Biomedical subjects
Publications and source records attributed to P J Tsaknis.
Examination of 5366 dry mandibles at the Smithsonian Institution revealed three cases of unilateral lingual defects superior to the mandibular foramen. The differential diagnosis includes a neuroma, neurolemmoma, hemangioma, or aneurysm of the inferior alveolar artery. The clinical significance of a vascular neoplasm or aneurysm would be the likelihood of increasing the risk of injecting the anesthetic solution directly into a blood vessel.
The effectiveness of rigid and semirigid fixation at various distances between Le Fort I osteotomy segments after different healing periods was evaluated in 16 Macaca fasicularis monkeys. The histologic findings revealed better healing with semirigid fixation.
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Freshly mixed, unset zinc-free and zinc-containing analgam was implanted in the right tibia of 32 rats. Half of the specimens were examined by the light microscope and the other half by the scanning electron microscope and x-ray microprobe analysis. It was found that amalgam is well tolerated by the rat osseous tissue, and there were no histologic reaction differences between zinc and zinc free amalgam. The surfaces of the implants were covered by an organic film at 3 weeks and with bone at later intervals. Very little corrosion products containing sulfur were observed on the amalgam surface at all intervals. Bone adjacent to the amalgam contained tin and sulfur irrespective of the presence of zinc in the alloy, indicating outward migration of specific components of the alloy.
Twenty-four cases of maxillary ameloblastoma from the files of the dental and oral division of the Armed Forces Institute of Pathology and the US Army Institute of Dental Research were reviewed. Clinical findings showed an average age of 45.6 years, a male-to-female ratio of 2.4:1, and an equal racial distribution between whites and blacks. Eighty-eight percent of the tumors occurred distal to the maxillary canine. A slowly enlarging mass was the primary clinical sign in more than 90% of the cases. Recurrences were seen in eight of the 16 cases on which follow-up information was received. The majority of the tumors had a mixed follicular histologic pattern. Therapy should consist of either surgical block excision or hemimaxillectomy. The surgeon must carefully weigh the potential danger of the neoplasm against the deformity and disability caused by the surgical procedure.
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Polyethylene tubes obturated flush at one end overfilled 2 mm. at the opposite end with unset Grossman's cement and gutta-percha were implanted in rat tibias. Microscopic evaluation of the specimens revealed that (1) the gutta-percha, Grossman's sealer, and polyethylene tubing are well tolerated by rat intraosseous tissue and (2) a canal overextended 2 mm. beyond the apex with Grossman's cement and gutta-percha produces an early mild to moderate inflammatory response which resolves by the end of 30 day's. The overfillings did not significantly compromise the healing of rat intraosseous tissue.
Wounds were prepared in the oral cavity of 15 rabbits and five dogs, and an enzyme-solubilized calfskin collagen was placed over the surgery sites on one side. The contralateral sides acted as controls. Results indicated that the membrane was biologically acceptable to the oral mucosa of rabbits and dogs. Th collagen did not cause any adverse reaction and may have been responsible for the clinical impression of slightly more rapid healing of the gingivae in dogs. Clinical implications of this material's utilization produce some exciting ideas for future research.
The natural history and histologic characteristics of a rare malignant neoplasm of tendons and aponeuroses are described, and a case is presented which originated in the right foot of a 19-year-old Caucasian woman who succumbed to the disease after 4 years. This case represents the first known example of metastasis to the oral cavity of this particular neoplasm.
Polyethylene tubes obturated flush at one end and 1 mm. short at the opposite end with gutta percha and Grossman's cement as the cementing media were implanted in rat tibias. The gutta-percha, the set Grossman's cement, and the polyethylene implant were well tolerated by the rat intraosseous tissues. There was no significant inflammatory response at either the flush end or the short end of the polyethylene implant.
In this article a few of the more recently emphasized and pertinent conditions that may affect the hard and soft palate have been discussed. The purpose of the article is not to present in all-inclusive classification of lesions occurring the palate. Disease of the palate may be local in nature or may reflect a systemic condition. Dentists must be conscious of the palate as the site of many possible pathoses. The prosthodontist in particular must observe and carefully evaluate the palate and insure its good health before he can prescribe a prosthesis to cover it. Dentistry provides a health service which affects the entire human organism and not just the oral cavity. Therefore an understanding of the varied nature of pathosis as it relates to the oral cavity, and especially the palate, is essential. Continuous surveillance of the palatal regions insures that the dentist's obligation to detect oral abnormalities in patients is in large measure fulfilled.
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An unusual case of odontogenic adenomatoid tumor in the mandible of an 11-year-old Ethiopian girl is described. This case is unique because of the extensive size of the tumor (12 cm), long duration, the number of associated impacted teeth (seven), the pronounced areas of radiopaqueness, the multiocular configuration, the anomalous tooth form, and the fact that deciduous teeth were involved.
Histologic examination was performed on the superior labial frenum obtained from 11 fresh biopsy and three autopsy specimens. The frena contained considerable dense collagen, loose connective tissue and elastic fibers. There were no muscle fibers in any of the frenum sections except the autopsy specimens, where it was seen in the vestibular tissue but not in the frenum proper.
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Explore the source record for details and available documents.