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Biomedical subjects

P Haussmann

Publications and source records attributed to P Haussmann.

At least 37 records · Page 2Linked to original sources

[Closure of rheumatic palmar perforations of the wrist capsule with a flap of retinaculum flexorum].

In 53 hands with rheumatoid arthritis, bony spurs of the scaphoid and trapezium were found perforating the capsule of the radial wall of the carpal tunnel. After removal of the spurs, the remaining capsular defect was covered by a flap of the flexor retinaculum. The flap is raised from the flexor retinaculum in a width of approximately 15 mm by parallel transverse incisions and is based radially. Then it is brought down to the defect and sutured to the local ligaments. The blood supply of the retinacular flap is well preserved. The flap provides a reliable cover of the capsular defect as well as a smooth gliding surface for the flexor tendons.

Arthritis, Rheumatoid↗

[Malignant schwannoma of the median nerve].

The case of a 52-year old patient is described who was operated on for pronator-teres syndrome. Eight months postoperatively reoperation was necessary because of recurrent pain. The median nerve showed haemorrhagic necrosis in the region of the pronator teres muscle with an extensive intrafascicular swelling of the adjacent proximal and distal nerve segments. After resection of the median nerve, the histological examination revealed a benign schwannoma. Reconstruction of the median nerve was performed by interfascicular nerve grafting. Three months later severe pains recurred in the forearm which had to be opened in an emergency operation. Extensive haemorrhagic necrosis was evident. The histological diagnosis was now malignant schwannoma. Upper arm amputation was performed and later a functional prosthesis was fitted. Three years after the amputation multiple metastases occurred; the patient died within three months.

Amputation, Surgical↗

[Palm creases and anatomy. Palmar print of 166 patients with surgically treated carpal tunnel syndrome].

The dermatoglyphics are genetically determined as well as anatomical variations are unique in every person. The following paper coordinates some variations in furrows of the hand with anatomical situations that can be found when operating a Carpal tunnel syndrome. In 166 patients the preoperative handprint was compared to the anatomy found. Some anatomical variations were found to have their expression in certain furrows.

Carpal Tunnel Syndrome↗

[Alloplastic partial replacement of the scaphoid bone].

Operative treatment for non-union of the carpal scaphoid bone with a small proximal fragment often presents some difficulties. A complete Silastic carpal scaphoid replacement does not always fit well because the shape and dimensions of the implant differ from the natural carpal scaphoid bone. The proximal fragment looks more like the lunate bone and so a Silastic carpal lunate implant may be used to replace the proximal fragment of the scaphoid while the well preserved distal fragment remains in place. This prevents disturbance of the intercarpal joint composition and improves stability of the base of the thumb. Five patients have been treated in this manner. The procedure is described in detail.

Arthroplasty↗

[Free primary tissue transfer from non-replanted finger parts].

In mutilating multidigital injuries, nonreplantable parts of amputated fingers may serve well as donor sites for reconstruction of another severely damaged finger. A case of a 38 year old man is reported who suffered a severe multidigital injury of his left hand by a milling-machine. An extensive soft tissue defect of the middle finger was covered with a neurovascular flap from the nonreplantable index finger after the fractured middle phalanx was stabilized by osteosynthesis and bone grafting and the flexor tendons were sutured. The flap contained a neurovascular bundle and a dorsal vein which were sutured to the corresponding palmar artery and nerve and dorsal vein of the finger by microsurgical technique. In multidigital mutilating injuries the immediate use of a microvascular flap from a nonreplantable part is recommended to improve healing and later use of the remaining digits.

Adult↗

[Intratruncal fascicular compression of the anterior interosseous nerve].

Two patients are reported who were operated for clinically apparent anterior interosseous nerve compression syndrome (Kiloh-Nevin). In contrast to the cases described in the literature, no external compression was found anywhere in the course of the nerve. However, the nerve bundles forming the nerve within the main median nerve proximal to the elbow were found to be compressed in isolation. The median nerve was otherwise normal. In one case, the compressed nerve was excised and grafted and, in the other case, a perineural neurolysis was performed. In both cases, the paralysis improved. Two cases in the literature are discussed, in which similar findings were present.

Elbow↗

[Oligofascicular median nerve compression syndrome].

The anterior interosseous nerve syndrome is described as a compression of this nerve by a fibrous band in the region of the pronator teres or the flexor digitorum superficialis muscle. We report a case which appeared clinically as an anterior interosseous nerve syndrome but on exploration no fibrous band was present. The compression involved exclusively the fascicles in the main trunk of the median merve which form more distally the anterior interosseous nerve. The damage fascicles were resected and interfascicular nerve grafting was performed. After 16 months motor function has recovered well. Recently a similar case was observed.

Adult↗

[Isolated traumatic lesions of the motor nerve branches in the hand].

Isolated injuries of the motor branches of the median and ulnar nerve in the hand are rare. The resulting loss of function is so important that primary or secondary repair is necessary. Using microsurgery techniques the results are very satisfying. The procedure is demonstrated in three cases: 1. Primary perineural suture in a case of double severance of the motor branch of the median nerve caused by the blow of an axe. 2. Resection of neuroma and secondary suture of the motor branch of the median nerve after former knife cut. 3. Bridging a gap in the deep motor branch of the ulnar nerve by autologous nerve grafting after former stab injury of the hypothenar eminence. In all patients denervation after the injury as well as regeneration in the healing process was demonstrated by myography.

Adult↗

[Surgical treatment of the ruptured ulnar collateral ligament of the metacarpophlangeal joint of the thumb].

The diagnosis of ruptured ulnar collateral ligament of the metacarpo-phalangeal joint of the thumb is made from characteristic findings and special radiograms. Without treatment, impairment of hand function will result. Only in a few cases will conservative treatment be successful; the reasons are explained. 26 cases of total rupture of the collateral ligament and their surgical treatment are reported. 16 fresh ligamentous injuries were treated by suturing directly (n = 2), by pull-out wire technique (n = 10), and by screw osteosynthesis (n = 4). The ligament was reconstructed with a free tendon graft in 8 cases of old ligamentous injuries, while the remaining 2 cases were repaired using a pull-out wire. After treatment, all metacarpo-phalangeal joints showed full stability and all patients without discomfort. Restriction of mobility results much more from secondary than from primary treatment. Therefore, we recommend primary surgical treatment of the ruptured ulnar collateral ligament of the metacarpo-phalangeal joint of the thumb.

Adolescent↗

[Unusual causes of the carpal tunnel syndrome].

In 193 cases of carpal tunnel exploration, carried out because of compression of the medium nerve, we have encountered 15 unusual findings (7.8%). This emphasizes the necessity for thorough exploration of the carpal tunnel. Four unusual disease processes are described, which led to a median compression syndrome: Tuberculous tenosynovitis, lipomatous hyperplasia, chondroma of a superficial flexor tendon and monofascicular neurinoma of the median nerve.

Adult↗

[Neglected perforation of a plastic implant after flexor tendon injury].

The remarkable resistance to infection of the new tendon sheath induced by silicone rubber spacers is demonstrated in a case of a 36 years old woman who received a silicone rubber spacer after flexor tendon injury. The patient did not return for the planned tendon grafting in spite of repeated requests. After two years she came back with an ulcer on her finger tip where the silastic rod was visible. 6 months previously the rod had extruded and been lost, found again and replaced. No inflammation existed, except ulceration at the site of perforation. The ulcer healed within a few days after removal of the spacer and local irrigation. The patient refused any further treatment.

Adult↗

[Management of extensive avulsion injury of the hand].

The case of a 25 years old industrial worker is reported, who suffered an extensive avulsion of his left hand in a rubber roller injury. The middle and ring fingers hand to be amputated. The skin loss was covered simultaneously by an axillary pedicled flap for the thumb, two pedicle flaps from the upper arm for the index and small fingers and split thickness skin grafts for the dorsum of the hand. In a second stage, sensation of the tips of thumb and index finger was restored by two innervated full thickness skin grafts from the dorsum of the foot.

Accidents, Occupational↗

[Experimental studies on the effect of incisions with the electric knife on wound healing].

In 114 albino rats the healing of incisions by scalpel and of several kinds of electrosurgically induced skin wounds was studied. The authors used the electrotome Martin 800 RFS. Incisions with the least coagulation which were the most blood-drenched healed best. These wounds were the tightest. Much coagulation distinctly worsened wound healing. That depends not only on the adjustment of the electrotome but also on the electrodes and the velocity of cutting. Proper cutting technique, adequate form of the electrode, and optimal amperage are required to combine the advantages of the less-bleeding non-pressing cut with satisfactory wound healing. The best results of the experiments are reported in detail.

Animals↗

The role of mitochondria in carbon catabolite repression in yeast.

The role of mitochondria in carbon catabolite repression in Saccharomyces cerevisiae was investigated by comparing normal, respiratory competent (RHO) strains with their mitochondrially inherited, respiratory deficient mutant derivatives (rho). Formation of maltase and invertase was used as an indicator system for the effect of carbon catabolite repression on carbon catabolic reactions. Fermentation rates for glucose, maltose and sucrose were the same in RHO and rho strains. Specific activities of maltase and invertase were usually higher in the rho-mutants. A very pronounced difference in invertase levels was observed when cells were grown on maltose; rho-mutants had around 30 times more invertase than their RHO parent strains. The fact that rho-mutants were much less sensitive to carbon catabolite repression of invertase synthesis than their RHO parents was used to search for the mitochondrial factor(s) or function(s) involved in carbon catabolite repression. A possible metabolic influence of mitochondria on this system of regulation was tested after growth of RHO strains under anaerobic conditions (no respiration nor oxidative phosphorylation), in the presence of KCN (respiration inhibited), dinitrophenol (uncoupling of oxidative phosphorylation) and of both inhibitors anaerobic conditions and dinitrophenol had no effect on the extent of invertase repression. KCN reduced the degree of repression but not to the level found in rho-mutants. A combination of both inhibitors gave the same results as with KCN alone. Erythromycin and chloramphenicol were used as specific inhibitors of mitochondrial protein synthesis. Erythromycin prevented the formation of mitochondrial respiratory systems but did not induce rho-mutants under the conditions used. However, repression of invertase was as strong as in the absence of the inhibitor. Chloramphenicol led only to a slight reduction of the respiratory systems and did not affect invertase levels. A combination of both antibiotics had about the same effect as growth in the presence of KCN. The results showed that mitochondria are involved in carbon catabolite repression and they cause an increase in the degree of repression. These effects cannot be due to mere metabolic activities nor to factors made on the mitochondrial protein synthesizing machinery. This regulatory role of mitochondria is observed as long as an intact mitochondrial genome is maintained.

Carbon↗

[Primary and secondary microsurgical suturing of nerve injuries of the upper extremities. Results of treatment (author's transl)].

In the course of two years, 53 traumatic nerve severances of the upper extremity were sutured microsurgically at the Freiburg University Surgical Hospital. Continuity was restored by primary suture in 29 cases, by secondary suture in 4 cases and by transplantation in 20 cases. The first reinnervation potentials showing in the EMG served as evidence of the motor regeneration. With primary sutures, incipient voluntary innervation was observed after 2 1/2 months, but only after 9 months with nerve transplantation. Favourable conditions given, the authors therefore prefer the microsurgical primary suture to transplantation.

Arm↗