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Biomedical subjects

P Lefebvre

Publications and source records attributed to P Lefebvre.

334 records · Page 19Linked to original sources

[Germ cell tumour and pseudohermaphroditism. Histological and cytogenetic study (author's transl)].

The case report is that of a 15 years old boy presenting with unilateral undescended testis and hypospadias. Surgical exploration disclosed an absence of regression of the Müllerian system and an intra-abdominal gonad replaced by a seminoma. There are arguments to suspect that the seminoma arose from a gonadoblastoma controlateral testis biopsy disclosed a germ cell abnormality consistent with an in situ neoplastic transformation. It is emphasized that all forms of cryptorchidism must be explored surgically and that apparently normal gonads left in place in cases of unilateral gonadic dysgenesis, must be attended with extreme care.

Adolescent↗

[A seasonal neurologic disease: paralysis following tick-bites (author's transl)].

Seasonal inflammatory neurologic disorders following tick-bites have been reported more and more often during the last few years. They usually consist in a peripheral neurologic syndrome. However, involvement of the central nervous system is not uncommon. Two new cases seen at the Val-de-Grâce Hospital are reported here. The author reviews the circumstances in which the disease occurs and it's clinical features. The course is variable and may result in serious sequelae. Pathogenesis remains unknown. Viral, toxinic, and immuno-allergic factors have been incriminated. Practitioners should consider this diagnosis, during the summertime, especially in high-risk subjects (campers, agricultural workers, troops during field exercise).

Adolescent↗