[Experimental study of digestive hemorrhages caused by drugs].
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Biomedical subjects
Publications and source records attributed to P Jobard.
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The authors report a new case of generalized congenital fibromatosis in a young white girl who presented at birth a sub-cutaneous frontal localization with osteolytic lesions. At three and a half months of age, a complete auriculo-ventricular block was discovered secondary to a myocardial localization and she died of acute respiratory failure without showing early anormal pulmonary radiological lesions. In reviewing ten cases of this generalized congenital form of the osteolytic lesions encountered, and stress the fact that the discrete radiological pulmonary signs that condition the prognosis. The then discuss the utility of distinguishing diffus and generalized forms of congenital fibromatosis.
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We report two cases of acquired cystic disease of the kidneys in patients on long-term hemodialysis. The gross appearance of these polycystic kidneys can be distinguished from the congenital adult type by their normal size and weight and by the small range of their cysts. We found some similarity between these numerous cysts and the simple retention cysts. This polycystic disease could concern about 30 % of the whole patients on long-term hemodialysis ; the mechanisms of its development are unknown. Clinically, this lesion is mostly asymptomatic but could sometimes be discovered by intra or perirenal haemorrhage.
This report describes a malignant tumor of soft tissue which combined granular cells with an histologic pattern of malignant fibrous histiocytoma. Immunohistological and ultrastructural studies were performed. Neo-plastic cells were devoid of S-100 Protein but contained lysozyme. Ultrastructural findings showed granular cells containing numerous lysosomes and non-granular cells exhibiting fibroblastic and histiocytic differentiations. This lesion prompts us to consider either a malignant granular cell tumor or a malignant fibrous histiocytoma.
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