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Biomedical subjects

P Marchand

Publications and source records attributed to P Marchand.

At least 55 records · Page 3Linked to original sources

[Evaluation of the activity and quality of care in a digestive surgery department].

Since 1980, details of all patients operated upon in a digestive surgery unit have been entered on record-cards with the view of obtaining information on the activity of the unit and improving post-operative care. Over a 3-year period, 2005 patients underwent surgery, 25% of them for cancerous lesions. Biliary tract operations (385 patients), fundoplication by the abdominal route for gastro-oesophageal reflux (58 patients) and curative resection of the colon for carcinoma (100 patients) were set apart for evaluation. For each of the above pathologies, morbidity, mortality and duration of stay in hospital in cases with uneventful or complicated post-operative course were analyzed. Annual audits of this kind result in accurate evaluation and periodical reappraisal of the therapeutic habits of the medico-surgical team.

Adolescent↗

[Completed calibrated fundoplication].

Complete fundoplication at present is the most effective surgical treatment of gastro-oesophageal reflux. However, it has a number of side-effects, including post-operative dysphagia, inability to eructate and painful gastric distension. Fifty-five patients were operated upon using a technique which comprises wide gastric release and fabrication of a tension-free valve around a 50F probe introduced through the mouth. After 1 year, 94% of patients were free of reflux and 22% had mild dysphagia. After 3 years, the proportion of reflux-free patients still was 94%; 12% suffered from mild dysphagia and 6% had problems with eructation. Thus, calibration of the oesophagus with a 50F probe reduces the side-effects of complete fundoplication while remaining effective against gastro-oesophageal reflux.

Esophagus↗

[The irrigraphic profile, an orienting element in the indications for lumbar sympathectomy].

A retrospective study of 108 case-reports of patients treated by lumbar sympathectomy was conducted to determine irrigraphic parameters possessing possible predictive value for the indication of sympathectomy. The value of the Index 6 (distal irrigation index) must be certainly taken into account; the Index 1 (proximal index) appears to be of interest when analyzing data with a view to sympathectomy in diffuse forms of arteritis. Three profile-types were distinguished; statistical analysis showed no significant difference in these profiles, with respect to the sympathectomy, in relation to the clinical results obtained. Irrigraphic modifications after sympathectomy were analyzed in 72 cases; results confirmed the improved efficacy of sympathectomy at Stage 2 than at Stages 3 and 4, but also showed that at Stage 2 the profile II appeared to react more favorably and that at Stages 3 and 4 the profile I appears to react less well than the other profiles. Also studied were patients with diabetes, who react less favorably to sympathectomy, patients who fail-to respond to sympathectomy, and those with worsening of irrigraphic profiles after sympathectomy, mainly in diabetics with profile I. These findings show that it is not possible to define a precise irrigraphic profile more favorable to sympathectomy, but that they provide interesting elements to be confronted with clinical and arteriographic data when deciding on the need for sympathectomy.

Adult↗

Artistic style and personality in creative painters.

The present study attempted to demonstrate a correspondence between artistic style and the personality of the creator. Personality style, defined as a cognitive-affective system of defenses and controls, was identified for 20 renowned painters through an analysis of their individual Rorschach protocols. Their creative work was classified independently by a jury of 4 persons (one art critic; two eminent painters and the junior author) into stylistic categories similar to those elaborated by the senior author for the Rorschach. The overall correspondence achieved was statistically significant (.72, p < .01), with individual correlations ranging from .75 to .86 (p < .01).

Journal Article↗

[Genesis and clinical aspects of functional diseases].

A new approach of patients with functional disorders is proposed, as a result of an original experience: within a Department of internal Medicine we created a permanent place for listening to patients. This work is devoted to the genesis and clinical aspects of functional disorders. At the start, the functional disorder is bipolar, but meeting the psychotherapist introduces a third dimension. We enlight the specificity of somatization in functional disorders.

Adult↗

[A clinical trial of bromazepam (author's transl)].

Bromazepam was studied in 32 patients with neurotic anxiety. Daily doses varied between 6 and 12 mg on average. Bromazepam was associated with neuroleptic drugs in 2 cases and with tricyclic antidepressants in 12 cases. Satisfactory results were obtained in 72% of the patients, particularly those with anxiety neurosis and reactional anxiety. The drug was tolerated; transient drowsiness was well noted in 3 cases and some degree of euphoria in 2 cases. Bromazepam appears to be a quick-acting, purely anxiolytic drug, with effects perceptible after 2 or 3 days of the treatment. Its lack of sedative action makes it particularly useful in ambulatory patients.

Adolescent↗

Surgical treatment of postphlebitic syndrome with vein valve transplant.

Sequelae of the postphlebitic syndrome can new be treated by direct valve surgery. The present surgical treatment of stasis ulcer, including removal of the incompetent perforators, ulcer excision, and skin grafting, remains essential. Excision of perforators and ulcer care are effective but are associated with a high rate of ulcer recurrence. Experimental studies to restore venous valve function include autogenous or homologous vein valve transplantation, valvuloplasty, and valve transposition. In 23 cases of vein valve transplantation and two transpositions, a normal autogenous vein valve from the arm was used to restore a normal functioning venous valve in the leg. Pre- and postoperative noninvasive and invasive testing indicates hemodynamic improvement of venous function in these legs. Follow-up direct venous pressure measurements did not show normalization and may indicate that more than one competent valve is necessary. Changes in muscle structure may play a role in the maintenance of venous pressure.

Adult↗

Vein valve transplant.

The sequelae of deep vein thrombophlebitis, such as postphlebitic syndrome with or without ulcer, can be treated by direct surgery on the valve. The present surgical treatment of stasis ulcer includes removal of the incompetent communicating veins with excision of the ulcer and skin graft. If this operation is performed on patients who actually have deep venous incompetence, then a high incidence of reulceration and skin graft slough may be expected if there is no concommitant correction of deep venous incompetence. Experimental studies to restore venous valve function such as autogenous vein valve transplant, valvoplasty, homologous vein transplant, and synthetic valve procedures have been tried. It has been shown that with autogenous vein graft there are a lower incidence of thrombosis and a more effective restoration of valve competency than with other procedures. We operated on six patients utilizing an autogenous vein valve from the upper extremity to achieve hemodynamically functioning venous system of the lower extremity. Data on pre- and postoperative noninvasive evaluations and ascending and descending venography with the results of surgery will be discussed.

Adult↗