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P Lefebvre

Publications and source records attributed to P Lefebvre.

At least 253 records · Page 14Linked to original sources
PubMed1973

Glucose naturally labeled with carbon-13: use for metabolic studies in man.

The ratio of carbon-13 to carbon-12 is much higher in most commerical preparations of glucose used for oral glucose tolerance tests than it is in carbon dioxide in expired air. This recent discovery provided a novel and potentially significant means of studying glucose metabolism. The changes in the ratio of carbon-13 to carbon-12 in carbon dioxide expired after oral glucose administration were determined by mass spectrometry. In six healthy male volunteers, the administration of glucose resulted in a marked, reproducible rise in the isotopic ratio in expired carbon dioxide; the ratio reached its maximum at 4 hours and then declined progressively.

Adult↗