the physiologic approach, which underscores the significance of psychophysiologic interactions, emphasizes either the results of conditioning or those of emotions, according to the case; stress is considered under this angle; 2) the psychological approach, according to the point of view, emphasizes the following notions: life event, subjective experience, personality profile, specific conflict, conversion or regression, defective mentalization; 3) the sociologic and ecologic approach focuses on the relationships between the individual and his surroundings and gives predominance to the notion of environment factors. After a few considerations on the concept of disease and the notion of etiologic multideterminism it is recalled that therapeutic effectiveness stems from the ability to take into account both bodily and psychic distress.

Disease↗

[To be (a girl) or not to be! Or the sex of the angels? Problems in individuation (and identification) in a 3-year-old child. Case report, theoretical comments, treatment].

During a lengthy hospitalization in a pedopsychiatric department, with an intermediate several-week period at home, a child seen at the age of three with severe disorders of relationships and identity was able to progress significantly and to improve organization of personality. The authors report this case and show that this child's problems are largely due to the distortion of family relationships and personal identification problems of the two young parents who were unable to assume freely their own parental role for this child.

Child, Preschool↗

["How goes it, Awa?" Nutritional deficiency, emotional deprivation, severe depressive state in an child under 2 years of age. Diagnostic and therapeutic problems].

The authors report a very illustrative case of analytic depression in an infant under two years of age. The significance of this observation is in the overwhelming nature of symptoms with a characteristic marasmus syndrome fitting classic descriptions, and in the deliberate approach which led a pedo-psychiatric team to an understanding of the problems and to a rapid and dramatic reparation. By the ascription of a significant role to the impact of mother-child, mother-family and social circle relationships, involved members were able to determine their place and reassume their role and function. This approach also draws attention to the susceptibility and vulnerability of children to separation and severance of bonds.

Acculturation↗

[Crises in adolescence. Value of a specialized hospitalization unit].

Hospitalization of a disturbed adolescent is not necessarily a distressing experience. It may provide the opportunity for the separation-individuation process to develop. The various possibilities offered by the Adolescent Psychiatric Unit at the Salpêtrière Hospital are described. The outcome of hospitalization is often gradual autonomy of the adolescent in his family. The functioning of the Unit is illustrated by three clinical reports.

Adolescent↗

[Psychiatric emergencies in childhood and adolescence].

The referrals for urgent psychiatric treatment were studied systematically to improve our understanding of the acute forms of psychological distress in children and adolescents and the crisis situations which disrupt the usual relationships between the child and his family. During the last 12 months, 212 requests for urgent psychiatric opinion in children under 18 years of age were received. The following points were analyzed: --general: age, sex, geographical distribution of the patients and their families, present family conditions, socio-economic class, origin of the urgent referral; --psychological or psychopathological: presenting symptoms, organisation of the personality of the child or adolescent, previous psychological or psychiatric history; --practical: the emergency management, ulterior orientation. The authors conclude with some remarks on the possible lines of action in the emergency situations.

Acute Disease↗