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Biomedical subjects

P Gersbach

Publications and source records attributed to P Gersbach.

35 records · Page 2Linked to original sources

[Transitory subclavian steal induced by abnormal position of the arm and producing dangerous myocardial ischemia after mammary artery bypass].

Literature reports only eleven cases of subclavian steal syndrome after CABPG through a left internal mammary artery (LIMA). In 2 asymptomatic patients the diagnosis was established at routine control angiography. In all cases some degree of stenosis of the subclavian artery (SCA) proximally to the emergence of the LIMA was demonstrated and quickly corrected by means of a left carotido-subclavian bypass graft. We report the observation of a patient who presented already at the 11th postoperative day recurrent instable angina with typical ECG changes. This case is absolutely exceptional for two reasons: Postoperative angina appeared exclusively during sleep but never under exercise. Careful interrogation revealed that the patient always slept with his hands crossed under the neck, in a position comparable to the Adson test. In this critical position of the arms, typical attacks of angina and ECG changes could be easily and repetitively induced. A steal syndrome though the LIMA bypass could be demonstrated at coronary angiography and simultaneous measures of the systolic blood pressure on both arms revealed a difference over 20 Torrs which became apparent exclusively in upright position of the arms. All the symptoms disappeared spontaneously within a few months. Six months postoperatively the ECG was normal even in the upright position of the arms and no blood pressure difference could be evidenced anymore. A control coronary angiography showed a patent and well-functioning LIMA graft on the LAD and the absence of any retrograde perfusion of the LIMA graft. These different transitory symptoms have probably to be related to a postoperative compression of the proximal SCA by hematoma or by oedematous reactions.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

[Retransfusion of thoracic drainage blood: qualitative analysis].

In a prospective randomized study 10 patients received their shed mediastinal blood after elective coronary artery bypass surgery and were compared to 10 control patients without retransfusion. The quality assessment can be summarized as follows (mean +/- 1 SD): 1. Hemoglobin concentration of the shed blood was 9.6 +/- 1.45 g/dl. 2. The energy rich phosphate compounds of the shed blood erythrocytes were 2.6 +/- 0.8 mumol/gHb ATP (70% of the patients preoperative value) and 14.8 +/- 4.2 mumol/gHb 2.3-DPG (normal). 3. Proteins, immunoglobulins and especially albumin in the shed blood were not significantly different from the patients own values. 4. No electrolyte changes, safe for a slight increase in potassium (5.7 +/- 0.7 mmol/l). 5. The activated clotting time of the patient did not change during retransfusion. 7. Plasma free hemoglobin was elevated to 211.1 +/- 44.3 mg/dl in the shed blood; however, no significant increase could be noted in the retransfused patients and no hemoglobinuria occurred. Postoperative retransfusion of shed mediastinal blood is a simple and safe method of autologous transfusion early after cardiac surgery and should be combined with other methods of blood salvage. The qualitative advantages of blood retransfusion consist in the absence of storage damage and in the preservation of autologous proteins and immunoglobulins.

Blood Chemical Analysis↗

[Indications and limitations of the exertion ECG in the diagnosis of left ventricular aneurysms].

By retrospective analysis of 1415 bicycle ergometer exercise stress tests, 108 patients were selected for coronary angiography and left ventriculograms at least 3 months after acute anterior wall myocardial infarction. The ECG of 55/108 showed elevation of the ST-segment of 1 mm or more during exercise. 82% displayed an aneurysm defined by diastolic and/or systolic bulge (dyskinesis) of the anterior ventricular wall: sensitivity 82%, specificity 96%, positive predictive value 97%. The bicycle exercise stress test is a strong, noninvasive predictor of left ventricular aneurysm.

Adult↗

[Risk factors in coronary arteriosclerosis in women].

108 women aged 28 to 74 years underwent cardiac angiography for evaluation of chest pain or other heart disease. 29 were found to be free of coronary disease and formed a control group. Multi-variable analysis indicated that hypercholesterolemia, hypertension, familial coronary disease and diabetes were the most relevant atherogenic risk factors.

Adult↗

[Long-term evolution of children operated on for tetralogy of Fallot].

While open heart surgery has much improved the prognosis of tetralogy of Fallot, surgical repair does not usually restore completely normal anatomy. Residual defects include some degree of pulmonary stenosis, pulmonary regurgitation (unavoidable if the pulmonic valve and valve ring need to be widened by patch), and, sometimes, residual ventricular septal defect. In addition, left and right ventricular dysfunction of mild to moderate degree, unrelated to residual lesions, may be observed. Other late complications may arise from conduction disturbances and ventricular arrhythmias. The occurrence of late sudden death is related to such rhythm disturbances, it occurs particularly in patients with ventricular premature beats on routine ECGs and is probably due to ventricular fibrillation. Patients with such premature beats must therefore be treated with antiarrhythmic drugs. In spite of these late complications, the majority of patients lead a normal life and professional integration is usually excellent. Many patients practise sports. Exercise tests late after surgery show mild or moderate decrease in maximal exercise performance if there are residual lesions of significance, and especially when there is more than one such residua (e.g. pulmonic stenosis and regurgitation). Life expectancy should be normal, at least for postoperative patients with minimal residual lesions.

Age Factors↗

[Drainage in surgery of the heart and great vessels].

Based upon some recent experience with pericardial drainage a comparison is established between the surgical procedure and the needle-punction; the best approach to the pericardium, depending on the nature of the effusion is described. In the second part, the value of various types of drainage used since 19 years in the cardiac surgery is reviewed on the basis of our own experience with more than 7000 cases.

Adult↗

[Paralysis after tetanus prevention].

A rare case is presented of isolated paralysis of the left dentatus muscle in a 29-year-old woman following antitetanus vaccination by adsorbed toxoid injection in the left shoulder. In the light of a literature review the peculiarities of this case are pointed out and the risk factors which emerge from the patient's history are stressed. The discussion centres on the most favorable site for injection of toxoid, the controverted etiology of the affection and the desirability of some form of treatment.

Accidents, Traffic↗