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Biomedical subjects

P M Leary

Publications and source records attributed to P M Leary.

16 recordsLinked to original sources
PubMed1979

Childhood convulsions.

An outline is given of the incidence and aetiology of childhood convulsions. Aspects of diagnosis and drug therapy are discussed.

Adolescent↗
PubMed1979

The effect of remedial teaching on children with learning disabilities.

A study of questionnaires completed by the parents and class teachers of 70 children with learning diabilities revealed evidence of considerable parental satisfaction with scholastic progress and improved behaviour. These advances were attended by a significant reduction in domestic tension and concern about the children's future. However, teacher ratings indicate that despite prolonged remedial teaching more than half of the group remained at a scholastic level below the average class performance.

Adolescent↗
PubMed1979

Changes in the electro-encephalogram related to the menstrual cycle.

A comparison has been made between the electro-encephalograms (EEG) recorded in the premenstrual phase and those recorded at mid-cycle in 25 healthy young women. In only 5 could no difference be discerned visually between the two records obtained from each subject. Eight premenstrual records showed a significant increase in mean alpha frequency and 17 showed an increase in mean alpha amplitude. Theta activity and mild paroxysms were twice as common in premenstrual records, as was an abnormal response to hyperventilation. These findings may correlate with subjective mood changes commonly experienced in the premenstrual phase and in the well-recognized tendency of certain epileptic women to have seizures only at the time of their menses. It is suggested that when reporting on the EEGs of female subjects, cognizance should be taken of the stage reached in the menstrual cycle at the time of recording.

Adult↗
PubMed1979

Clinical experience with methylphenidate.

The indications for the use of methylphenidate in 250 children are reviewed, and the effect of the drug is examined. Concentration was improved or hyperactive behaviour diminished in 89% of the children with normal intelligence and with no gross physical defect, in 72% of the children with cerebral palsy, and 68% of the children with subnormal intelligence. In children with emotional disturbance, response to methylphenidate was seldom satisfactory. Significant side-effects occurred infrequently and only 2 children lost weight during the period of medication.

Adolescent↗
PubMed1978

The electro-encephalogram in childhood.

The electro-encephalogram (EEG) is a useful adjunct when clinical history and physical examination suggest the diagnosis of epilepsy, whether idiopathic, focal or petit mal. It may be helpful in separating the child with simple convulsions due to fever from the child whose epileptic dysrhythmia first finds outward expression while he is feverish. The real nature of disordered behaviour may be demonstrated by the EEG which shows specific evidence of temporal lobe abnormality. In many infective and metabolic disorders of childhood, the EEG has little if any diagnostic specificity, and there is real danger that a variety of entities, such as abdominal pain, aggressive behaviour or minimal brain dysfunction, may be incorrectly attributed to cerebral dysrhythmia on the basis of incidental EEG changes.

Attention Deficit Disorder with Hyperactivity↗
PubMed1977

Experience with the EMIT method of determining anticonvulsant levels in serum.

Clinical and laboratory experience with the EMIT immunoassay method for the determination of serum phenobarbitone levels is reported. A modification of the published laboratory method permitting manual operation in a general clinical chemistry laboratory was used. In 42 of the 75 children monitored, the serum levels of phenobarbitone indicated a change of the prescribed dosage.

Adolescent↗
PubMed1976

Minimal brain dysfunction.

The syndrome of minimal brain dysfunction is found in at least 5% of South African schoolchildren. The aetiology and pathology of this entity are uncertain. Presenting features include hyperactive behaviour, problems of fine motor co-ordination, learning disabilities and certain 'soft' neurological signs. Skilled remedial teaching is the mainstay of successful management.

Attention Deficit Disorder with Hyperactivity↗
PubMed1976

A Poisons Reference Centre for children.

A statistical analysis of poisoning cases treated at the Red Cross Children's Hospital is presented. The organisation and functioning of the Poisons Reference Centre is described and an analysis made of the poison ingestions reported to the Centre.

Child↗
PubMed1975

Down's syndrome with additional XYY aneuploidy.

A further case of Down's syndrome with additional XYY aneuploidy is reported. The child has been followed for 5 years. It has not been possible to recognise any phenotypical feature which distinguishes the patient from others with Down's syndrome.

Aneuploidy↗