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Biomedical subjects

P J Zuidema

Publications and source records attributed to P J Zuidema.

At least 19 recordsLinked to original sources
PubMed1996

[A Chinese patient with pernicious anemia; a medical experience from the Indonesian period].

On May 19th 1952 a 64-year-old Chinese man was admitted to a hospital at Yogyakarta (Indonesia) on account of a sawing noise in both ears and some soreness of the tongue. He had macrocytic anemia (haemoglobin: 3.7 mmol/l) and the tongue showed some smooth patches. A presumptive diagnosis of pernicious anaemia was confirmed by gastric analysis which revealed a histamine fast achlorhydria. On treatment with vitamin B12 the noise in the ears rapidly disappeared and there was a characteristic rise in reticulocytes and haemoglobin content. After 3 years the patient died of inoperable gastric carcinoma. There probably was a hereditary component as in a 54-year-old cousin, who also suffered (and died) from gastric carcinoma, gastric analysis showed a histamine fast achlorhydria. The patient is the first case of pernicious anaemia described in a Chinese resident of Indonesia. A survey of the literature revealed that until now pernicious anaemia has been recorded in 31 Chinese patients, in chronological order from the following countries: U.S (1945), Indonesia (1954), Singapore (1967), Hong-Kong (1969) and China (1990). In the autochthonous Chinese population no case has yet been reported.

Achlorhydria↗
PubMed1995

[Supraventricular tachycardia in a pregnant woman with tertiary malaria; a medical experience from the Indonesian period].

A 22-year-old Indonesian woman became ill with fever and chills in the 7th month of her fourth pregnancy. Two days later she complained of palpitations. At admission again two days later, the temperature was 40 degrees C. The heart rate was 175/min. A blood slide contained trophozoites of Plasmodium vivax. The ECG showed an atrioventricular junctional tachycardia. Treatment consisted of 2 intramuscular injections of 0.5 g quinine hydrochloride administered with an interval of 4 hours. The following morning the temperature was normal and the heart rate had fallen to 100/min. The ECG showed a sinus rhythm. Further therapy consisted of 1.2 g quinine sulphate daily. This case does not support the view that pregnancy may predispose to a paroxysm of tachycardia. It is noteworthy that in this patient 1 gram of quinine hydrochloride not only controlled a malaria attack but also terminated a paroxysm of tachycardia.

Adult↗
PubMed1981

The Katayama syndrome; an outbreak in Dutch tourists to the Omo National Park, Ethiopia.

The Katayama syndrome, the early stage of schistosomal disease, occurs 3 to 6 weeks after infection. The main symptoms are fever, urticaria, oedema and general malaise. Eosinophilia is a constant finding. The syndrome developed in a group of Dutch tourists after a visit in early November 1975 to the Omo National Park, southwest Ethiopia. Eight out of 10 infected persons became clinically ill. The incubation period varied from 4 to 41 days with a mean of 26 days. Pyrexia occurred in 6 patients, usually associated with headache and muscle pains; only to one patient the fever lasted for more than two weeks. Fever followed by oedema was present in one patient. Two patients were afebrile, one suffered from urticaria, the other from general malaise. Two visitors remained asymptomatic, but the results of serological tests showed that they were also infected. The liver function was disturbed in one patient during the febrile period and further deteriorated during treatment with niridazole. S. mansoni eggs were detected in small numbers in two patients, 6 months and 19 months after infection. Obviously the tourists harboured few adult worms. They probably had been infected by few cercariae; the possibility that they were infected by cercariae of a S. mansoni strain not well adapted to man was considered.

Adult↗
PubMed1979

[Shigellosis].

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Adolescent↗