[Direct surgery of leprous neuritis].
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Biomedical subjects
Publications and source records attributed to P Giraudeau.
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I.--Treatment with BCG and DDS in lepromatous or borderline patients. II.--Value of BCG added to a prior and long-continued treatment with DDS or rifamipicine. III.--Value of various immunostimulants given previously to a treatment with BCG and chemotherapy. IV.--Value of lysate of Neisseria perflava as an immunostimulant associated with DDS in an initial treatment of lepromatous and borderline patients. V.--Results of a seventeen months treatment of lepromatous and borderline patients with a lysate of Neisseria perflava associated with DDS. The various therapeutic trials reported in these 5 papers demonstrate that hansenian nevritis conventionnally treated may show improvement when an immunostimulant (BCG or bacterial lysate or levamisole) is given either previously or in association with DDS or rifampicine or after such a treatment. It has still been observed that two immunostimulants given simultaneously have no good effect and that this association must be discarded.
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When medical treatment is not sufficient, surgery may still improve leprous neuritis by:--opening of osteo-fibrous tunnels where is an external compression fixing the level of physiological blockade: the elbow for the cubital nerve, the wrist for the median nerve, the peroneal neck for the peroneal nerve, the instep for the tibial nerve;--opening the thickened and consequently inextensible epineurium, inducing a release of the compression acting upon the nervous bundles and permitting their recovery if they are not yet destroyed. The film describes the various techniques immediately effective in hyperalgic neuritis and giving valuable recoveries in forms showing already a functional impairment.