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Biomedical subjects

P Gautam

Publications and source records attributed to P Gautam.

10 recordsLinked to original sources

Accumulation of Acid Orange 7, Acid Red 18 and Reactive Black 5 by growing Schizophyllum commune.

The effect of Acid Orange 7, Acid Red 18 and Reactive Black 5 on the growth and decolorization properties of Schizophyllum commune was studied with respect to the initial pH varying from 1 to 6 and initial dye concentration (10-100 mg/L). The optimum pH value was found to be 2 for both growth and color removal of these azo dyes. Increasing the concentration of azo dyes inhibited the growth of S. commune. It was observed that S. commune was capable of removing Acid Orange 7, Acid Red 18 and Reactive Black 5 with a maximum specific uptake capacity of 44.23, 127.53 and 180.17 (mg/g) respectively for an initial concentration of 100 mg/L of the dye. Higher decolorization was observed at lower concentrations for all the dyes. Finally it was found that the percentage decolorization was more in the case of Reactive Black 5 dye compared to the other two dyes used in the present investigation.

Analysis of Variance↗

Rh iso-immunisation with syndrome of hepatocellular damage. An unusual presentation with review of literature.

Rh iso-immunisation is prevalent in many underdeveloped countries. Severe haemolytic anaemia with or without hydrops fetalis, dangerous level of haemolytic unconjugated bilirubin and imminent bilirubin encephalopathy are the hallmarks of haemolytic disease of the newborn. The investigative protocols and efficient management of this entity are adequately described in literature. An unusual manifestation of this disease with severe hepatocellular damage and conjugated hyperbilirubinemia was noticed in a neonate. The literature has been reviewed and the specific symptom complex has been attributed to 'syndrome of hepatocellular damage', which is a rare accompaniment of haemolytic disease of the newborn. Attempts have been made to describe the syndrome in detail, with latest reference regarding complete workup and management. Few useful tips for prevention of the disease in a community background have been suggested.

Adult↗

Complex camptopolydactyly: an unusual hand malformation.

Different types of polydactylies and other hand malformations are commonly seen. Here, we describe a very unusual type of hand malformation characterised by campto-polydactyly with totally disorganised configuration of digits. The role of possible genes involved in development of hands and digits is discussed.

Bone Morphogenetic Proteins↗

Unplanned readmissions of elderly patients.

OBJECTIVE: This study was undertaken to determine the prevalence of unplanned readmissions in Geriatric Medicine in Aberdeen and to examine their nature in order to establish how many of them were avoidable. DESIGN: Patients living within Aberdeen who were discharged from Care of the Elderly Assessment Wards in one hospital between 1 August 1994 and 31 January 1995 were identified. Any subsequent unplanned readmissions of this population to any local hospital within 28 days were identified and formed the study's sample. Subsequent comparison with the non-readmitted population yielded readmission rates. The nature of each episode was investigated by obtaining a wide range of data (e.g. from medical and nursing notes) soon after readmission and by the audit team subsequently identifying principal and associated causative factors. A questionnaire was also sent to the discharging consultant and the patient's GP seeking opinions on whether readmission was avoidable and these were weighted equally with the audit team's opinion in order to establish avoidability. SETTING: The patients were all discharged from the nine Care of the Elderly Assessment wards at Woodend Hospital in Aberdeen and readmitted to any NHS hospital within Aberdeen. SUBJECTS: The subjects were patients living within Aberdeen who satisfied the above criteria. RESULTS: There were 109 episodes of readmission resulting from 713 discharges, making a readmission rate of 15.3%. The readmitted population was elderly with multiple medical problems; 50% lived alone. In 87% of cases the principal causative factor in readmission was medical, most commonly involving relapse of illness. The remaining 13% were 'social' in nature. Response rates to the questionnaire by GP's and Consultants were excellent (96% and 99% respectively) and 34 cases emerged where either party, or both, thought readmission to be avoidable. These cases were subject to further review by the audit team and in this way 16 of the 34 cases were judged to be avoidable. The main area for improvement was considered to be pre-discharge assessment of home circumstances. CONCLUSION: The majority of unplanned readmissions were medical in nature and unavoidable. The use of rates of unplanned readmission as a measure of clinical outcome in care of the elderly is unsatisfactory as they do not accurately reflect the quality of in-patient care.

Aged↗

Hypothermia in the elderly: sociomedical characteristics and outcome of 86 patients.

A comprehensive retrospective study analysing the case records of 86 hypothermic elderly patients who were treated according to a standard protocol in our department between 1980 and 1985 is presented. Hypothermia was found to occur not only in the frail, demented and disabled elderly men and women, but also in apparently healthy elderly individuals living with their families and in rest homes (40%). The level of consciousness was not related to the degree of hypothermia but to the underlying pathology. There was no correlation between the severity of hypothermia and mortality. Fatality was less among the group receiving substantial services, but the overall mortality within 48 hours was 36%. Early detection improved survival. Eleven per cent had recurrence of hypothermia and 90% of those who survived hypothermia died within one year. Prolonged duration of hypothermia, high levels of neutrophilia, blood urea and amylase, cardiac arrhythmias and impairment of consciousness were found to be associated with high mortality.

Aged↗