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Biomedical subjects

P Marcus

Publications and source records attributed to P Marcus.

47 records · Page 3Linked to original sources
PubMed1978

Serum enzyme levels during experimental hypothermia in man.

Deep surgical and accidental hypothermia cause elevations in serum enzyme levels, probably because of ultrastructural cell damage. Many variables hinder work on this problem in the clinical situation and the mechanism is obscure. Accordingly, enzymes and other physiological parameters were monitored in four subjects cooled four times, under controlled conditions in the laboratory, to a mean auditory canal temperature of 35.0 degrees C. Mild hypovolaemia and acidosis is occurred. Serum enzyme levels did not change significantly and it is concluded that elevations due to hypothermia cannot be studied in laboratory experiments on healthy volunteers who can only safely be cooled to 35 degrees C.

Adult↗
PubMed1978

Effect of clothing insulation beneath an immersion coverall on the rate of body cooling in cold water.

Deep body and skin temperatures were measured on nine subjects during a 1 h immersion in water at 2.5 degrees C whilst wearing an RAF Mark 10 immersion coverall. With no additional insulation, mean skin temperature fell 13.1 degrees C and deep body temperature 0.74 degrees C. When a full Acrilan pile suit was worn beneath the coverall mean skin temperature fell 8.3 degrees C and deep body temperature 0.33 degrees C. With insulation covering the trunk and upper limbs alone, mean skin temperature fell 9.9 degrees C and deep body temperature 0.45 degrees C. Conclusions are drawn concerning the effects on body cooling of changes in insulation of aircrew clothing assemblies designed to protect against immersion in cold water.

Adipose Tissue↗
PubMed1978

Laboratory comparison of technique for rewarming hypothermic casualties.

The efficacy of inhalation, hot bath, piped suit and spontaneous rewarming have been directly compared under controlled conditions. Hot bath rewarming was significantly more effective at raising deep body temperature than the piped suit technique and both were more effective than the other two methods. The effect of inhalation rewarming was not significantly different from that of spontaneous rewarming. All techniques gave rise to afterdrops of core temperature of widely varying degrees and durations. It is concluded that inhalation rewarming should not be employed if it entails a delay in transporting a patient to a facility for rapid external rewarming. Piped suit rewarming is a convenient field alternative to the use of a hot bath and a simple apparatus for carrying this out is described. The sluggish response of rectal temperature to cooling and rewarming in this study suggests that it should not be relied upon as the sole indicator of a patient's thermal state during treatment. Auditory canal temperature is a more valid substitute.

Adolescent↗
PubMed1977

Thermal data from helicopters operating in a sub-arctic environment.

Using automatic and observer-operated equipment for monitoring thermal data, observations have been made during Royal Navy Wessex 5 helicopter operations in a sub-Arctic climate. Measurements were taken in flight of front and rear cabin temperatures and aircrew deep body and skin temperatures. The results indicate that the "arcticised" aircraft used had more than enough cabin heating to alleviate cold stress on the aircrew.

Aerospace Medicine↗