Search PubMed⌕ Search

Biomedical subjects

P Heeg

Publications and source records attributed to P Heeg.

At least 55 records · Page 3Linked to original sources
PubMed1994

Automated processing of endoscopic surgical instruments.

This paper deals with the requirements for automated processing of endoscopic surgical instruments. After a brief analysis of the current problems, solutions are discussed. Test-procedures have been developed to validate the automated processing, so that the cleaning results are guaranteed and reproducable. Also a device for testing and cleaning was designed together with Netzsch Newamatic and PCI, called TC-MIC, to automate processing and reduce manual work.

Automation↗
PubMed1994

[Infections caused by Flavobacterium meningosepticum in patients in a neonatal intensive care unit].

During a period of three and a half months 7 neonates from a neonatal intensive care unit became infected by F. meningosepticum, serotype B. The pathogens could be isolated from the tracheal secretions and--less frequently--from throat swabs, gastric juice and nose swabs. Environmental sampling led to the isolation of F. meningosepticum from the humidification fluid of the respirator, from vaporizers as well as from the artificial ventilation tubing. F. mengingosepticum was found in the water of humidifiers from 3 children, who developed neither a colonization nor an infection. In a number of cases the patients' environment was contaminated with F. meningosepticum prior to colinization or infection. Nearly identical resistance patterns against the antibiotics tested, could be demonstrated for the isolated strains. The primary source of infection could not be identified, it is supposed however that the index patient had been admitted to the hospital nine months before. A strict hygienic policy, like consequently performed hand hygiene, adequate processing of ventilation equipment and application of sterile tubings led to extinction of the infections. During subsequent environmental controls, F. meningosepticum could not be isolated.

Anti-Bacterial Agents↗
PubMed1992

Evaluation of the efficacy of surgical hand disinfection following a reduced application time of 3 instead of 5 min.

The guidelines of the German Society for Hygiene and Microbiology for the evaluation of disinfectants suggest an application time of 5 min for surgical scrub products. In a comparative investigation, which included the more important basic substances and agents, tests were carried out to investigate whether it was possible to reduce the application time to 3 min without losing efficiency in both the immediate as well as the prolonged effect of bacterial reduction. It was found that this could be achieved by certain products, depending on the formula and type of active substance. Thus, a reduced application time of 3 min can be considered for the evaluation of surgical scrub disinfectants for national and international guidelines.

1-Propanol↗
PubMed1991

[Disinfection of dental impressions].

The need for disinfection of dental impressions is generally postulated. While many disinfectants for elastomeric impression materials have been recommended for at least ten years, several authors recently described suitable disinfectants for alginate impressions. Disinfectants for reversible hydrocolloid materials are in the phase of practical testing, and show promising first results. Under practical and scientific aspects further investigations are necessary to evaluate standards and standardized testing procedures.

Alginates↗
PubMed1990

[Antisepsis of mucous membranes--current status and aspects of future development].

The mucous membranes colonized by high numbers of microorganisms play a major role as a source of nosocomial infections. According to clinical requirements it seems reasonable to distinguish three modes of application of antiseptics: 1. single prophylactic (prior to mucosa-penetrating interventions), 2. repeated periodical (wound care, treatment of oral cavity in intubated patients, decontamination of granulocytopenic patients), 3. therapeutic (local mucosal infections) including treatment of carriers to prevent transmission and spread of pathogens. Active agents commonly in use are PVP-iodine, cation-active detergents (e.g. chlorhexidine), oxygen-releasing compounds and organic mercury compounds. Presently chlorhexidine and PVP-iodine are the most frequently applied of these antiseptics while the organic mercury compounds are less important because of limited efficacy, toxicological and ecological problems. Preliminary data from investigations using a newly developed antiseptic, octenidine, a bispyridine compound, demonstrate reduction factors comparable to those obtained by PVP-iodine. Yet no standardized test methods for the efficacy of different substances and methods of application have been established.

Colony Count, Microbial↗
PubMed1990

[Microbiology studies of intra- and postoperative autotransfusion in orthopedics].

In order to determine the risk of bacterial contamination of blood during autotransfusion, blood samples were taken from the autotransfusion system of 25 consecutive total hip replacements at various stages and at different times (9 samples per patient). According to the same principle, samples were taken from the identical system after processing the postoperative drainage blood. Since the danger of contamination depends on the quality of the air which is sucked into the autotransfusion system along with the blood, we also measured the amount of bacteria in the air in two different operating rooms: Horizontal laminar air flow was provided for 20, conventional ventilation for a further 5 operations. Evaluation of airborne contamination in the operating rooms showed at most 656 cfu/m3 in the conventionally ventilated room and at most 344 cfu/m3 in the room with laminar air flow. Micrococci and peptococci were cultivated from 2 samples out of 225. The isolates were derived from 2 different patients (1 in the LAF-OR, 1 in the conventionally ventilated OR); both samples were taken from the retransfusion bag towards the completion of surgery. From these results we conclude that even in a conventionally ventilated operating room during primarily aseptic surgery intraoperative autotransfusion does not involve an increased risk of infection. This also applies to the retransfusion of processed blood from Redon drainages using the identical autotransfusion set.

Air Microbiology↗
PubMed1989

[The antimicrobial effect of an alginate with an antiseptic admixture].

Attempts to simplify impression disinfection lead to the production of an aseptic alginate impression material (Blueprint asept, De Trey/Dentsply, Konstanz, Germany). This study describes the aseptic properties of this new type of impression material. The in-vitro part of the experiments showed a reduction of Staphylococcus aureus by 6 and of Pseudomonas aeruginosa by 4 log steps after 60 min, and of Candida albicans by at least 3 log steps after 15 min of exposure. Under in-vivo conditions oral bacteria residing on the impression surfaces were reduced by nearly 4 log steps. Although the aseptic properties of the material were demonstrated, the biological acceptance, dimensional stability and compatibility with gypsum have to be tested in further studies.

Alginates↗
PubMed1988

[Risk of infection due to catheter reuse].

Cardiac catheters assigned for reprocessing revealed only minor bacterial contamination. Random samples taken from reprocessed catheters were sterile and free from pyrogens. Among a total of 461 prospectively surveyed patients, in 16 cases a short increase of temperature up to 37.5 degrees C was observed, which appeared independent from the application of reprocessed catheters. None of the patients developed fever or symptoms of catheter-related infection.

Bacterial Infections↗
PubMed1986

Bacterial colonization and occurrence of Legionella pneumophila in warm and cold water, in faucet aerators, and in drains of hospitals.

Warm and cold water as well as water from wash basin drains and faucet aerators was examined to determine the number of viable and dead bacteria by culture and by staining and to establish the spectrum of species with special consideration of Legionella pneumophila. The relation between the number of Legionella pneumophila, the temperature, and the iron content of the water was determined in three separate warm water systems. High colony counts (up to 8.9 X 10(5) colony-forming units), were detected in both warm and cold water at certain sampling sites. The most prevalent genera were Pseudomonas, Bacillus, Flavobacterium, Acinetobacter, and Moraxella. Legionella pneumophila was found in every building in 35 of 150 warm samples and in 1 of 43 cold water samples. The highest water temperature of a sample containing Legionella pneumophila was 64 degrees C. The correlation between high colony counts and the occurrence of Legionella pneumophila in the samples was not significant. High iron concentrations, however, appear to have a positive effect on the growth of Legionella pneumophila.

Equipment and Supplies, Hospital↗
PubMed1985

[Demonstration of Clostridium difficile and toxin B in patients at a university clinic].

107 stool specimens from not hospitalized individuals and 69 stool specimens from 61 hospitalized patients (Internal Medicine) were examined for C. difficile and toxin B. Included were 42 specimens of 33 female patients of the department of maxillo-facial surgery, receiving prophylactic clindamycin and 7 samples from the ward staff. From the samples of the first group, C. difficile was isolated in one case (0.93%), whereas 8 out of 61 internal patients (13%) were positive for C. difficile by culture and/or toxin test. In 12 out of 33 surgical patients (36%), C. difficile and/or toxin could be detected in the stool. Examination of the ward staff was negative. Environmental samplings on the ward, comprehending 246 contact cultures, resulted in the isolation of C. difficile from 25 plates (10.1%). The majority of the patients showed no symptoms or slight diarrhea. Only 5 patients required vancomycin therapy. Frequency and clinical significance of C. difficile isolation is discussed under these aspects.

Bacterial Proteins↗
PubMed1984

[Experimental and clinical studies of the efficacy of an antimicrobial incision drape].

The antibacterial activity of an antimicrobial incise drape containing povidone-iodine was compared to a normal drape by experimental and clinical investigations. In vitro, no difference in the survival rate of six bacterial species depending on the kind of the drape, could be demonstrated. Clinical studies by contact cultures, postoperatively taken from the skin after removal of the drape, yielded no significant difference in the recolonisation of the skin during the operations. The importance of the preoperative, antimicrobial preparations of the skin is discussed.

Bacteria↗