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Biomedical subjects

P G Litvinov

Publications and source records attributed to P G Litvinov.

18 recordsLinked to original sources
PubMed1992

[The use of protease inhibitors in the treatment of burn wounds].

The results of experimental and clinical studies of the effect of contrykal and aminocaproic acid on tissue regeneration in deep burns are presented. In the experiment, by means of planimetric, histologic, histochemical and biochemical methods of investigation, the positive effect of inhibitors on healing of the burn wounds is shown. In treatment of 272 patients with deep burns, it was established that use of protease inhibitors at the phase of regeneration contributed to 2-fold acceleration of marginal epithelization, shortening of time of would preparation to autodermoplasty by 3-4 days, increase in effectiveness of survival of the cutaneous flaps. A possibility of wide clinical use of proteolysis inhibitors predominantly in combination with antibiotics is shown.

Animals↗
PubMed1986

[Use of epsilon-aminocaproic acid for treating granulating burn wounds].

Results of the application of synthetic inhibitor of proteolytic enzymes epsilon-aminocaproic acid in the treatment of granulating burn wounds are described. High effectiveness of the aminocaproic acid in healing of granulating wounds after burns is shown as well as in preparing great granulating burn wounds for autodermoplasty and the take of transplanted autodermic flaps.

Adolescent↗
PubMed1986

[Use of liquid crystals for determining burn depth].

The article describes results of the application of liquid-crystal thermoindicating films for obtaining an objective assessment of the burn depth in 30 patients. The proposed method is recommended as an additional objective test of the true burn depth. The method is harmless for the patient, simple, does not require expensive apparatus and may be used both at the hospital and at the prehospital stage.

Adolescent↗
PubMed1978

[Effect of elastase inhibitor on proteolytic enzyme activity in experimental wounds].

The protease activity of the wound walls and in the wound washings during the experimental skin and muscular wounds treatment with a Trieline-containing ointment, which is an inhibitor of the elastinase, and with some other proteolytic enzymes has been determined on white rats. It is suggested, that the application of such inhibitors suppresses the catabolism rocesses and stimulates the regenerative ones.

Animals↗