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Biomedical subjects

P Georgi

Publications and source records attributed to P Georgi.

At least 73 records · Page 4Linked to original sources
PubMed1980

Posture-induced disturbance of pertechnetate flow and I-123 iodohippurate transport in some renal graft recipients with hypertension.

Iodohippurate renography and rapid serial scintigrams with pertechnetate were done in 27 allograft recipients in supine and standing positions. Posture-dependent iodohippurate transport and/or disturbance of pertechnetate flow pattern was found in nine of those examined. Patients demonstrating these abnormalities were found to be hypertensive. We suggest a causal relationship between posttransplant hypertension and the described posture-induced alterations of tracer transit.

Female↗
PubMed1980

[Pre and intraoperative volume determination of craniopharyngioma cysts (author's transl)].

Exact cystic volume measurement is a prerequisite to proper 90Y dosage in the therapy of of intracavitary monocystic craniopharyngiomas. The method of intraoperative volume measurement by a radionuclide dilution technique is compared to results obtained by preoperative volumetry using computer tomography. Both methods gave congruous results. It is pointed out that gamma camera scintigrams are essential for the early detection of complications.

Adolescent↗
PubMed1980

[Discriminant analysis in the quantitative evaluation of lung scintigrams (author's transl)].

Lung scintigrams made with 99mTc-MAA in a group of patients and a control group were compared and classified by a discriminant analysis based on two regional methods and several parameters for quantitative characterisation of the regions. Improved results are gained by a regional division of the lung orientated in the pulmonary lobes and segments and by combining several parameters.

Analysis of Variance↗
PubMed1979

Ventilation studies with krypton-81m.

Nuclear medicine offers well-established methods for regional lung function assessment in the preoperative evaluation of patients with lung disease. The perfusion study with Tc-99m macroaggregates is simple and can be performed without special precautions in radiation shielding. The ventilation study with Xe-133, however, requires more elaborate apparatus as well as special procedures to collect the exhaled radioactive rare gas. Nuclear medicine departments with access to short-lived radionuclides from a nearby cyclotron can use the krypton isotope Kr-81m. The physical half-life of Kr-81m is 13 s. Its gamma energy of 190 keV is optimal for gamma cameras. Kr-81m can be used as a medical isotope in spite of its short half-life. It can be eluted with a continuously flowing gas from the generator containing the mother nuclide Rb-81 which has half-life of 4.6 h. This short half-life not only simplifies radiation protection but allows repeated studies in different projections as well. Examples of comparative studies with Xe-133 and Kr-81m are presented. The importance of taking not only anterior and posterior pictures but also lateral oblique views is stressed.

Half-Life↗
PubMed1979

[The importance of scintimetry in the differential diagnosis of roentgenological areas of increased "translucence" in the skeleton of children (author's transl)].

A random selection of lesions representing osteolytic bone processes was evaluated with the "region-of-interest" technique in order to determine whether scintimetry can be helpful in the differential diagnosis of such processes in children. Bone tumours with structural densification, as well as osteomyelitides, were reviewed for comparative purposes. It was found that scintigraphy of the skeleton, while supplying additional and clinically quite interesting information, does not make any substantial contribution to the differential diagnostic clarification of roentgenological translucence in the skeleton of children.

Bone Resorption↗
PubMed1979

Renal graft evaluation with pertechnetate and I-131 Hippuran. A comparative clinical study.

This retrospective study compared standard clinical and biochemical data from 50 graft recipients against 533 I-131 Hippuran sequential scintigrams and 515 [99mTc]pertechnetate serial scintigrams. All grafts included in this study are cadaver kidneys. The majority of the studies were made during the early posttransplantation period. Anuria or oliguria of at least 4 days duration was seen in 18 patients. The study spans 574 days of oliguria during which 136 dual-tracer studies were made. I-131 Hippuran renography of functioning grafts was carried out 397 times, and the Tc-99m sequential scintigraphy 379 times. In all, 47 espisodes of actue rejection were registered clinically in functioning gfafrs, 36 of which were recognized during Hippuran renography and 38 with the pertechnetate study. False-positive errors were seen 12 times during renography. The study also demonstrated that furosemide will significantly and predictably influence renography and the pertechnetate study. This seems noteworthy since furosemide is extensively used in posttransplant management.

Adolescent↗
PubMed1979

[Clinical relevance of 111In-bleomycine in intrathoracal neoplasms (author's transl)].

With a medium storage ratio of 1:1.4 between sound and neoplastic lung tissue additional diagnostic information cannot be obtained by positive tumor scintigraphy with 111In-bleomycine. This may be accounted for on the one hand by the diffuse borders of the storage foci, on the other hand by the relatively high storage of radioactivity in normal lung tissue.

Aged↗
PubMed1978

[Disturbances in C.S.F. circulation after subarachnoid bleeds--a comparison of pneumoencephalographic and scintigraphic findings (author's transl)].

Haemorrhages into the subarachnoid space lead to scarlike changes in the leptomeninges in some patients. If these changes reach a certain severity, circulation of the C.S.F.. is compromised and absorption reduced. This eventually results in ventricular dilatation which, in severe cases, is clinically manifested by dementia, motor ataxia and incontinence. The early stages of the disturbance in C.S.F. circulation were examined scintigraphically in 165 patients with spontaneous traumatic or operative subarachnoid bleeding. In the presence of abnormal findings which suggested the need for C.S.F. shunting, air encephalography was carried out in addition. Special attention was paid to the demonstration of the extent and localisation of occlusions of the basal cisterns and of the cortical subarachnoid spaces. Typical scintigraphic and pneumoencephalographic findings are demonstrated and their diagnostic value compared.

Humans↗
PubMed1978

Evidence of possible association of nephrolithiasis and nephroptosis.

Two separate populations, one consisting of 100 patients with renal stones and one consisting of 81 patients with nephroptosis were examined to determine whether an association may exist between excessive renal mobility and renal stone formation. The statistical analysis of the data suggests a direct relationship between nephroptosis and the occurrence of renal stones.

Adolescent↗
PubMed1977

[Comparison of endoscopic biopsy and scintiscans in liver diseases (author's transl)].

The diagnostic possibilities of liver scintiscans with indium-113m acetylacetonate were investigated in 314 patients. The results obtained were compared with our own endoscopic biopsy investigations. The scintiscans give information on the stage of the disease, but in contradistinction to the laparoscopic biopsies, not on etiology or activity of the disease. In contrast to the endoscopic biopsies, scintigraphy carries no risk. The advantage of the indium-113m acetylacetonate we used lies in the low radiation exposure.

Biopsy↗
PubMed1977

Position dependent renogram changes of the mobile kidney.

The present study evaluates the isotope renograms, obtained in prone and upright position of 87 patients with 93 mobile kidneys. Scintiphotos were made to determine the extent of renal movement. The transient position abnormality of the kidney was compared to the position dependent isotope renogram changes. It was possible to describe three types of floating kidney each with a characteristic motion and position dependent function disturbance. One form of renal ptosis, ptosis with ventral rotation, was commonly associated with a 2nd phase renogram abnormality and with hypertension.

Adult↗