[Orbital tumors following resection of an optic nerve glioma. Apropos of 2 cases].
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Biomedical subjects
Publications and source records attributed to P Lesure.
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PURPOSE: To assess the safety and efficacy of a second generation, anterior chamber phakic intraocular lens (Baikoff Model ZB5M) in patients with high myopia. METHODS: One hundred and twenty-one patients (134 eyes) with myopia of -7.00 to -18.80 D were implanted with the ZB5M lens and followed for 18 to 52 months; the number of eyes evaluated was: 6 months (104 eyes), 1 year (91 eyes), 18 months (78 eyes), 2 years (68 eyes), and 3 years (35 eyes). RESULTS: Postoperative spherical equivalent refraction averaged -1.00 D and the error in refractive correction (achieved minus intended) averaged -0.40 D during the first 2 years, increasing -to -1.30 D refraction and -0.60 D error in refractive correction at 3 years. At 2 years, approximately 40% of eyes had a spherical equivalent refraction within +/-0.50 D, and 65% within +/-1.00 D. The uncorrected distance visual acuity was 0.048 at baseline and 0.5 at 3 years; near visual acuity was 0.21 at baseline and approximately 0.7 over the 3 years of follow-up. Spectacle-corrected distance visual acuity at baseline was 0.54; it improved to 0.7. Near visual acuity was 0.65 at baseline and it improved to approximately 0.75. Endothelial cell counts in the central and peripheral cornea were reduced by an average 3.3% at 6 months, declining an additional 1% to 2% over the remaining follow-up period. Regression analyses indicated that most of the endothelial cell loss was due to surgery. Additional complications included halos/glare in 37 of 133 eyes (27.8%) and iris retraction with pupillary ovalization in 30 of 133 eyes (22.6%). The intraocular lens was exchanged in four of 133 eyes (3.0%) and removed in three of 133 eyes (2.3%), the latter because of halos (one eye) and a flat anterior chamber with severe inflammation (two eyes). CONCLUSIONS: Implantation of the Baikoff ZB5M lens in the anterior chamber of phakic eyes significantly reduced high myopia and produced a stable refractive outcome over the 3 years, accompanied by marked improvement in uncorrected distance visual acuity and minimal, non-progressive damage to the corneal endothelium. Frequent complications included pupillary ovalization and halos/glare. Improvements in accuracy of IOL power calculations are needed.
The authors describe a new anaesthetic protocol for laboratory rabbits. The surgery consists in an extracapsular lens extraction with intraocular lens implantation in the bag. The anaesthetic protocol requires: an intravenous induction with ketamine (20.2 mg/kg +/- 5) and midazolam (0.65 mg/kg +/- 0.3) and after an oral endotracheal intubation with a simple method, and at last maintaining halothane anaesthesia with a concentration between 3 and 4%. 45 anaesthesia were performed: the average time of the anaesthesia was 77 min +/- 16. No rabbit died because of this anaesthesia. The anaesthesia was a success for the surgeon who could operate in the best working conditions.
Sequellae of Graves' orbitopathy often need a functional or cosmetic correction. The different procedures are reviewed with special commentary (orbital decompression, surgery of oculomotor disturbances, lid retractions and orbital fat protrusion). A modified procedure for levator lengthening is described.
Aetiologic conditions for enlargement of extra ocular muscles are graves' orbitopathy, acute or subacute myositis as a subgroup of inflammatory orbital pseudotumor, and sometimes lymphoid or metastatic tumor. The distinction of these aetiologies can be made on clinical versus CT Scan or IRM grounds with two different patterns of oculomotor disfunction. Restrictive extensibility, which found expression in the antagonist field, is typical of grave's myopathy, sequelae of subacute myositis or acute myositis of the superior oblique. Deficiency of the enlarged muscle's contractibility is typical of a recent and transient myositis involving a rectus muscle or of a rare tumor of an extraocular muscle.