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Biomedical subjects

P Granger

Publications and source records attributed to P Granger.

At least 55 records · Page 3Linked to original sources
PubMed1971

Angiotensin-forming enzyme in brain tissue.

A renin-like enzyme is present in brain tissue and is independent of kidney and plasma renin. In the presence of homologous substrate it forms angiotensin. Administration of aldosterone significantly decreases this angiotensinforming enzyme activity, while administration of progesterone markedly enhances it.

Aldosterone↗
PubMed1970

Autopsy study of adrenals in unselected normotensive and hypertensive patients.

The records of the Hôtel-Dieu Hospital of Montreal, a general teaching hospital, provided 2425 consecutive autopsies done between January 1, 1955 and January 1, 1965. According to the diagnostic criteria used, 44.2% of the patients were hypertensive. Adrenal adenomas, nodules or hyperplasia were found in 7% of the hypertensive patients and in only 1.9% of the normotensive ones. The most frequently encountered lesion was adenoma (4.2% in the hypertensive population and 1.1% in the normotensive one). These results constitute supportive evidence for a low incidence of "normokalemic primary aldosteronism".

Adenoma↗