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Biomedical subjects

P Marceau

Publications and source records attributed to P Marceau.

22 records · Page 2Linked to original sources

Short-term antibiotherapy for peritonitis: prospective, randomized trial comparing cefotaxime-metronidazole and clindamycin-tobramycin.

The combination of cefotaxime and metronidazole has been suggested for the treatment of peritonitis. We compared their effectiveness with that of tobramycin and clindamycin. Since antibiotics have most of their beneficial effect within a few days a four day course was used and a randomized trial was undertaken. The effectiveness of the 4-day course was 86% and no difference was seen between the two groups of the study.

Cefotaxime↗

[Pleural effusion indicator of pancreatitis].

The presence of a pleural effusion in patients with pancreatitis is a common marginal occurrence. On rare occasions the pleural effusion not only is abundant, recurrent, hemorrhagic and contains a high concentration of amylase, but presents as the only manifestation of an otherwise undiagnosed or obscure pancreatitis. Thus it presents a difficult diagnostic and therapeutic problem. The authors report such a case and review the literature in which 49 cases have been reported in the past 10 years. Pancreatomediastinopleural fistula is usually visualized and seems to be the basic fault in most cases. Thoracic drainage will relieve the patient and dry up the effusion in one third of cases. Otherwise pancreatic resection is usually required. Internal or external drainage of the mediastinopleural component by laparotomy is not difficult. Pleural sequelae are minimal in most cases.

Humans↗

Experience with hyperselective vagotomy in patients with duodenal ulcer.

Hyperselective vagotomy is a relatively recent surgical procedure used for the treatment of duodenal ulcer. We report excellent results in 98 consecutive patients during the last four years. After a mean follow-up period of 2.2 years, the results, according to the classification of Visick, are excellent in a large number of patients. There was a significant gain in body weight in a majority of the patients. The recurrence rate for an ulcer is only 4.5 per cent. There is a significant reduction of basal acid output of 63 per cent, maximal acid output of 46.8 per cent and postinsulin acid output of 73.7 per cent.

Adult↗