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Biomedical subjects

P H ter Meulen

Publications and source records attributed to P H ter Meulen.

4 recordsLinked to original sources

A conservative treatment of phimosis in boys.

OBJECTIVE: The aim of this study was to evaluate the efficacy of topical applications of clobetasol propionate cream in the treatment of phimosis in boys and a comparison of the results presented with an overview of the current studies. METHODS: In a prospective study, 94 boys (mean age 5.5 years) were treated with topical applications of 0.05% clobetasol propionate cream twice daily. The prepuce was treated for 1 month, with an attempt at prepuce retraction after 14 days. The boys were evaluated after 1 month of treatment and every 3 months during follow-up. RESULTS: Of the 94 boys, 91 were available for follow-up, of whom 42 boys (46.1%) achieved complete retraction of the prepuce, 24 (26.4%) had only preputial adhesions and 4 (4.4%) had partial retraction. Twenty-one boys (23.1%) had no response. The treatment was continued in 13 boys with good results eventually. Seven boys (7.7%) had recurrence after a mean follow-up of 4.3 months (range 2-7). No side effects were noted. Circumcision was necessary in 24 of the 91 boys (26.4%). The mean follow-up was 11.0 months (range 3-18). CONCLUSIONS: Local application of clobetasol propionate cream is a simple, safe and effective treatment for phimosis in boys and avoids circumcision and its associated risks. It should be offered first instead of circumcision.

Administration, Topical↗

Focal intraperitoneal fat infarction.

Focal intraperitoneal fat infarction, e.g. epiploic appendagitis and segmental omentum infarction, may mimic almost every acute abdominal condition. The symptoms of this benign and self-limiting disease will disappear without treatment. The etiology, symptoms, diagnosis (mainly with ultrasound and CT scan) and course of the disease are being described. An atypical case history with uneventful recovery without medical or surgical treatment is presented.

Abdominal Pain↗

[Epiploic appendicitis].

A 50-year-old woman presented with sudden onset of localised pain in the right and later the left lower abdomen, without other complaints. Only tenderness in the left lower abdomen was noted at physical examination. The ESR (25 mm/1st hr) and C-reactive protein (25 mg/l) were slightly elevated. The ultrasound (US) revealed a solid ovoid non-compressible hyperechoic mass (diameter 26 mm) at the point of maximum tenderness. The CT scan confirmed the presence of this lesion which appeared to be an infarction of an epiploic appendix with subsequent inflammation, called primary epiploic appendagitis. On conservative therapy the pain resolved in four weeks. The follow-up US and CT showed disappearance of the lesion after 35 days. When epiploic appendagitis is suspected, an US followed by CT is helpful to confirm the diagnosis and to avoid unnecessary treatment with antibiotics or operation.

Abdominal Pain↗

A study on the feasibility of vesicomyotomy in patients with motor urge incontinence.

OBJECTIVE: To study the feasibility of bladder autoaugmentation in patients with motor urge incontinence. PATIENTS AND METHODS: The clinical and urodynamic data of 5 patients were analyzed before and after treatment. All patients suffered from unstable bladders with a variable bladder capacity. All patients had urodynamic evaluation after 3 months. RESULTS: Three months after autoaugmentation 1 patient was continent while 4 were still incontinent. The continent patient had a stable bladder, whereas the others still suffered from unstable bladder contractions despite increased bladder capacity and leak point pressure. CONCLUSION: We did not succeed in abolishing bladder instability. Although our experience is limited, we cannot recommend vesicomyotomy as a routine procedure for motor urge incontinence at this time.

Adult↗