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Biomedical subjects

P Goodwin

Publications and source records attributed to P Goodwin.

89 records · Page 5Linked to original sources

'Look up gently'.

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Eye Diseases↗

Caroline.

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Female↗

Lipid composition of aorta of Watanabe heritable hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Plasma lipid composition determines aortic lipid composition of hypercholesterolemic rabbits.

Aortic and plasma lipid compositions were compared during a 12-month period in Watanabe heritable hyperlipemic (WHHL), comparably hypercholesterolemic fat-fed, and age-matched control normolipidemic rabbits to determine whether exposure to equivalent degrees of endogenous or exogenous hypercholesterolemia led to differences in the composition and concentration of lipids deposited in the artery wall. Although there were marked differences in the distribution of cholesterol among the lipoproteins in the WHHL versus the fat-fed rabbits, the contents of both free and esterified cholesterol were elevated to an equivalent degree in the aorta and plasma. In contrast, the triglyceride content of both the plasma and aorta were elevated only in the WHHL rabbits. However, aortic total phospholipids were increased in both the WHHL and fat-fed animals as compared to control rabbits. In the control rabbits, there was an age-dependent enrichment in aortic relative to plasma cholesteryl-oleate consistent with low density lipoprotein (LDL) receptor-directed intracellular cholesteryl ester processing. In contrast, enrichment in cholesteryl-oleate in aortae relative to plasma was not detected in either WHHL or fat-fed groups, suggesting that the plasma cholesteryl ester composition was the primary determinant of the aortic cholesterol composition. Thus, during chronic hypercholesterolemia, deposition of lipids in the artery wall appears to be determined by plasma lipoprotein levels and composition if the LDL receptor is either absent on a genetic basis or suppressed due to a high-fat, high-cholesterol diet.

Animals↗

Strabismus: diagnosis and management.

The problem of squint can pose problems which extend far beyond the limits of cosmetic considerations. To coincide with National Squint Awareness Week, co-ordinator Pat Goodwin describes the aetiology, treatment and management of the various conditions associated with squints.

Child↗

Seeing it straight.

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Female↗

Occupational medicine content of Oregon family physician practices.

BACKGROUND: Little has been published in the medical literature about the occupational medicine content of family practice. Little is known about the educational interventions needed for family physicians to improve the care they provide to patients suffering from occupational-related disorders. METHODS: A questionnaire based on a curriculum in occupational medicine proposed by a subcommittee of the Education Committee of the American Academy of Family Physicians for the guidance of family practice residency directors was sent to a random sample of 100 Oregon family physicians from a total of approximately 570 active practicing members of the Oregon Academy of Family Physicians. Ninety-three completed questionnaires were returned. RESULTS: Occupational medicine constituted a significant part (14 percent) of the practices of Oregon family physicians. The respondents rated management of chronic disability, disability determination, repetitive trauma disorders, and legal issues as the most important occupational medicine problems in their practices. These issues were also those about which they thought they needed additional training. CONCLUSIONS: Education in occupational medicine for family physicians must be better tailored to fit their needs and their priorities. The responses to this survey of practicing family physicians in Oregon suggest that more training in the areas of chronic disability management, disability determination, the management of repetitive trauma disorders, and legal aspects of occupational disorders is needed.

Curriculum↗

Partnership in action.

Patient participation groups do work. Pat Goodwin explains how she has been able to give something back to the practice where she has been registered for over 15 years.

Consumer Organizations↗