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Biomedical subjects

P Loup

Publications and source records attributed to P Loup.

At least 37 records · Page 2Linked to original sources

[Postoperative gastritis caused by reflux. Apropos of 16 cases].

We observed 16 patients suffering from postoperative gastritis: 8 after a truncal vagotomy with pyloroplasty, 6 after a Billroth II type gastrectomy, 1 after a truncal vagotomy with a Billroth I type antrectomy, 1 after correction of a hiatal hernia with pyloroplasty. Symptoms appeared from 1 month to 16 years after surgery. They consisted in epigastric pain, nausea, vomiting, weight loss. The diagnosis is established essentially on the clinical picture and the endoscopy, which shows the presence of bile in the stomach and hyperemia of the mucosa. Microscopic lesions are constant, but there is no histologic specificity. 12 of 16 patients were operated on (Roux-enY loop). The reflux was suppressed in each case. Results of the operation were excellent or good in 10 patients, fair in one and unsatisfactory in one.

Adult↗

[Value of Warren's distal spleno-renal shunt in the treatment of esophageal varicosities].

Analysis of 22 patients who underwent distal spleno-renal shunt shows that postoperative mortality is low, thrombosis of the shunt rare, and the risk of encephalopathy minimal. Decompression of esophageal varicositis is effective, but probably less marked and slower than after porta-caval shunt. Accordingly, distal spleno-renal shunt is not recommended as an emergency procedure.

Adult↗

Efficacy and risks of the distal splenorenal shunt in the treatment of bleeding esophageal varices.

Analysis of twenty-two patients who underwent distal splenorenal anastomosis shows that the operative mortality and morbidity are low if the indications for the procedure are strictly adhered to. The decompression of the esophageal varicosities is effective, even in the presence of persistent varicosities. This decompression is probably less important and perhaps slower than after portacaval shunting, so we now do not recommend distal splenorenal shunting as an emergency operation. Thrombosis of the shunt is rare and related especially to local anatomic conditions and operative technic. Shunt thrombosis is an early complication that we observed on two occasions manifested by recurrence of hemorrhage. There does not appear to be an appreciable difference between the terminoterminal and terminolateral distal splenorenal anastomoses. The effect of ligation of the splenic artery in the hypersplenism is doubtful. The frequency of postanastomotic encephalopathy is minimal with this type of shunt. Liver function tests were little changed during the period of postoperative observation, but our results do not permit us to conclude that the distal spleno-renal anastomosis less unfavorably affects liver function than do classic shunts.

Adult↗

[Splenic repercussions after Warren's distal spleno -renal shunt].

Volume and function of the spleen were checked in 14 patients 6 months to 7.5 years (average: 2.5 years) after Warren distal spleno-renal shunt. In addition to the shunt, the splenic artery was ligated proximally in 5 cases. Splenomegaly decreased in half of the patients. In 8 out of the 13 patients with preoperative hypersplenism, the latter improved or disappeared after operation. Increased splenomegaly or hypersplenism was never found postoperatively. Splenic effects of the distal spleno-renal shunt are related to the improvement of the venous stasis. Efficiency of the splenic artery ligation is so doubtful that we do not recommend such a procedure.

Adult↗

[Elective decompression of esophageal varices using Warren's distal splenorenal bypass].

Distal spleno-renal anastomosis is worth consideration in the treatment of certain forms of portal hypertension, especially when there is a satisfactory portal blood flow. Apart from the low operative mortality and morbidity its main advantages are the preservation of portal hepatic blood flow, the reduction or suppression of which may have a deleterious effect on the liver, and also avoid or reduce to a minimum the risk of portal systemic encephalopathy, while producing effective decompression of the oesophageal varices. This operation is contra-indicated in presence of a greatly reduced or inversed portal blood flow, and also in cases of ascites or marked stasis of the splanchnic or retroperitoneal lymphatic network.

Adult↗