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Biomedical subjects

P L Sheitel

Publications and source records attributed to P L Sheitel.

5 recordsLinked to original sources
PubMed1991

Treatment of painful diabetic neuropathy with capsaicin 0.075%.

An 8-week, double-blind, vehicle-controlled study was conducted to determine the effectiveness of topical capsaicin 0.075% cream in relieving pain associated with diabetic neuropathy. Patients were selected who experienced moderate to very severe pain, which interfered with sleep or activities on a daily basis, and who were unresponsive or intolerant to conventional therapy. The results after 8 weeks showed a statistically significant difference in favor of the capsaicin-treated patients, with 90% of these patients improved. The results of this study indicate that topical capsaicin 0.075% cream is safe and effective in managing painful diabetic neuropathy.

Administration, Topical↗
PubMedDate not supplied

Use of Cryo/Cuff for the control of postoperative pain and edema.

Presented as a new modality, the Cryo/Cuff system incorporates a combination of hydrostatic pressure and cold to reduce post-traumatic pain and edema. It was hypothesized that this combination would also significantly reduce postoperative pain and edema. A sample population of 25 participants who were scheduled to have bilateral foot surgery was selected. Baseline circumference was determined preoperatively. Instruction and demonstration of the apparatus was given to the participants; an ice cap was used on the left foot as a control. The system is designed as a boot to be worn over the foot and ankle. Attached to the boot by a tube is a reservoir containing water and ice. Elevation of the reservoir may provide up to 40 mm. of mercury pressure. Study data gathered incorporated both evaluation by calculation of standard deviation above or below circumference mean as well as two subjective modes of patient assessment. Eighty percent of study participants experienced a reduction of pain and swelling at the first and subsequent postoperative visits. The Cryo/Cuff system appears to be an effective modality in the facilitation of the postoperative recovery process.

Adolescent↗