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P Høllsberg

Publications and source records attributed to P Høllsberg.

4 recordsLinked to original sources
PubMed1990

Markers for human placental trophoblasts in two-dimensional gel electrophoresis.

Primary cultures of trophoblasts established from human term placentae showed high viability and reproducibility. Two-dimensional gel patterns obtained by metabolically labeling the trophoblasts with [35S]-methionine demonstrated that their pattern of gene expression was stable during the 6-d period investigated. Gel analysis demonstrated the keratins 7, 8, 14, 17, 18, and 19. Analysis of the gel pattern confirmed the presence of a small proportion of contaminating fibroblasts and lymphocytes. The gel patterns were compared with that of skin fibroblasts, peripheral lymphocytes, and epithelial cells to identify a group of proteins that are enriched in the trophoblasts and thus may be used as marker for these cells.

Cells, Cultured↗
PubMed1989

The phagocytic activity of monocytes and polymorphonuclear leucocytes against viral antigens as measured by chemiluminescence in patients with multiple sclerosis.

Twenty-two patients with Multiple Sclerosis in different stages of the disease were investigated in a chemiluminescence-assay and compared with a similar number of healthy individuals. The reactivity of peripheral blood monocytes to different viral antigens was followed by measurement of both the immediate oxidative activity and the development of activity through a 85-minutes period. The patients with a progressive course of the disease showed a high activity and reached maximum activity in a shorter time than the other groups, indicating an activation of the monocytes in these patients.--The patients in steady state showed a rather low activity, compared with both the other patient groups and the control group. A possible significance of these findings is discussed. The activity of the polymorphonuclear cells did not show differences in activity between the groups.

Adult↗
PubMed1988

MS and the group-specific component.

Sera from 95 MS patients and 227 control persons were examined by IEF to determine the Gc genotype. There was no correlation between MS and the distribution of Gc genotype (0.70 less than P less than 0.80) nor Gc alleles (0.80 less than P less than 0.90) although such a correlation is generally accepted on the basis of a smaller material. Furthermore, Gc correlated with neither disease course nor with the age of disease onset.

Alleles↗