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Biomedical subjects

P Gomez

Publications and source records attributed to P Gomez.

65 records · Page 4Linked to original sources
PubMedDate not supplied

Diurnal variation in body temperature of Gambian children.

Measured fever often forms the basis for defining clinical malaria episodes in children from endemic areas. We measured body temperature every 3 h from 08:00 to 20:00 in 69 children aged 1-5 years during the malaria season in a rural area of The Gambia. Body temperature varied on average by more than one degree Celsius during the course of a day. Mean temperatures were lowest in the early morning and highest in the afternoon. There was a strong positive association between air temperature and body temperature. In highly endemic areas, researchers who use measured fever to assess clinical malaria episodes in population-based surveys should standardize the time of day at which temperature is assessed.

Body Temperature↗
PubMedDate not supplied

Thyroid dysfunction after radiation therapy in head and neck cancer patients.

INTRODUCTION: The reported incidence of hypothyroidism following surgery and/or radiation therapy for head and neck cancer varies widely. Most patients undergo thyroid lobectomy during laryngectomy. Standard radiation treatment portals often include the thyroid gland. The insidious development of hypothyroidism may be misdiagnosed. This study examines the incidence of thyroid dysfunction in the setting of head and neck cancer therapy. MATERIALS AND METHODS: Thyroid function tests were performed on 100 consecutive patients treated in the head and neck tumor clinic. Statistical inferences on proportions were made using chi-square analysis. RESULTS: Therapy included surgery only (10 patients), radiation therapy only (28 patients), and combined therapy (62 patients). These patients experienced thyroid dysfunction in 0%, 29%, and 45% of individuals respectively. These differences were statistically significant (P < .05). The highest rate of dysfunction (69%) was associated with patients undergoing laryngectomy and radiation therapy. When laryngectomy was not performed, thyroid dysfunction occurred in 28%. CONCLUSION: The likelihood of thyroid dysfunction after radiation therapy is high particularly when combined with surgery in which thyroid lobectomy is performed and the contralateral lobe is potentially devascularized. These results suggest that radiation therapy is a primary factor in alteration of thyroid function. We recommend that routine thyroid function testing be part of follow-up of all head and neck cancer patients.

Chi-Square Distribution↗
PubMedDate not supplied

Modelling serial position curves with temporal distinctiveness.

We offer a critique of the temporal distinctiveness model of serial position effects (Nairne, Neath, Serra, & Byun, 1997). The temporal distinctiveness model combines a precise definition of stimulus distinctiveness with a memory perturbation process. The critique is empirically motivated-we show that with a more complete analysis, the temporal distinctiveness model does not adequately account for Nairne et al.'s experimental data. To better account for the data, we independently modified two components of Nairne et al.'s model: the mathematical form of the definition of temporal distinctiveness and the mathematical form of the mapping from distinctiveness to free-recall probabilities. Both of these modifications provided for better fits. Yet both Nairne et al.'s definition and our modified definition are fairly arbitrary. We show that a significant challenge to this approach is to find theoretically motivated constraints of the temporal distinctiveness model while providing for adequate fits to data.

Humans↗
PubMedDate not supplied

Advancing the role of participatory communication in the diffusion of cancer screening among Hispanics.

Based on previously demonstrated methods, a cancer prevention program combining media and interpersonal communication was conducted in a Texas border city (Brownsville) in 1995-1996. To evaluate the program a quasi-experimental panel design study followed 107 women in a program site and 105 women in a comparison site from 1994 to 1996. Women in the program site reported an increase in levels of Pap screening adherence.

Adult↗
PubMedDate not supplied

Dried blood spots collected on filter paper: an international resource for the diagnosis and genetic characterization of human immunodeficiency virus type-1.

The collection of dried blood spots (DBS) on filter paper provides a powerful approach for the development of large-scale, population-based screening programs. DBS methods are particularly valuable in developing countries and isolated rural regions where resources are limited. Large numbers of field specimens can be economically collected and shipped to centralized reference laboratories for genetic and (or) serological analysis. Alternatively, the dried blood can be stored and used as an archival resource to rapidly establish the frequency and distribution of newly recognized mutations, confirm patient identity or track the origins and emergence of newly identified pathogens. In this report, we describe how PCR-based technologies are beginning to interface with international screening programmes for the diagnosis and genetic characterization of human immunodeficiency virus type 1 (HIV-1). In particular, we review recent progress using DBS specimens to resolve the HIV-1 infection status of neonates, monitor the genetic evolution of HIV-1 during early infancy and establish a sentinel surveillance system for the systematic monitoring of HIV-1 genetic variation in Asia.

AIDS Serodiagnosis↗
PubMedDate not supplied

Improving access to health care in Latino communities.

Public debate about health care reform often focuses on the need for health insurance coverage, but in Latino communities many other barriers also inhibit access to medical care. In addition, basic public health services often go underfunded or ignored. Thus, health care reform efforts, nationally and in each State, must embrace a broader view of the issues if the needs of Latino communities are to be served. This report reviews and summarizes information about the mounting problems Latino communities face in gaining access to medical care. Access to appropriate medical care is reduced by numerous financial, structural, and institutional barriers. Financial barriers include the lack of health insurance coverage and low family incomes common in Latino communities. More than 7 million Latinos (39 percent) go without health insurance coverage. Latinos without health insurance receive about half as much medical care as those who are insured. Structurally, the delivery system organization rarely reflects the cultural or social concerns of the communities where they are located. Therefore, providers and patients fail to communicate their concerns adequately. These communication problems are exacerbated by the extreme shortage of Latino health care professionals and other resources available. Institutional barriers often reflect the failure to consider what it means to provide good service as well as high-quality medical care. Reducing these barriers to medical care requires modifying governmental and institutional policies, expanding the supply of competent providers, restructuring delivery system incentives to ensure primary care and public health services, and enhancing service and satisfaction with care.

Health Care Reform↗