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Biomedical subjects

P M Logan

Publications and source records attributed to P M Logan.

At least 37 records · Page 2Linked to original sources

Soft tissue osteosarcoma with telangiectatic features: MR imaging findings in two cases.

Extraskeletal osteosarcomas are rare tumors, and the telangiectatic variety is the least common histological variety in this group. This report describes the clinical and MR imaging findings in two cases arising in the pretibial soft tissues. Both tumors demonstrated marked inhomogeneity with T2-weighted spin echo and STIR sequences. One of the tumors revealed numerous fluid levels within the lesion. A review of the MRI features of these tumors is provided. Osteosarcoma with telangiectatic features should be considered in the differential diagnosis of a soft tissue mass with fluid-fluid levels in patients 40 years of age or older.

Aged↗

Congenital thoracic masses: imaging features in the adult.

Congenital anomalies in the adult thorax are frequently asymptomatic and may remain undetected for many years. Whether they then become symptomatic or are discovered as an incidental finding on an imaging study obtained for unrelated reasons, thoracic anomalies may appear as masses or contour abnormalities that mimic other pathology, particularly neoplastic disease. The aim of this review is to discuss and illustrate a wide variety of congenital thoracic anomalies that can potentially present as a mass in the thorax. For ease of discussion, lesions are classified under numerous headings, including congenital lung anomalies caused by bronchopulmonary malformations and anomalies of pulmonary vasculature, vascular anomalies of the great vessels, diaphragmatic anomalies, and congenital masses of the chest wall. The appearance of these congenital lesions on chest radiographs and other imaging modalities such as CT, MRI, and angiography are illustrated, with emphasis on features that can distinguish these lesions from other intrathoracic masses.

Adult↗

Chondroid lipoma: MRI appearances with clinical and histologic correlation.

Chondroid lipoma is a recently described benign tumor of adipose origin which, pathologically, mimics myxoid liposarcoma and myxoid chondrosarcoma. This tumor typically presents as a well-defined mass in the superficial tissues of the extremities. In this report, we present the magnetic resonance imaging (MRI) appearances of a pathologically proven chondroid lipoma. To our knowledge, this is the first report of any imaging findings associated with this tumor.

Adipose Tissue↗

Post-radiation osteosarcoma of the scapula.

Osteosarcomas arising in irradiated tissues are uncommon but important complications of radiotherapy. Radiation-induced osteosarcomas generally occur 3-30 years after exposure and are most common after radiotherapy for cervical or breast carcinoma. These tumors are usually rapidly growing, extremely painful, and histologically high grade. In this paper, we report two cases of high-grade post-radiation osteosarcoma of the scapula. Despite being almost identical radiologically and pathologically, one case had a typical clinical presentation whereas the second case had two unusual features, being non-painful and arising in a field initially irradiated for bronchogenic carcinoma.

Aged↗

Diaphyseal telangiectatic osteosarcoma as a second tumor after bilateral retinoblastomas.

In this report, we describe the clinical, imaging, and pathologic findings in a case of diaphyseal telangiectatic osteosarcoma arising 23 years after successful treatment of bilateral retinoblastomas. To our knowledge, telangiectatic osteosarcoma occurring as a second tumor in this setting, outside the radiation treatment field, has not been previously reported. The association of the RB-1 gene defect with retinoblastomas and other tumors is discussed. Also, the computed tomography and magnetic resonance imaging findings in telangiectatic osteosarcoma are described and discussed.

Adult↗

Improving the detection of radiographically occult ankle fractures: positive predictive value of an ankle joint effusion.

OBJECTIVE: To assess the value of an ankle effusion on plain radiographs as a predictor of radiographically occult fracture after acute ankle trauma. PATIENTS: Consecutive patients with acute ankle trauma and radiographic evidence of an ankle joint effusion. Patients were excluded if ankle trauma was sustained more than 48 h previously or if a fracture was visible on initial photographs. METHODS: All subjects (n = 26) underwent computed tomography (CT) of the ankle in sagittal and coronal planes. Ankle effusion size was measured from initial lateral ankle radiographs. RESULTS: Twelve patients (46%) had radiographically occult fractures identified with CT. Fracture sites included: posterior or lateral malleoli (n = 4), calcaneus (n = 1), or talus (n = 7). Ankle effusion size was 11.2 mm in the group without fracture and 17.1 mm in the group with fracture (P < 0.0001). The positive predictive value of an effusion 15 mm or greater was 83%. CT detected significant soft-tissue injuries in four (15%) patients including peroneal retinaculum tear (n = 1), anterior talofibular ligament avulsion (n = 1), and tears of the peroneus longus (n = 1) and tibialis posterior (n = 1) tendons. CONCLUSIONS: The presence of a large ankle effusion of radiographs after acute ankle trauma suggests an underlying fracture. An ankle effusion of > or = 15 mm is a reasonable threshold to prompt additional imaging. Computed tomography provides good visualization of subtle bone injuries and may detect clinically imported soft-tissue injuries.

Adult↗

Bronchogenic carcinoma and coexistent bronchioloalveolar cell adenomas. Assessment of radiologic detection and follow-up in 28 patients.

PURPOSE: Bronchioloalveolar cell adenomas (BAAs) have been described in up to 10% of patients with bronchogenic carcinoma. Their prognostic significance is unknown. The purpose of this study was to determine the prognostic implications of finding BAAs coexisting in specimens resected for primary bronchogenic carcinoma and to determine how frequently BAAs can be detected radiologically. METHODS: Follow-up information for a mean of 30 months was obtained on 28 patients with a single primary bronchogenic carcinoma and one or more coexistent BAAs. Preoperative chest radiographs (n=27) and CT scans (n=24) were retrospectively reviewed to assess the number of patients in whom BAAs could be detected radiologically. RESULTS: There was no significant difference between percentage survival of patients with a primary bronchogenic carcinoma and coexistent BAAs when compared with the percentage predicted survival of these patients based on their primary bronchogenic carcinoma alone. BAAs could be detected retrospectively in 1 of 27 (4%) preoperative radiographs and 11 of 24 (46%) CT scans. CONCLUSIONS: On standard preoperative imaging for bronchogenic carcinoma, BAAs were retrospectively detected in more than one third of patients in whom they were detected pathologically. However, the presence of coexistent BAAs with bronchogenic carcinoma does not affect short- and medium-term prognosis.

Adenoma↗

Image-guided percutaneous biopsy of musculoskeletal tumors: an algorithm for selection of specific biopsy techniques.

OBJECTIVE: The purpose of this study was to design and use an algorithm for selection of the most appropriate biopsy technique. MATERIALS AND METHODS: An algorithm was designed to maximize the tissue sampling and diagnostic accuracy of musculoskeletal tumor biopsy. We used fine-needle aspiration to sample small ( < 3 cm) soft-tissue masses, an 18-gauge automated Biopty Gun to sample large ( > 3 cm) soft-tissue masses, a bone-cutting core biopsy needle to sample sclerotic bone tumors, and a combination technique to sample lytic bone tumors with an intact bony shell. We reviewed the results of 46 consecutive biopsies obtained with this algorithm. RESULTS: The overall diagnostic accuracy was 96%, with one inadequate biopsy and one inaccurate biopsy. The diagnostic accuracies within subgroups of tumor types were: primary malignant tumors (n = 15), 93%; primary benign tumors (n = 9), 100%; secondary malignant tumors (n = 11), 100%; secondary benign tumors (n = 8), 88%; and infections (n = 3), 100%. CONCLUSION: This algorithm allows selection of the biopsy procedure most likely to safely provide adequate and accurate biopsy samples.

Adolescent↗

Painful os cuboideum secundarium. Cross-sectional imaging findings.

The authors presented the computed tomography and magnetic resonance imaging appearances of a painful os cuboideum secundarium. To the authors' knowledge, this is the first report of the cross-sectional imaging appearance of this condition, and serves to underline the utility of computed tomography and magnetic resonance imaging in the investigation of foot pain.

Adult↗

Magnetic resonance imaging and histopathologic appearances of benign soft-tissue masses of the foot.

Magnetic resonance imaging (MRI) is now the modality of choice for the investigation of soft-tissue tumours, providing excellent anatomic detail and soft-tissue contrast. As the availability of MRI has increased, the number of requests for studies of the foot and ankle has similarly increased. The imaging department at the authors' institution, a tertiary care teaching hospital, has a large orthopedic and podiatric referral base, and as a consequence the authors have had the opportunity to study a large variety of benign soft-tissue tumours with MRI. In this pictorial essay they review the MRI and pathological appearances of the most common benign soft-tissue tumours that occur in the foot and ankle.

Adult↗

The snapping hip: clinical and imaging findings in transient subluxation of the iliopsoas tendon.

OBJECTIVE: To define the clinical, ultrasonographic and magnetic resonance imaging (MRI) findings in patients with painful snapping of the hip secondary to transient subluxation of the iliopsoas tendon. PATIENTS AND METHODS: Seven patients, ranging in age from 17 to 30 years, with a total of eight painful snapping hips were examined with static and dynamic ultrasonography and MRI during hip motion producing the painful snapping. The duration of symptoms, the level of disability and the response to therapy were recorded. RESULTS: Static ultrasonography showed thickening of the iliopsoas tendon (tendinitis) in two cases and a peritendinous fluid collection in two cases. In all cases dynamic ultrasonography of the iliopsoas tendon during hip motion showed distinct abnormal motion of the tendon corresponding temporally to the painful palpable and audible sensation. MRI showed normal intra-articular structures in all cases, tendinitis in two cases and iliopsoas bursitis in one case. Clinically, subluxation of the iliopsoas tendon is a chronic (mean duration of symptoms in this series, 23 months) disabling condition that may be relieved by surgical tendon release. CONCLUSIONS: Dynamic ultrasonography is useful for detecting transient subluxation of the iliopsoas tendon in patients with a painful snapping hip. MRI is useful for excluding intra-articular abnormalities in patients with this condition.

Adolescent↗