Search PubMedSearch

Biomedical subjects

P Lancaster

Publications and source records attributed to P Lancaster.

11 recordsLinked to original sources

Cough intensity in patients with a vocal cord palsy.

This study assesses the effect a paralysed cord has on the intensity of coughing. The air flow pattern during coughing of 10 patients with a vocal cord palsy was compared with a control group, using a computerized pneumotachograph system. There was no significant difference in the value of the peak air flow but the time taken to reach the maximum value was prolonged in the vocal cord palsy group. This non-invasive test may aid diagnosis of vocal cord palsies but the laterality of the lesion cannot be predicted from the airflow pattern alone.

Adult

The effect of frequency on combined glottography.

This study investigates the relationship between frequency and the open quotient (OQ) and speed quotient (SQ) values of combined glottography. Simultaneous electroglottography and photoglottography were performed on 20 healthy male subjects. Regression analysis showed that neither OQ nor SQ was dependent upon frequency. The technique is therefore still valid despite the inability to control this variable.

Adult

The effect of intensity on combined glottography.

This study investigates the relationship between intensity and the open quotient (OQ) and speed quotient (SQ) values of combined glottography. Simultaneous electroglottography and photoglottography were performed on 20 healthy male subjects at intensities of 55 and 65 dB. Paired t-test statistical analysis showed that the open quotient varies inversely and the speed quotient directly with the intensity. When reporting findings it is therefore necessary to state the intensity at which the results were obtained.

Adult

Cough intensity in the laryngectomee.

The exact role or even the necessity for a functioning larynx in the production of an efficient cough is unknown. This study compares the cough intensity of 10 laryngectomees with a control group of 10 individuals with a larynx. There is no significant difference in the peak flow but the time taken to reach the peak flow is prolonged in the laryngectomees. The supramaximal expiratory flow is thus absent. The larynx is not essential for coughing although the different pattern may be less efficient. This simple test may have diagnostic value in assessing the larynx.

Aged

An outpatient clinic system for glottographic measurement of vocal fold vibration.

It has recently been suggested that combined electroglottography and photoglottography may aid diagnosis and assessment of treatment of laryngeal pathology. The ability to record and analyse such traces was previously restricted to voice research laboratories. A simple, less expensive, system for use in the outpatient clinic is described. A preliminary study on 10 normal subjects produced results comparable to that of voice research laboratories. The clinical potential is discussed. This may represent a valued addition to the armamentarium of the clinician.

Electrophysiology

The wider perinatal significance of the Australian in vitro fertilization data collection program.

The most recent report (1986) from the Australian Register of In Vitro Fertilization pregnancies comprises 2242 in vitro fertilization (IVF) pregnancies and 261 gamete intrafallopian transfer (GIFT) pregnancies. A review of this data base indicated that this population had a relatively high incidence of both obstetric and perinatal morbidity and perinatal mortality. About 58% of the IVF pregnancies resulted in live births and 36.4% of the infants weighted less than 2500 gm at birth. These high rates could be partially accounted for by maternal prepregnancy risk factors, such as age, and by risk factors associated with the infertility management, such as multiple pregnancy (22% of all pregnancies more than 20 weeks), which accounted for approximately 50% of the preterm births (less than 37 weeks). Singleton pregnancies also had a higher incidence of preterm birth (17.8% at gestational age 24 to 36 weeks), low-birthweight babies (15.9% less than 2500 g) and perinatal mortality rates (35.4% per 1000 live births) than the Australian population at large. This warrants these patients being regarded as high risk. It is reassuring that the incidence of major malformations in IVF births (2.2%) is similar to that in the general population (1.4%).

Australia

Smoking and pregnancy.

Smoking is associated with decreased fertility in both males and females, an increased abortion rate, lowered birth weight, an increased still birth rate and probably an increased neonatal death rate. There is also a reduced incidence of maternal hypertension (although the babies are at even greater risk), an increased incidence of ante-partum haemorrhage, impaired brain development and possible teratogenic effects. These effects can be reversed if the mother gives up smoking in pregnancy.

Animals