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Biomedical subjects

P Lemoine

Publications and source records attributed to P Lemoine.

At least 73 records · Page 4Linked to original sources
PubMed1983

[Not Available].

Explore the source record for details and available documents.

France↗
PubMed1983

[The Permanent Safety and Health Commission for Coal Mines and other Extraction Industries].

After having congratulated the C.C.R. on the 25th anniversary of its foundation, the secretary of the Safety and Health Commission for the Mining and Other Extractive Industries, which also celebrates its silver jubilee, briefly exposes its history, composition and modus operandi. In essence the duties of the Safety and Health Commission are to propose measures to the governments to increase safety, firstly in mines and subsequently in all the extractive industries. Its working is based on eleven working parties where the best safety experts of the European extractive industries collaborate. The Commission is also empowered to make proposals for research, to promote safety campaigns and to organize information sessions for the industrial circles concerned. The positive appreciation and the active collaboration of these circles help the Safety and Health Commission to fulfill its task.

Accident Prevention↗
PubMed1983

[Ethics of research in psychiatry. Comparison of France and the United States].

This article presents a comparison of research ethics in psychopharmacology in France and the United States. The authors present some elements of definition, etymology and of history. In addition, they study how this very specific research is actually done. Many questions are discussed, including the right of the patient, and the problem of normal volunteers. Other aspects are more technical i.e. remuneration, protocol, and the product. Finally the role of the ethics committees is investigated. These committees comprise the third component of the trial that consists of the research and the subject.

Clinical Trials as Topic↗
PubMed1981

Double-blind trial of amineptine and clomipramine in the treatment of depression.

A double-blind trial was carried out in 62 depressed patients to compare the clinical efficacy and acceptability of amineptine and clomipramine. Patients were allocated at random to one or other of two treatment groups and received daily doses of amineptine ranging from 100 to 300 mg (mean 180 mg) or of clomipramine ranging from 50 to 150 mg (mean 84 mg) over a period of 6 weeks. Global assessment of response to treatment and Hamilton Rating Scale scores, assessed before and after 1,3 and 6 weeks of treatment, indicated that the two drugs appeared to be equally effective and no differences between them could be demonstrated in the analysis of the individual items or grouped items of the scale used. Measurements of ocular tone showed that there was significantly less risk of amineptine producing an increase in tone, and blood pressure and electrocardiographic investigations also underlined the greater cardiovascular tolerance of amineptine. Five (16%) of the 32 patients in the clomipramine group were withdrawn from the study because of adverse effects.

Adolescent↗
PubMedDate not supplied

Comorbidity of mental and insomnia disorders in the general population.

The co-occurrence of insomnia and mental disorders constitutes the most prevalent diagnosis pattern found in sleep disorder clinics. Yet, there remains a paucity of epidemiological information regarding comorbidity of mental disorders and sleep disorder symptomatology in the general population. The present study showed results based on a large representative French cohort (n = 5,622; 80.7% of the contacted stratified sample). A total of 997 (17.7%) individuals with insomnia complaints were identified and divided into six diagnostic categories: (1) Insomnia related to a Depressive Disorder; (2) Insomnia related to an Anxiety Disorder; (3) Depressive Disorder accompanied by insomnia symptomatology; (4) Anxiety Disorder accompanied by insomnia symptomatology; (5) Primary Insomnia; and (6) isolated insomnia symptomatology. Telephone interviews were conducted using the Sleep-Eval System. Subjects with insomnia related to a Mental Disorder have a longer history of insomnia complaints and are usually younger than those with Depressive or Anxiety Disorders accompanied by insomnia symptoms. Subjects with Insomnia related to a Depressive Disorder experienced more repercussions than any other group. A surprisingly high percentage of individuals with depressive symptomatology had sought independent medical treatment specifically for their sleep problems, which raises the unsettling possibility that many cases of depression go undetected by the general medical community. The distinct predictability of commonly undiagnosed depression leading to chronic depression speaks directly to the imperative that physicians receive additional training in this area of community mental health.

Adolescent↗