Search PubMed⌕ Search

Biomedical subjects

P K Devi

Publications and source records attributed to P K Devi.

At least 73 records · Page 4Linked to original sources
PubMed1975

Effect of prostaglandin F2 alpha and hypertonic saline on the placental function during midtrimester abortion.

Changes in placental function during the induction of midtrimester abortion by prostaglandin F2 alpha and hypertonic saline were investigated. Serial estimations of human placental lactogen (HPL) and cystine aminopeptidase (CAP) were carried out in 17 subjects. There was a significant (P smaller than 0.01) reduction in the plasma CAP and HPL levels 4 hours after PGF2 alpha administration. In the case of hypertonic saline abortions only HPL levels showed a reduction at 8 and 12 hours after induction.

Abortion, Induced↗
PubMed1972

Metabolic effects of contraceptive steroids. I. Observations of blood lipids.

Semilongitudinal observations on fasting blood sugar, total lipids, cholesterol, phospholipids, triglycerides, nonesterified fatty acids (NEFA), and lipoproteins were carried out on 116 women taking combination type oral contraceptives for 3-42 cycles. The changes observed differed with each constituent. Total lipids showed significant increase throughout the period of observation. Cholesterol and phospholipds showed significant increases after about 12 cycles of administration whereas triglycerides showed an increase after 6 cycles of medication. NEFA showed significant decrease in the 1st-3rd cycles. The alpha and beta lipoprotein ratios showed significant changes after 13-24 cycles of treatment. The general trend of change observed is similar to that reported during pregnancy.

Biology↗
PubMed1972

Metabolic effects of contraceptive steroids. III. Intravenous glucose tolerance--short term observations.

Intravenous glucose tolerance tests were carried out in women taking 2 types of estrogen/progestogen combination oral contraceptives. Each subject had the test done on days 18-21 in a control cycle before the medication was begun and 3 consecutive cycles during administration of the drug. Fasting blood glucose levels and K values showed no significant changes with a combination of megestrol acetate (4 mg) with 0.05 mg of ethinyl estradiol. A significant decline in glucose tolerance was observed by the change in K values during all 3 cycles of medication with a combination of 2.5 mg lynestrenol and 0.075 mg mestranol. Tests repeated 2 months after stoppage of the medication in 5 subjects showed that blood sugar levels and K values had returned to pretreatment levels.

Age Factors↗