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Biomedical subjects

P Henkind

Publications and source records attributed to P Henkind.

At least 19 recordsLinked to original sources
PubMed1992

Mortality and morbidity in patients with central retinal vein occlusion.

We investigated the risk of mortality and morbidity in 78 patients with central retinal vein occlusion (CRVO) followed for more than 2 years (mean follow-up 7.2 years). Thirteen subjects died at an average of 7.0 years after CRVO. Five subjects developed myocardial infarction at an average of 2.8 years after CRVO, and 1 developed a cerebrovascular accident 3 years after CRVO. Patients with CRVO do not carry a higher risk of mortality and morbidity than matched controls derived from national surveys.

Adult↗
PubMed1992

Idiopathic preretinal macular gliosis: a retrospective study of 200 patients.

The charts of the last 200 patients with idiopathic preretinal macular gliosis (IPRMG) seen in the Retina Service of Montefiore Medical Center, Albert Einstein College of Medicine, were reviewed. We found that IPRMG is a disease of older people, tends to have a nonprogressive course, and rarely causes severe visual loss. In our series, 91.5% of the patients were older than 50 years of age, 80% of eyes lost less than two lines of vision, and only 4% of eyes had a visual acuity 20/200.

Adult↗
PubMed1979

Schwann cell proliferations mimicking medullated retinal nerve fibers.

Ophthalmoscopically visible white patches in the optic nerve head and adjacent retina in a rhesus monkey histologically represented peripheral rather than central nervous myelin. This case of Schwann cell proliferations appearing as medullated retinal nerve fibers raises questions concerning the relationship of this phenomenon to developmental and acquired lesions of the optic nerve head in man.

Animals↗
PubMed1979

Chalazia.

Explore the source record for details and available documents.

Eyelid Neoplasms↗
PubMed1979

Microcysts of the human iris pigment epithelium.

Microcysts of the iris pigment epithelium have been described in association with diabetes mellitus, systemic mucopolysaccharidoses. Menkes's syndrome, and in neonates. Our study covers 68 cases obtained at necropsy. We specifically examined the iris pigment epithelium for vacuolation. We found that microcysts are more widespread than previously thought. In our series 57.3% of the cases reviewed by the light microscope showed microcysts. Of interest was the relationship of malignant neoplasm to iris pigment epithelium microcyst: 69.4% of cases with malignancy showed microcyst, whereas only 30% of the cases without neoplasms showed microcysts. Patients treated with exogenous steroid also had a raised incidence of microcysts.

Adrenal Cortex Hormones↗
PubMed1978

Some observations about retinal vascular-neuronal interrelationships.

The relationship between the intraretinal vessels of the human fundus and the surrounding neuronal tissue is discussed with regard to various disease states. Present evidence suggests that primary retinal neuronal death does not lead to secondary retinal capillary death. Primary retinal capillary non-perfusion generally leads to concomitant retinal neuronal degeneration, but if the occlusion takes place over a long period of time the surrounding neural retina may survive. It is suggested that many retinal degenerative changes, including retinal detachment, are due to primary retinal vascular alterations.

Humans↗
PubMed1978

Ocular neovascularization. The Krill memorial lecture.

The various vascular systems of the eye can undergo new vessel formation. In this presentation, I discuss new vessel growth in the cornea, lens, iris, ciliary body, choroid, retina, and optic nerve head. No single factor can explain all cases of ocular neovascularization; instead there are multiple factors which can affect the various susceptible vessels. Among the known vasculognic factors are: inflammation and its products, a hypoxic retina diffusable factor, the "tumor angiogenic factor," and possibly an aging factor. The different ocular beds possess differing sensitivity to the various vasculogenic stimuli; the iris and choroid being most sensitive and the retina and ciliary body least sensitive to such stimuli. Retinal neovascularization requires both a biochemical factor and a diseased retinal vascular bed for its induction. Ocular neovascularization is a dynamic process which requires a persisting stimulus or else the new vessels tend to regress. The normal eye seems to possess at least two antivasculogenic agents.

Anemia, Sickle Cell↗
PubMed1977

Retinal arterial occlusive disease in systemic lupus erythematosus.

Four patients with systemic lupus erythematosus (SLE) developed an unusual form of occlusive retinal arterial disease. The most prominent clinical features of this disorder were deposition of yellow-white material in retinal arterial walls and evidence of multifocal retinal arterial occlusion. Fluorescein angiographic findings included nonperfusion of the obstructed arteries and the retinal capillary beds fed by them, and fluorescein leakage at the sites of involvement of the retinal arteries. This ocular complication of SLE is presumably a manifestation of the widespread systemic vascular problems seen in this disorder. It may be more common in patients with lupus involving the CNS.

Adult↗
PubMed1977

The association of retinitis pigmentosa with preretinal macular gliosis.

A retrospective study of the histopathological features of retinitis pigmentosa was undertaken. A consistent finding in 10 out of 10 eyes from 6 patients with retinitis pigmentosa was the presence of a preretinal membrane. The frequency of this finding has not been noted previously. Preretinal gliosis may well be responsible for the production of the abnormal glinting fundus reflex seen at the posterior pole in retinitis pigmentosa.

Adult↗
PubMed1977

Conjunctival melanocytic lesions. Natural history.

Conjunctival melanocytes are like those of the skin and benign and malignant lesions composed of conjuctival melanocytes act much like those of skin. Conjunctival naevi are common and usually benign. Conjunctival melanomas are rare and arise de novo, from pre-existing junctional naevi or from intraepithelial melanomas either superficial spreading melanoma (SSM) or Hutchinson's freckle (HF). It is important to utilize the newer data about skin melanomas in any consideration of the diagnosis and prognosis of melanotic conjunctival lesions. Until more information is gathered we cannot provide an accurate assessment of the natural history of malignant conjunctival melanomas.

Aged↗