[Influence of obscurity and occlusion of the eyelids on the control of ocular movements].
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Biomedical subjects
Publications and source records attributed to P Gerin.
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The authors studied the EGGs of 262 cases of post-traumatic coma and drew the following conclusions: 1. If the EEG shows sleep activity immediately after cranial trauma, the prognosis is generally good. 2. The existence of electrical reactivity to sensory stimulation is a favourable sign and examination of the symmetry of reactions often demonstrates a focal lesion which is not otherwise apparent. However, the absence of localizing signs in the EEG does not necessarily preclude the existence of an intracranial focal lesion; nor do signs of focalization necessarily confirm the existence of a lesion. 3. In equivocal cases, the echo-EG and arteriography should be contemplated. 4. Focal irritative abnormalities in an elderly patient suggest a very poor prognosis. 5. A recording which implies mtabolic disorder should prompt the immediate search for the causal disturbance. If correction of the metabolic disturbance is not followed by rapid improvement of the EEG, the prognosis is very unfavourable. 6. A focal lesion associated with the coma will affect the prognosis but surgical correction of the lesional effects may also get rid of the disturbances of consciousness.
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The authors present a contribution to the french validation of the self-rating questionnaire of the depression in the elderly proposed by Yesavage and Brink (1982), the Geriatric Depression Scale (30 items). This study focusses on the assessment of the homogeneity and of the unidimensionality of this scale. 99 aged women living in old-people homes or attending a geriatric somatic day-hospital, not known to be psychiatrically ill, filled the GDS and were interviewed by either a psychiatrist or by a clinical psychologist. This interview yielded 44 cases of Major Depressive Disorder or of Dysthymia (DSM III). Firstly, we have applied the classical correlational methods of assessment of scale Reliability and Construct Validity: Cronbach's coefficient alpha and item-total correlations (homogeneity) and Principal Component Analysis (PCA) without rotation. Then, we have performed a Rasch Model Analysis: this method which belongs to the general frame of Latent Trait Theory relies on a probabilistic model of subject's response to individual questions. In the Rasch model, the response probability of a given subject to a given item is a logistic function of the difference between the item location parameter and the subject location parameter along a single continuous latent dimension. Our results have shown that the Cronbach's alpha was very high (.902) and that the item-total correlations were quite satisfactory (mean .470), thus giving a strong impression of homogeneity (similar to unidimensionality for many authors).(ABSTRACT TRUNCATED AT 250 WORDS)
The aim of this work, which was performed in a Crisis Centre in Geneva, Switzerland, was to study the relationship between a patient's long-term follow-up and the range of the patient's difficulties as assessed during screening by a clinician. Out of the 78 patients who were referred to the Centre during a two-month period in 1985, 31 were followed-up during a complete crisis intervention program. All these patients with severe symptoms would have been hospitalized if they had not been transferred to this program. The clinician's opinion of these patients' difficulties was obtained by using a questionnaire containing open-response questions. The data obtained was then subjected to specific content analysis. The patients' clinical state, diagnosis and changes during therapy were also assessed, using various questionnaires. Our results show that there is a negative correlation between the number or range of difficulties attributed and noted by the clinician and the long-term evolution of the patient, especially after two years. This relationship is dependent on the number, not the type of difficulties noted. Thus, although it is not possible to generalize these results, we have shown that it is possible to study parameters involved in the process of a psychotherapeutic-type treatment, using a questionnaire. We have also shown that crisis intervention can be considered as an especially interesting analogue of the early steps of psychotherapy, spread over a longer period. This is an aspect which is rarely studied.
"Assessment" (of outcome and of factors of outcome) and "psychotherapy" are first defined. Although the aims of these surveys are deeply varying depending on their initiators (therapists or administrations), they share the same objects and the same methodological problems. This common problematic is specific, different from those prevailing for epidemiology or therapeutic trials; it also varies depending on the psychiatric and cultural background (for instance, depending on the side of the ocean). The choice of variables is discussed for objects (patients, families, therapists, institutions), sources (self and hetero-questionnaires) and exploratory levels (from symptoms to subjective quality of life). This leads to the choice of instruments, the interest of open ended questions and specific modalities of responses being emphasized. After a discussion of several methods of outcome assessment, the study of factors of change includes a comparison of the naturalistic and experimental approaches. Although these studies encounter some risks and limitations, they have an obvious clinical interest.
The questionnaire "Profile of the Subjective Quality of Life" (in french, PQVS) is devoted to the assessment of quality of life in therapeutic trials. On a sample of 588 subjects, factorial analysis confirm that it is not restricted to the assessment of the health, as most of the instruments actually available for that purpose. Its internal consistency is high. Correlations clearly show that its specific questions assessing the degrees of a) satisfaction and b) involvement (concerning each item) are clearly understood as having different meanings. Multiple regressions demonstrate that these specific questions strongly contribute to the explanation of the global quality of life or of the satisfaction concerning each item. Its reliability is good. It is very well accepted, and completed in no more than 15 to 30 minutes. This questionnaire is thus matching the criteria defining an effective assessment of the quality of life.
A study whose aim was to define the role of psychological factors in prematurity etiology has led us to develop a methodology for evaluation of personality which could have a connection with the occurrence of a premature birth. The proposed method--interviews based on free association followed by the construction of questionnaires serving as a base for an epidemiological study--seem to us applicable in order to show the psychological components which intervene in the occurrence of a somatic illness.
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The aims of this study were 1) to study the quality of life in diabetic patients receiving one of two different forms of insulin delivery and 2) to check in this disease, the reliability and responsiveness of a questionnaire (SQLP: subjective quality of life profile) which we have previously used and validated in other pathological states. A total of 743 Type 1 diabetic subjects, receiving two different forms of insulin injection completed this questionnaire twice, at a monthly interval. These patients stressed a certain number of somatic manifestations as well as their difficulty to move around or perform every-day life activities. The results from this trial show that the questionnaire was capable of demonstrating that the easiest mode of insulin injection was selectively and significantly related to a higher satisfaction with being able to move around.
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