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Biomedical subjects

P Masand

Publications and source records attributed to P Masand.

17 recordsLinked to original sources
PubMed1995

Sleepwalking.

Sleepwalking is one of the parasomnias, a group of disorders that also includes night terrors, nocturnal enuresis and nightmares. This disorder of arousal is much more common in children than in adults, and it is commonly associated with other parasomnias. Sleepwalking typically occurs during the first three hours of sleep, when sleep stages 3 and 4 (non-rapid-eye-movement sleep) are most prevalent. The episodes usually last 30 seconds to 30 minutes. The differential diagnosis of sleepwalking includes partial complex seizures occurring during sleep, rapid-eye-movement behavior disorder, night terrors, malingering, dissociative phenomena and medication effects. The treatment of sleepwalking in children includes providing a regular sleep-wake schedule, ensuring that the child has sufficient sleep and reassuring the parents. Medications and psychotherapy may be indicated in some adult patients.

Adult↗
PubMed1992

An unusual variant of Capgras syndrome.

In a 40-yr.-old man a variant of Capgras syndrome called reverse subjective doubles is described. The unusual feature of the case was the presence of a delusion that the patient had been transformed into someone else.

Adult↗
PubMed1991

Psychostimulants for secondary depression in medical illness.

The hospital charts of 198 patients with acute medical or surgical illnesses who had been treated with either dextroamphetamine or methylphenidate for secondary depression during a 5-year period at the Massachusetts General Hospital were examined. Eighty-two percent of patients showed improvement following psychostimulant treatment. Seventy percent of all patients demonstrated marked or moderate improvement in depressive symptoms. No significant differences in efficacy between the two psychostimulants or across diagnostic categories for depression were observed. Patients improved quickly, usually within the first 2 days of treatment. Adverse reactions necessitating the termination of psychostimulant treatment occurred in 10% of trials. Anorexia was not observed as a side effect of treatment.

Adult↗
PubMed1991

Psychostimulants in post-stroke depression.

The hospital charts of 17 patients with post-stroke depression who were treated with either dextroamphetamine or methylphenidate during a 5-year period at the Massachusetts General Hospital were examined. Eighty-two percent of the patients showed improvement after psychostimulant treatment. Forty-seven percent of all patients showed marked or moderate improvement in depressive symptoms. The authors saw no significant differences in efficacy between the two psychostimulants or across the diagnostic categories for depression. Patients improved quickly, usually within the first 2 days of treatment. Adverse reactions necessitating the termination of psychostimulant treatment occurred in three patients. Anorexia was not observed as a side effect of either dextroamphetamine or methylphenidate treatment. Psychostimulants appear to be a safe and rapidly effective alternative to tricyclic antidepressants in inpatients with post-stroke depression.

Aged↗
PubMedDate not supplied

Psychostimulant treatment of geriatric depressive disorders secondary to medical illness.

The records were reviewed for 129 medically ill geriatric inpatients treated with either dextroamphetamine or methylphenidate for secondary depression during a five year period at the Massachusetts General Hospital. Eighty-one percent of patients demonstrated at least some improvement following psychostimulant treatment. Sixty-six percent of these experienced marked to moderate amelioration of their depressive symptoms. Improvement was rapid and usually occurred within the first or second day of treatment. No significant difference in efficacy was noted between the two psychostimulants or across diagnostic categories for depression. Only 8% of patients experienced adverse reactions significant enough to warrant termination of the psychostimulant trial. No instances of anorexia due to psychostimulant treatment were observed.

Age Factors↗