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Biomedical subjects

P Mannella

Publications and source records attributed to P Mannella.

At least 37 records · Page 2Linked to original sources

[Selective arteriography in fractures of the femur head].

The choice between conservative and radical operation in case of femoral neck fractures is very important because it is the determining factor for a successful therapy. In case of epiphysial necrosis, an endoprosthesis as well as an osteosynthesis will be carried out. Selective arteriography of the medial circumflex artery represents the most reliable study to establish, immediately after the fracture, the possible presence of a post-traumatic ischemic necrosis. Angiography, as a reliable diagnostic tool, has to be carried out in the most selective way and needs the image subtraction technique. The authors report their preliminary results on the reliability of angiography in the femoral epiphyseal ischemic necrosis diagnosed by comparing the results of angiography with the Wood light test carried out on the surgically removed femoral head.

Adult↗

[Culture studies of the bile during transhepatic cholangiography].

A bacterial examination was carried out on bile taken from 119 patients undergoing transhepatic percutaneous cholangiography (P.T.C.) due to biliary obstruction. Bacteria were found in 36.9% of cases, with greater frequency in cases of benign obstructions (69.6%) than malignant obstructions (27.2%). The extent of obstruction was found to make no difference (stenotic or obstructive). These results therefore confirm that a risk of infectious complications during P.T.C. exist. Susceptibility studies carried out on bile bacteria showed gentamycin to be the most effective antibiotic in the prevention and treatment of infection in these cases.

Adult↗

[Xeroangiography. Technical principals and applied developments].

The physical patterns ruling the information of a xeroradiographic image allow the visualization of the arterial system with a lower concentration of contrast medium. So you can visualize the arterial branches both with intravenous injection of the usual angiographic concentration of contrast medium or with intraarterial injection of diluted contrast medium at a very low concentration. A prerequisite to successful xeroangiography was the commercial diffusion of a changer for xerox cassettes allowing several exposures according to standardized programs.

Angiography↗

[Transvenous xeroangiography of arteriovenous fistulas of patients undergoing periodic hemodialysis].

Xeroradiography allows visualisation of the arterial system after intravenous injection of contrast media. This method has proved particularly useful for diagnosis of changes in the arteriovenous fistulas of 20 patients on chronic haemodialysis. In all cases transvenous xeroangiography gave information about morphologic alterations of vessels and soft tissues. Among the commonly used angiographic methods, transvenous xeroangiography appears the technique of choice.

Aged↗

[Changes in thyroid hormone status after injections of iodinated contrast media].

Administration of four different contrast media exerted slight but significant and prolonged effects on the hormonal thyroid status, in 53 euthyroid subjects (four subgroups), without any clinical expression of dysthyroidism. Changes in serum T3, rT3 and T4 demonstrated different trends for each iodinated compound, probably depending on the regulatory thyroid mechanisms, and CM pharmacokinetics. Plasma profiles of free fractions (FT3, FT4) slightly reflected consensual changes with circulating iodothyronines, at various time periods of study, demonstrating high correlation indexes with total fractions. The five hormones profiles correlation study suggest that different mechanisms could be responsible for some features encountered of "low T3 syndrome". These effects may be not only equivalent to giving various sources of iodide, but suggest more complex mechanisms. It is apparent that man has a remarkable and possibly unique system of homeostatic thyroid hormone regulation.

Angiography↗

[Embolization in bladder hemorrhage of neoplastic origin].

The authors report on their two years experience about hypogastric transarterial embolization in the treatment of urinary bladder intractable neoplastic hemorrhage. They discuss about materials for embolization and treatment of pain for acute ischaemia secondary to embolization.

Embolization, Therapeutic↗

[Value and limits of echography and abdominal lymphography in malignant lymphomas].

Diagnostic results obtained by echography and lymphography in the study of abdominal lymphoglandular involvement in patients with lymphomas are compared. The data indicate that while lymphography is more revealing, the two examinations should be used together in staging. Echography, on the other hand, should be used for long-term surveillance, once the lymphographic contrast medium has been absorbed.

Female↗

[Renal contrast radiography study in hypertensive patients: comparison of the nephrotoxicity of ionic and non-ionic contrast media].

The results of a study carried out on 32 patients with arterial hypertension about nephrotoxic effect obtained with a new non-ionic contrast agent have been reported. The diagnostic approach was based on the determination of the urinary excretion of two characteristic enzymes of the proximal tubule-epithelial cells (alfa-glycosidase and gamma-glutamil-transferase) and of a microprotein (beta-2-microglobulin) filtered by glomeruli and readsorbed and catalized by epithelial cells. The method used show an increased sensitivity and reliability in the early recognition of a kidney damage as well as in the control of anatomic and functional changes, in comparison with the classic parameters (azotemia, creatininemia). The results show a significantly lower enzymuric and microproteinuric level using non-ionic contrast media, also, in the patients at relatively higher risk of kidney damage. This results should be interpreted in favour to a lower potential nephrotoxicity of non-ionic contrast media and their elective use in the patients with a higher risk of kidney damage.

Adult↗

[Aortic aneurysms as complication of bacterial endocarditis. Report of two cases (author's transl)].

The authors report on two cases, one of supravalvular aortic aneurysm and one of subvalvular aortic aneurysm. Both patients suffered from bacterial endocarditis of the aortic valve, superimposed on previous rheumatic valvular disease. The authors believe that such aneurysms represent typical though rare complication of bacterial endocarditis of the aortic valve. Subvalvular aneurysms should be the consequence of the systolic stress acting on the myocardial wall involved by endocarditis, whereas supravalvular aneurysms could result from the jet-lesion through the affected valve.

Adult↗

[Radiology of the thoracic duct in liver cirrhosis (author's transl)].

The authors on the ground of the lymphographic patterns of 54 cirrhotic patients have emphasized the morpho-functional alterations of the thoracic duct of this patients on the basis of three different parameters: 1) morphology of the thoracic duct; 2) dilatation of the thoracic duct; 3) mouth of the thoracic duct.

Humans↗

[Anti-edema activity of injectable Venoruton in abdominal surgery].

The anti-oedema activity of an injectable drug (HR; active principle: 0-(beta-hydroxyethyl)-rutoside) was assessed in 60 gastric extrahepatic bile duct, and large intestine surgery patients (30 being used as controls). Gastroscopy (with biopsy), gastroduodenoscopy, colonoscopy (with biopsy) and radiological examination were usually performed on the 5th and 10th post-operative days. The drug showed significant therapeutic effects: rapid resolution of oedema, especially at the sutures, leading to early cicatrisation, canalisation and the prevention of dehiscence. Finally, duration of hospitalisation was less than in the untreated cases. The gastroscopic, radiographic and biopsy findings are considered to have shown clear evidence of the drug's action against oedema formation.

Adult↗