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Biomedical subjects

P K Carpenter

Publications and source records attributed to P K Carpenter.

14 recordsLinked to original sources
PubMed2000

The Bath Idiot and Imbecile Institution.

The Bath Institution for Idiot Children and those of Weak Intellect was founded in 1846 by Miss Charlotte White, and opened in April 1846 in two rooms with a resident matron and three pupils. It was unique amongst the Idiot Asylums in being managed by women. In time it became similar to any small private idiot home but the Commissioners in Lunacy forced its reform, without registering it as an idiot asylum. It was taken over by the Bath Municipal Charity Trustees. It eventually became an endowed school, licensed by the Board of Control. This paper describes its history and its eventual control by the Lunacy Commission.

Charities↗
PubMed1997

The pauper insane of Leicester in 1844.

In 1844 the Poor Law Commissioners followed up a dispute with the Guardians of Leicester Union regarding the care of Pauper Lunatics by appointing Dr Samuel Hitch, an Assistant Poor Law Commissioner, to survey the treatment and condition of the pauper insane in Leicester and Birmingham Workhouses. At Leicester he exceeded his brief and surveyed the 13 insane on outdoor relief, 29 in the workhouse and 23 in the asylum. As such it is one of the earliest surveys of an area. This paper describes the dispute, the report and considers its aftermath.

Almshouses↗
PubMed1994

Prader-Willi syndrome in old age.

This case report describes a person with Prader-Willi syndrome who recently died, aged 71 years. It is suggested that her longevity was helped by being female, with a moderate degree of mental handicap and a degree of weight control which reduced the problems of diabetes and hypertension.

Aged↗
PubMed1990

Association of acrocyanosis with Asperger's syndrome.

The authors present three men with both acrocyanosis and Asperger's syndrome. Though the general incidence of acrocyanosis is unknown, they suggest that it is probably more common in autistic disorders and may be caused by hyperserotonaemia.

Adolescent↗
PubMed1990

Confirmation of metastatic prostatic carcinoma to lung by immunohistochemistry.

In recent years, immunoperoxidase staining of fine needle aspirates has been proposed. This study examines the use of immunoperoxidase staining of prostatic acid phosphatase and prostatic specific antigen in two cases where differentiation of prostatic carcinoma from other carcinomas manifesting as metastatic lesions is essential. The histologic differentiation of primary and metastatic disease, which has significant therapeutic and prognostic implications, has been enhanced by the use of immunoperoxidase staining. The presented cases demonstrate the ease with which immunoperoxidase staining can be done in a community hospital.

Adenocarcinoma↗
PubMed1989

Epilepsy and arson.

A man temporarily developed an organic personality change, psychosis and epilepsy after a frontal lobe operation for a subarachnoid haemorrhage. While affected, he set fire to his house. The arson is thought to have been a direct result of a seizure. The case and its legal management are discussed.

Adult↗
PubMed1981

Trazodone--a new assay procedure and some pharmacokinetic parameters.

1 A simple and specific procedure is described for the determination of the new anti-depressant trazodone in human plasma utilising reverse-phase HPLC which is sensitive to 20 ng ml-1. 2 Following oral administration of single 50 mg doses of two formulations of trazodone on separate occasions to healthy fasted volunteers, the peak plasma concentration, time to peak concentration, area under the curve, elimination rate constant and half-life were determined. 3 The two formulations are closely similar and they are considered to have comparable bioavailability.

Biological Availability↗
PubMedDate not supplied

Descriptions of schizophrenia in the psychiatry of Georgian Britain: John Haslam and James Tilly Matthews.

John Haslam's description of James Tilly Matthews is the earliest clear description of schizophrenia in British psychiatric writing. Matthew's life and symptomatology are described. The reasons why there are few unambiguous contemporary accounts of schizophrenia are explored. Schizophrenia was probably first described in Britain during the Georgian period because of the growth of the public lunatic asylum, combined with an improvement in the style of case description.

History, 18th Century↗