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Biomedical subjects

P J Horsey

Publications and source records attributed to P J Horsey.

At least 19 recordsLinked to original sources
PubMed1987

The new generation gelatins. A review of their history, manufacture and properties.

Gelatin solutions of various kinds have been used as intravenous infusions since the First World War and belong to a heterogeneous group of fluids which tend to maintain the colloid osmotic pressure. They are produced by the breakdown of bovine collagen to yield solutions with a range of molecular weights. Anaphylactoid reactions are a rare but well-recognised complication of their use. The solutions help to fill a hiatus that exists between crystalloids and blood products.

Anaphylaxis↗
PubMed1987

Changes in cerebral blood flow during anaesthesia and surgery in the sitting position.

Serial measurements of global cerebral blood flow (CBF) were made in 15 patients undergoing elective neurosurgical procedures in the sitting position, using a modified intravenous 133Xenon technique. The mean supine CBF rose from 43 (+/-3) ml/100g/min to 62 (+/-6) ml/100g/min in the sitting position and remained elevated at the end of surgery at 62 (+/-5) ml/100g/min. Both increases in CBF were statistically significant with respect to baseline supine values.

Adult↗