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Biomedical subjects

P Frasson

Publications and source records attributed to P Frasson.

At least 19 recordsLinked to original sources

[Laparoscopic cholecystectomy. A clinical case series].

Laparoscopic cholecystectomy is a minimally invasive and highly effective technique for gallstone disease. The authors report their experience of laparoscopic cholecystectomy. Between September 1992 and December 1994 we performed laparoscopic operations on 212 patients with gallstone disease. Our series included 149 female and 63 male patients; 29 patients was converted intraoperatively to the open procedure. Laparoscopic cholecystectomy is the best surgical approach for the treatment of cholelithiasis: it reduces postoperative pain and hospital stay, has cosmetical and financial benefits.

Adult↗

[Duodenal adenocarcinoma].

The authors report 4 cases of primitive malignant duodenal tumors. Adenocarcinoma of the duodenum is a rare tumor and its clinical symptoms are various and not specific. The most common picture is the occlusive stenotical one, where complications are numerous and frequent. The radiographical pictures are represented either by a short neoplastic stenosis or by lacunose aspects or by strictures of the lumen between two normal segments. Endoscopy allows biopsy and therefore helps to secure histological diagnosis. The prognosis of duodenal cancer is severe as diagnosis is late. The possible therapy is surgical and consists either in palliative interventions (digestive and biliary derivations) or in the radical ones (duodenocephalus-pancreasectomy or segmentary duodenectomy). In order to improve patients survival, which is rare and till 5 years maximum, early diagnosis is necessary.

Adenocarcinoma↗

[Deep vein thrombosis in surgery].

Deep vein thrombosis is still an underestimated and often unrecognised diseases both in Italy and abroad despite being far from rare and in spite of its severe complications and often disabilitating sequelae. It is a disease which is becoming more frequent due to increased life expectation, the larger number of operations on elderly patients, and the increased frequency of limb injuries. General and specialised surgery is often hampered by this complication. This has raised interest in a more detailed knowledge of the mechanisms leading to DVT, and the correct employment of the latest equipment which enable diagnosis to be made and daily monitoring of the disease during its evolution. But the greatest efforts must be reserved for preventive measures in order to achieve a statistically significant reduction in the incidence of the disease in operated patients. It is to be hoped that a greater awareness of thromboembolic diseases will allow this to be achieved in the future.

Humans↗

[Non-epithelial benign gastric neoplasms].

The Authors report five cases of benign neoplasm of the stomach: 2 leiomyoblastomas, 2 leiomyomas and 1 ganglioneuroblastoma, underlining its rarity. After a review of the literature, the anatomo-pathological, clinical and therapeutical findings are described. The difficulty of early diagnosis is underline and the need for surgical therapy states.

Aged↗

[Splenic pregnancy. Apropos of a case].

Still nowadays the extrauterine pregnancy causes the 10% of maternal deaths, also in the most developed countries. The splenic localization is really exceptional. The authors of this article describe a case they have studied, by drawing the attention on the criteria followed in order to obtain an early and correct diagnosis for a reduced mortality rate.

Adult↗

[Radiation-induced intestinal injuries].

Postoperative radiation after the removal of radiosensitive tumours may cause acute or chronic intestinal lesions. In some cases severe complications requiring one or more operations may arise even years later and unfortunately the morbidity and mortality rates are high. The paper presents a discussion of the clinical onset of these pictures as well as diagnostic and therapeutic possibilities in the light of personal experience and information obtained from the literature.

Humans↗

[Ultrasonic diagnosis of the central hyperechogenic area in lymph nodes. A sign of benign lymphadenopathy].

When identifying superficial lymphadenopathies by means of echotomography, the only accepted criterium of evaluation is still dimension. Only lymph nodes with a diameter longer than 0.5 cm are considered as potentially pathological, irrespective of their morphological characteristics. In the past two years an echotomographic study of the surface regions was carried out on 300 patients. Some suffered from unspecific solitary lymphadenopathies; most of the others were affected by stationary neoplasias, mainly situated in the cervical region. In many cases it has been possible to correlate the echotomographic and the histological results. Sixty-nine out of the 300 examined patients had lymph nodes with a central hyperechogenic area. Histology showed these lymph nodes to be the site of reactive hyperplasia. This characteristic has never been found in neoplastic lymph nodes. It has been hypothesized that this spot corresponds to the hilus of the lymph node and that, through its identification, it may be possible to distinguish benign from neoplastic lymph nodes.

Adolescent↗

[Preoperative ultrasonic diagnosis of metastasis to the cervical lymph nodes from otorhinolaryngeal neoplasms].

The results of a study on 30 patients with ear, nose and throat cancers are discussed; a comparison of clinical, ultrasound and histological findings for the preoperatory evaluation of the cervical lymph nodes has been carried out. Ultrasound technique is an excellent method of investigation for the staging "N" of such neoplasms; its contribution is very important for the following therapeutic program.

Diagnosis, Differential↗

[Study of the antispastic activity of prifinium bromide in motor dysfunction of the esophagus].

Motor disturbances of the oesophagus are attributable to hypermotility or hypomotility, or to peristaltic uncoordination of the upper or lower sphincter, or of the corpus. Endoesophageal manometry has enabled considerable progress to be made in the study of oesophageal dysfunction by allowing the spasm to be quantified. Treatment is poorly effective and its results are uncertain, save in the very few cases where surgery leads to resolution. For this reason, the efficacy of a new drug with marked antispastic properties, prifinium bromide, was investigated in 12 cases of megaoesophagus, of hiatal hernia, 6 of diverticulum, and 4 of dyskinesia in the light of the manometric values observed before and after its administration. The drug relieved spasm of the sphincters and corpus.

Deglutition Disorders↗

[Retroperitoneal liposarcoma].

The various aspects of this comparatively rare neoplasia are discussed on the basis of two cases of retroperitoneal liposarcoma and an analysis of the literature. Consideration are expressed on the clinical symptoms, the pathological anatomy, its marked tendency to evolve with repeated local relapses and the need to properly localise the mass and the feeding peduncles prior to the operation, so that radical exercise can be performed, since this leads to a more favourable long-term prognosis. The utility of radiotherapy, which leads to a lengthened period of freedom from the disease and to an increased survival time, is also stressed.

Adult↗

[Usefulness of the early study of intrathoracic digestive anastomoses].

The appearance of a dehiscence after an operation of oesophageal resection and reconstruction with stomach, jejunum or colon, constitutes a highly serious event frequently leading to the patient's death. Early recognition of dehiscence is therefore important for the purpose of starting adequate therapy as quickly as possible and preventing the rise and establishment of those lesions which condition an irreversible trend of the clinical condition. In this note the means today available for early diagnosis fo fistula, with particular reference to early radiological examination, are discussed. Early diagnosis and adequate prompt treatment may, in our opinion, lead to an improvement in the poor results reported by a number of surgical schools.

Colon↗

[Upward extension of esophago-gastric resection in carcinoma of the cardia: our current trend in the light of experience in 52 cases].

A first lot of patients (18 cases) operated for carcinoma of the cardias, with oesophageal resection performed at a distance of 4-5 cm. from the neoplasia, evidenced high mortality (7 cases) within the first twelve months. In a second lot of patients (17 cases), a study of the oesophageal section was made and showed invasion in 7 cases; this led to the level of the oesophageal resection being extended to a distance of 8-10 cm. from the tumour; in 17 cases thus operated (third lot) only one case of invaded oesophageal section was found. Systematic extension of the oeophageal resection, in cases of cancers of the cardias, to the level of the inferior pulmonary vein is therefore proposed in order to obtain a radical surgical result.

Adenocarcinoma↗