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Biomedical subjects

P G Rosario

Publications and source records attributed to P G Rosario.

16 recordsLinked to original sources

Kaposi's sarcoma of the parotid gland in acquired immunodeficiency syndrome.

Parotid gland enlargement is common in patients infected with the human immunodeficiency virus. Although parotitis is the usual histopathological feature in such cases, patients with acquired immunodeficiency syndrome are at high risk of developing both lymphoma and Kaposi's sarcoma of the parotid gland. Human immunodeficiency virus, however, is not detected within the parotid parenchyma even in the presence of Kaposi's sarcoma. The pathway of the virus' entry into the saliva remains unknown.

Acquired Immunodeficiency Syndrome↗

Coronary artery endarterectomy for retrieval of entrapped percutaneous angioplasty catheter.

A 70-year-old patient underwent percutaneous transluminal coronary angioplasty of a calcified tight mid-right coronary artery lesion, when the balloon burst and could not be retrieved. Even on cardiopulmonary bypass, the catheter could not be extracted through a proximal aortotomy. The patient had a distal reversed saphenous vein graft inserted into the right coronary artery. The catheter was ultimately removed after an endarterectomy of the calcified lesion.

Aged↗

Chest wall hamartoma in an adult: an unusual chest wall tumor.

An asymptomatic intrathoracic mass was demonstrated on imaging studies in an adult. Operative removal was accomplished and it proved to be an extrapulmonary hamartoma arising from the soft tissue of the chest wall. This represents a rare location of this benign tumor in an adult.

Adult↗

Chemical pleurodesis for spontaneous pneumothorax in a patient with AIDS.

Persistent air leak and failure of the lung to expand completely after closed thoracostomy complicate the course of spontaneous pneumothorax in patients with AIDS. In such cases, attempts to discontinue chest tube drainage may fail. The following is a case of a patient with AIDS and spontaneous pneumothorax who responded to chemical pleurodesis with tetracycline.

AIDS-Related Opportunistic Infections↗

Spontaneous rupture of human renal allografts.

Preservation of renal allografts following spontaneous rupture is a surgical challenge. Salvage was attempted in 3 patients. Despite successful repair in all 3, transplant nephrectomy was ultimately required in 2 patients because of irreversible rejection. The third patient is doing well forty-eight weeks after transplantation.

Adult↗

Risks of human immunodeficiency virus infection to patients and healthcare personnel.

The risk of nosocomial human immunodeficiency virus (HIV) infection among hospitalized patients comes almost exclusively from transfusion of fresh blood products. Current estimates of the risk of HIV infection from the transfusion of blood or components vary from 1/40,000 to 1/250,000 (0.0025% to 0.0004%), with the most probable likelihood estimated to be 1/153,000 (0.0007%). The major route of transmitting such HIV infection is via blood collected during the interval between infection of the donor and development of a detectable circulating antibody level to the AIDS virus (i.e., the "window period"). The current risk to hemophiliacs receiving treated coagulation factor concentrates is negligible. The risk to healthcare personnel of acquiring HIV infection from accidental puncture wounds and from handling HIV-infected blood or body fluids is 0.42% per episode. Most reported seroconversions have resulted from penetrating injuries with sharp objects contaminated with HIV-positive blood. The degree of risk to healthcare workers will vary with the community, the patient population served, and the frequency of penetrating injuries.

Body Fluids↗