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Biomedical subjects

P J Prado

Publications and source records attributed to P J Prado.

7 recordsLinked to original sources

One-dimensional imaging with a palm-size probe.

A new portable magnetic resonance imaging device was built. Spatially resolved NMR was achieved by placing a gradient coil pair and a Helmholtz pair type radio-frequency probe in the gap between two antiparallel polarized permanent magnets. The flat face of the low-field (nu(proton) = 20 MHz) apparatus allowed for the study of arbitrarily large objects in situ. Relaxation time weighted 1D images were achieved over a 15-mm field of view by a single-point spin-echo sequence. A phase encoding time on the order of 200 micros permited the scanning of a wide range of heterogeneous materials.

Cost-Benefit Analysis↗

Single-point magnetic resonance imaging study of water adsorption in pellets of zeolite 4A.

The water uptake process in commercial type particles of zeolite 4A has been studied using a single-point MRI method. True proton density, T1, T2, and T*2 relaxation times were obtained with submillimetric resolution, overcoming the restrictions of short T*2 signals. The molecular mobility in nonequilibrium conditions has been characterized by relaxation time mapping. A clear reduction of the water sorption rate was observed by comparing MRI profiles of a loosely packed bed and gravimetric measurements of spread particles from the same sieved zeolite batch.

Adsorption↗

Relaxation time mapping of short T*2 nuclei with single-point imaging (SPI) methods.

New techniques for quantitative mapping of T1, T2, and T*2 are proposed, based on the single-point imaging (SPI) method, for materials with short nuclear magnetic resonance relaxation times which cannot be imaged with traditional methods. Relaxation times extracted from two-dimensional images of uniform doped agarose phantoms (T*2 approximately 60-210 microseconds) as well as hardened mortar (T*2 approximately 220 microseconds) and polymers (T*2 approximately 20-100 microseconds), using these techniques, agreed with bulk measurements. The method was then applied to a partially dried cylindrical concrete sample (T*2 approximately 115 microseconds).

Image Enhancement↗

The influence of shrinkage-cracking on the drying behaviour of White Portland cement using Single-Point Imaging (SPI).

The removal of water from pores in hardened cement paste smaller than 50 nm results in cracking of the cement matrix due to the tensile stresses induced by drying shrinkage. Cracks in the matrix fundamentally alter the permeability of the material, and therefore directly affect the drying behaviour. Using Single-Point Imaging (SPI), we obtain one-dimensional moisture profiles of hydrated White Portland cement cylinders as a function of drying time. The drying behaviour of White Portland cement, is distinctly different from the drying behaviour of related concrete materials containing aggregates.

Construction Materials↗

Concrete thawing studied by single-point ramped imaging.

A series of two-dimensional images of proton distribution in a hardened concrete sample has been obtained during the thawing process (from -50 degrees C up to 11 degrees C). The SPRITE sequence is optimal for this study given the characteristic short relaxation times of water in this porous media (T2* < 200 micros and T1 < 3.6 ms). The relaxation parameters of the sample were determined in order to optimize the time efficiency of the sequence, permitting a 4-scan 64 x 64 acquisition in under 3 min. The image acquisition is fast on the time scale of the temperature evolution of the specimen. The frozen water distribution is quantified through a position based study of the image contrast. A multiple point acquisition method is presented and the signal sensitivity improvement is discussed.

Image Processing, Computer-Assisted↗

NMR hand-held moisture sensor.

An open magnet design, hand-held NMR sensor head is presented. Wood moisture content and cement hydration tests demonstrate the potential of the tool for in-situ material assessment. The magnetic field distribution was adjusted by positioning blocks of permanent magnets using millimeter scale 3-dimensional magnetic field modeling. A low Q-factor circuit was used for spin-echo sequences with short echo times.

Magnetic Resonance Spectroscopy↗

Concrete/mortar water phase transition studied by single-point MRI methods.

A series of magnetic resonance imaging (MRI) water density and T2* profiles in hardened concrete and mortar samples has been obtained during freezing conditions (-50 degrees C < T < 11 degrees C). The single-point ramped imaging with T1 enhancement (SPRITE) sequence is optimal for this study given the characteristic short relaxation times of water in this porous media (T2* < 200 microseconds and T1 < 3.6 ms). The frozen and evaporable water distribution was quantified through a position based study of the profile magnitude. Submillimetric resolution of proton-density and T2*-relaxation parameters as a function of temperature has been achieved.

Cementation↗