Biomedical subjects
Publications and source records attributed to P Mancini.
It is known that the myocardial infarction may be associated with left intraventricular thrombosis (LIT) as the anatomopathologic studies and the heart surgery operations confirmed. The authors verified in this study the incidence and the complications of de LIT in the patients with acute myocardial infarction treated with low-dose heparin.
The Meckels divetriculum has a prevalence of the 0.3-3%. It is surgically removed only when arise a complication or a neoplasia. The Meckels diverticulum tumors are unfrequent and observed in only the 0.5-3.2% of the Meckels diverticula. The 12% of these tumors are a GIST. We report a case of a gastrointestinal stromal tumor with neural immunophenotype, observed in a patient presenting a deep venous thrombosis perhaps with a paraneoplastic origin. We also report some observations about the state of the art about the GIST management and particularly of all of them arising in a Meckels diverticulum.
BACKGROUND AND AIMS: Due to the rarity of the condition, large and prospective series defining the optimal method of digestive arteries revascularization, for the treatment of chronic intestinal ischemia, are lacking. The aim of this consecutive sample clinical study was to test the hypothesis that flexible application of different revascularization methods, according to individual cases, will yield the best results in the management of chronic intestinal ischemia. PATIENTS AND METHODS: Eleven patients, of a mean age of 57 years, underwent revascularization of 11 digestive arteries for symptomatic chronic mesenteric occlusive disease. Eleven superior mesenteric arteries and one celiac axis were revascularized. The revascularization techniques included retrograde bypass grafting in 7 cases, antegrade bypass grafting in 2, percutaneous arterial angioplasty in 1, and arterial reimplantation in one case. The donor axis for either reimplantation or bypass grafting was the infrarenal aorta in 4 cases, an infrarenal Dacron graft in 4, and the celiac aorta in one case. Grafting materials included 5 polytetrafluoroethylene (PTFE) and 3 Dacron grafts. Concomitant procedures included 3 aorto-ilio-femoral grafts and one renal artery revascularization. Mean follow-up length was 31 months. RESULTS: There was no operative mortality. Cumulative survival rate was 88.9% at 36 months (SE 12.1%). Primary patency rate was 90% at 36 months (SE 11.6%). The symptom free rate was 90% at 36 months (SE 11.6%). CONCLUSIONS: Direct reimplantation, antegrade and retrograde bypass grafting, all allow good mid-term results: the choice of the optimal method depends on the anatomic and general patients status. Associated infrarenal and renal arterial lesions can be safely treated in the same time of digestive revascularization. Angioplasty alone yields poor results and should be limited to patients at poor risk for surgery.
METHODS: A series of 9 patients of a mean age of 48 years, operated on for compression of the ilio-femoral venous axis is reported. The cause of obstruction was external compression in 3 cases, a retroperitoneal sarcoma in 1 case, and an infrarenal aortic aneurysm in 2. Two patients presented with a Cockett's syndrome, 3 with a chronic ilio-femoral thrombosis, and one with a post-traumatic segmentary stenosis. Treatment consisted in a resection/Dacron grafting of 2 infrarenal aortic aneurysms, one femoro-caval bypass graft, 2 transpositions of the right common iliac artery in the left hypogastric artery for Cockett's syndrome, 3 Palma's operations for chronic thrombosis, and one internal jugular vein interposition for segmentary stenosis. RESULTS: There were no postoperative deaths and no early thromboses of venous reconstructions performed. All the patients were relieved of symptoms during the follow-up period, whose mean length was 38 months. CONCLUSION: The cause of venous obstruction and the presence of symptoms which are resistant to medical treatment are the main indications to ilio-femoral venous revascularization. The choice of the optimal treatment in each single case yields satisfactory results.
AIM: The purpose of this study is to evaluate the condylar position and its variation in patients with temporomandibular joint (TMJ) disorders before and after therapy with occlusal gnathologic devices. METHODS: Twenty-five TMJ of 25 patients with temporomandibular joint disorder were examined by linear measurement of the anterior, posterior and superior joint space between the condyle and glenoid fossa through cephalometric analysis on X-ray tomography of the TMJ and by calculating the condylar position with the Pullinger and Hollender method. RESULTS: The average condylar position in the TMJ with DTM was posterior with a mean value of 22.2% and a range from 14.3% to 36%. The condylar position of 25 TMJs was: anterior 0(0%); centric 8(32%) and posterior 17(68%). After therapy with occlusal gnathologic devices the average condylar position was centric with a mean value of 0.6% and a range from 5.3% to 6.6%. The condylar position of 25 TMJs was: anterior 2(8%); centric 22(88%) and posterior 1 (14%). CONCLUSIONS: The hypothesis can be advanced that joint pathology is the consequence of the alteration of the condyle position and therefore of the mandibular movement and vice versa. Therapy with occlusal devices makes it possible to modify the condylar position by increasing the condylar capability to recapture the joint disc.
In this study the authors evaluate the potentiality of two-dimensional echocardiography to detect the left ventricular thrombus in the myocardial infarction. The authors emphasize the morphological echocardiographic patterns suggestive of the high embolic risk of the ventricular thrombus.
In this study the authors compare the Ejection Fraction (EF) as determined by the Single Plane Ellipse Echocardiographic method versus the Ventriculographic EF. The authors emphasize the validity of the two-dimensional echocardiography to assess left ventricular EF in order to improve the clinical and pharmacologic management of the patients with the cardiac ischaemic disease.
In spite of the current availability of new and more up-to-date methods of prevention, diagnosis and therapy, specific forms in general and the ability to perform rapid, efficacious and resolutory operations, a number of cases of subprimary or secondary tuberculosis still exist which are most probably the result of delayed diagnosis, contagious episodes or the failure to adhere to recommended treatment protocols and, often, less than optimum medical therapy. A rare case of adrenal tuberculosis diagnosed in a patient hospitalized for left renal calculosis is reported. Routine tests indicated a specific form of diagnosis, and during surgery for left renal calculosis the patient underwent left adrenalectomy. Histological tests confirmed the initial diagnosis. For 180 days after the operation the patient received pharmacological treatment directed specifically against Koch's bacillus.
A case of an acute aortic dissection (AAD) has been reported in a 61-year-old woman, in whom, by the mono and two-dimensional echocardiography (M and 2D E) the authors have detected: 1) The disconnection between the intima and adventitia. 2) A flap of the intima in the aortic cavity. The authors emphasize the usefulness of the M and 2D E because it permits: 1) An early diagnosis of the AAD. 2) A reduction of the lapse between the angiographic examination and the surgical therapy. 3) A better prognosis.
The authors report a case of Infective Endocarditis (IE) to emphasize the most characteristic echocardiographic features that permit to detect the tricuspid valve involvement in IE, the management of the medica and/or surgical therapy of this disease and the limitations of this noninvasive technique.
All CO2 in blood is in equilibrium, catalyzed by carbonic anhydrase (CA). This has prompted some investigators to consider treating ventilatory failure by using dialysis to remove HCO3-. Since there is at least 18 times more CO2 in the form of HCO3- than dissolved CO2, theoretically, lower blood flows could be used than with current extracorporeal support with artificial membrane lungs. HCO3- removal for ventilatory support has required alkalinization to compensate for the resulting acidosis and has been capable of removing 26 to 38 ml CO2/100 ml blood flow, compared to 14 ml CO2/100 ml for clinically employed silicone membrane lungs. We designed a HCO3- removal system using recirculation of dialysate through a membrane lung to remove CO2, rather than alkalinization of blood, and removed 8.8 ml CO2/100 ml. Adding CA improved this to 12.2 ml CO2/100 ml, but a conventional hollow fiber lung removed 30 ml CO2/100 ml. We conclude that the complexities of an HCO3- removal system may not be necessary with the advent of more efficient hollow fiber lungs.
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