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Biomedical subjects

P K Sikdar

Publications and source records attributed to P K Sikdar.

6 recordsLinked to original sources

Serology and immunoglobulin profile in rheumatoid arthritis.

One hundred and twenty cases of clinically diagnosed rheumatoid arthritis, 80 non-rheumatoid cases suffering from various other diseases and 40 healthy individuals were investigated for the presence of rheumatoid factor, quantitation of serum immunoglobulin, demonstration of ANA and LE cell phenomenon. Microlatex agglutination test of serum for rheumatoid factor showed 56.6% positivity in rheumatoid group and 3.7% positivity in non-rheumatoid group. All three serum immunoglobulins (IgG, IgM, IgA) were raised in serum in significant titre in cases of rheumatoid arthritis, whereas only IgA lever was elevated in the group of non-rheumatoid diseases. ANA and LE cell phenomenon were observed in 11.7% and 4.4% cases of rheumatoid arthritis who had severe underlying disease. In non-rheumatoid group, only one of 6 cases of systemic lupus erythematosus showed rheumatoid factor and that too in an insignificant titre (less than 1:20). Synovium and synovial fluid contained plenty of plasma cells and lymphocytes. It has been observed that RF appears first in synovial fluid and it may take several months to a year to attain detectable level in serum.

Adolescent↗

Spatial aggregation in gravity models: 2. One-dimensional population density models.

"This paper, the second of four, is concerned with applying a methodology for analysing the spatial aggregation problem in gravity models outlined in the first paper. The methodology is based on a consistent framework for linking measures of pattern in interaction data to the derivation and estimation of related interaction models using spatial information. In this quest, a link is forged between information in data and the parameters of an associated model.... This relationship can be formalised for the case of the continuous one-dimensional interaction model such as the population density model, and this paper is concerned with demonstrating such an application to aggregations of zones in the Reading [England] region."

Demography↗

On population growth of cities in a region: a stochastic nonlinear model.

"A stochastic migration model describing the population dynamics in a region is investigated. The model is described by a pair of coupled differential equations with state-dependent stochasticity. Explicit expressions for the time evolution of the moments for the population sizes of cities are obtained from the Fokker-Planck equation. The Stratonovich calculus is employed in the analysis."

Demography↗

Spatial aggregation in gravity models: 4. Generalisations and large-scale applications.

"This paper is concerned with applying and extending a methodology for analysing spatial aggregation in gravity models developed in three earlier papers to a larger scale and hence more realistic example of spatial interaction than has been treated so far." Seven models are generated and applied to four levels of aggregation of the spatial interaction pattern in Edmonton, Alberta.

Americas↗